The integration of Spanish and Portuguese organ music within the liturgy from the latter half of the sixteenth to the eighteenth century by Nelson, B

“…</p> <p>The prescriptions to the organist given in the ecclesiastical constitutions and how these may have been realized in the Canonical Hours and in the Mass constitutes the essence of part two of this thesis. …”

PINK1-mediated mitophagy contributes to glucocorticoid-induced cathepsin K production in osteocytes by Jun Yuan, You-shui Gao, De-lin Liu, Andrew Chi Pang Tai, Hong Zhou, John M. Papadimitriou, Chang-qing Zhang, Ming-hao Zheng, Jun-jie Gao

“…Interestingly, GC’s activation effect towards cathepsin K via mitophagy was found to be independent on the canonical autophagy as this effect was not impeded when inhibiting the canonical autophagy via Atg5 suppression. …”
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Structure and dynamics of phytoplankton in an Amazon lake, Brazil by Ise de Goreth Silva, Ariadne do Nascimento Moura, Enio Wocyli Dantas, Maria do Carmo Bittencourt-Oliveira

“…We collected water (temperature, pH, Secchi depth and conductivity) and phytoplankton samples from the subsurface, middle of the water column, and approximately 30cm above the bottom, over 24-hour sampling periods, from a central station in the lake. …”
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Stimulus-Selective Response Plasticity in Primary Visual Cortex: Progress and Puzzles by Montgomery, Daniel P, Hayden, Dustin J., Chaloner, Francesca A., Cooke, Samuel F., Bear, Mark F

“…Second, SRP does not manifest within a recording session but only emerges after an off-line period of several hours that includes sleep. Third, SRP requires not only canonical molecular mechanisms of Hebbian synaptic plasticity within V1, but also the opposing engagement of two key subclasses of cortical inhibitory neuron: the parvalbumin- and somatostatin-expressing GABAergic interneurons. …”
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An Investigation of TorsinA Interaction Partners by Hernandez, Victoria J.

“…This finding deviates from Calnexin’s interactions with its canonical substrates, as Calnexin’s lectin domain specifically recognizes mono-glucosylated N-glycans. …”
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Similar Clinical Course and Significance of Circulating Innate and Adaptive Immune Cell Counts in STEMI and COVID-19 by Elena de Dios, Cesar Rios-Navarro, Nerea Perez-Sole, Jose Gavara, Victor Marcos-Garces, Enrique Rodríguez, Arturo Carratalá, Maria J. Forner, Jorge Navarro, Maria L. Blasco, Elvira Bondia, Jaime Signes-Costa, Jose M. Vila, Maria J. Forteza, Francisco J. Chorro, Vicente Bodi

“…The dynamics detected in STEMI (within a few hours) were replicated in COVID-19 (within a few days). …”
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Validation of an LC-MS/MS Method to Quantify the New TRPC6 Inhibitor SH045 (Larixyl <i>N</i>-methylcarbamate) and Its Application in an Exploratory Pharmacokinetic Study in Mice by Xiao-Ning Chai, Friedrich-Alexander Ludwig, Anne Müglitz, Michael Schaefer, Hai-Yan Yin, Peter Brust, Ralf Regenthal, Ute Krügel

“…TRPC6 (transient receptor potential cation channels; canonical subfamily C, member 6) is widespread localized in mammalian tissues like kidney and lung and associated with progressive proteinuria and pathophysiological pulmonary alterations, e.g., reperfusion edema or lung fibrosis. …”
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Stimulus-Selective Response Plasticity in Primary Visual Cortex: Progress and Puzzles by Daniel P. Montgomery, Dustin J. Hayden, Francesca A. Chaloner, Francesca A. Chaloner, Samuel F. Cooke, Samuel F. Cooke, Mark F. Bear

“…Second, SRP does not manifest within a recording session but only emerges after an off-line period of several hours that includes sleep. Third, SRP requires not only canonical molecular mechanisms of Hebbian synaptic plasticity within V1, but also the opposing engagement of two key subclasses of cortical inhibitory neuron: the parvalbumin- and somatostatin-expressing GABAergic interneurons. …”
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Investigation of the effects of B16F10 derived exosomes in induction of immunosuppressive phenotype in the hematopoietic stem cells by M. Atashzar, A. Ghanbari Asad, M. Mokhtari Tabar, S. Niknia, Z. Shokrolahi, N. Jooyan, M. Ataollahi

“…HSCs were cultured with or without B16F10 exosomes for 24 hours. Flow cytometry analyzed the expression of canonical MDSC surface markers CD11b, Ly6G, and Ly6C. …”
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Structure of the N-terminal domain of the circadian clock-associated histidine kinase SasA. by Vakonakis, I, Klewer, D, Williams, S, Golden, S, LiWang, A

“…Circadian oscillators are endogenous biological systems that generate the approximately 24 hour temporal pattern of biological processes and confer a reproductive fitness advantage to their hosts. …”

The urine albumin-to-creatinine ratio is a reliable indicator for evaluating complications of chronic kidney disease and progression in IgA nephropathy in China by Lu Huan, Luo Yuezhong, Wang Chao, Tu HaiTao

“…Higher tubular atrophy and interstitial fibrosis scores were also associated with a greater albumin-to-creatinine ratio, as observed in the canonical correlation analysis. Finally, the albumin-to-creatinine ratio and 24-hour proteinuria were associated with renal outcomes in univariate analyses. …”
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T cell dysfunction in elderly ARDS patients based on miRNA and mRNA integration analysis by Yumi Mitsuyama, Hisatake Matsumoto, Yuki Togami, Sayaka Oda, Shinya Onishi, Jumpei Yoshimura, Arisa Murtatsu, Hiroshi Ito, Hiroshi Ogura, Daisuke Okuzaki, Jun Oda

“…For both mRNA and miRNA-targeted mRNA, canonical pathway analysis showed that programmed death-1 (PD-1) and programmed cell death ligand 1 (PD-L1) cancer immunotherapy pathway was most activated and the Th2 pathway was most suppressed. …”
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Novel Indolyl-Benzimidazole Compounds Promote in vitro Wound Healing and Osteogenic Differentiation of Pluripotent Cells by Sheyda Najafi, Leonard Barasa, Jilian Maxine J. Frianela, Jawaher H. Alkhamisy, Sabesan Yoganathan, Jeanette C. Perron

“…Results: Sustained activation of non-canonical BMP signaling pathways was observed after 24-hour exposure to SY-LB-35 and SY-LB-57. …”
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Uncovering the neuroprotective effect of vitamin B12 in pneumococcal meningitis: insights into its pleiotropic mode of action at the transcriptional level by Larissa Marcely Gomes Cassiano, Larissa Marcely Gomes Cassiano, Marina da Silva Oliveira, Karina Barbosa de Queiroz, Alice Muglia Thomaz da Silva Amancio, Anna Christina de Matos Salim, Gabriel da Rocha Fernandes, Cláudia Martins Carneiro, Roney Santos Coimbra

“…The other hemisphere was used for RNA-Seq and RT-qPCR analysis.ResultsIn this study, adjuvant therapy with B12 was found to modulate the hippocampal transcriptional signature induced by PM in infant rats, mitigating the effects of the disease in canonical pathways related to the recognition of pathogens by immune cells, signaling via NF-kB, production of pro-inflammatory cytokines, migration of peripheral leukocytes into the central nervous system, and production of reactive species. …”
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Comparative microRNA profiling of Trypanosoma cruzi infected human cells by Natalia Rego, Natalia Rego, María Gabriela Libisch, Carlos Rovira, Juan Pablo Tosar, Juan Pablo Tosar, Carlos Robello, Carlos Robello

“…However, to our knowledge, there are no comparative studies on the microRNA changes that occur in different cell types in response to T. cruzi infection.Methods and resultsHere we investigated microRNA changes in epithelial cells, cardiomyocytes and macrophages infected with T. cruzi for 24 hours, using small RNA sequencing followed by careful bioinformatics analysis. …”
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BONCAT-FACS-Seq reveals the active fraction of a biocrust community undergoing a wet-up event by Ryan V. Trexler, Marc W. Van Goethem, Marc W. Van Goethem, Danielle Goudeau, Nandita Nath, Rex R. Malmstrom, Trent R. Northen, Trent R. Northen, Estelle Couradeau, Estelle Couradeau

“…One promising method to accomplish this is coupling bioorthogonal non-canonical amino acid tagging (BONCAT) with fluorescence activated cell sorting (FACS) which sorts cells based on whether or not they are producing new proteins. …”
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A domain decomposition technique for generation and scattering of acoustic waves by Lim, Wei Xian

“…For 2D viscous flow, a thermal plume under convective flow condition was simulated as a canonical study of thermoacoustic problem. Results demonstrate the feasibility of DDT in capturing not only the frequency of vortex shedding, but also the heat release rate fluctuation, while reducing approximately 13% of computational hours as compared to fully nonlinear simulations. …”
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The antimicrobial peptide gramicidin S alters proliferation and inhibits adhesion of L929 cell line fibroblasts by N. M. Alabedalkarim, V. P. Berest, N. M. Moiseieva, G. A. Bozhok, T. P. Bondarenko

“…Inhibition of the adhesive properties of connective tissue cells by gramicidin S is a new non-canonical effect of a known antimicrobial drug, which may indicate the possibility of using gramicidin S as an anti-neoplasm agent.…”
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Involvement of extracellular vesicles in the progression, diagnosis, treatment, and prevention of whole-body ionizing radiation-induced immune dysfunction by Roland F. Seim, Laura E. Herring, Angie L. Mordant, Micah L. Willis, Micah L. Willis, Shannon M. Wallet, Leon G. Coleman, Leon G. Coleman, Robert Maile

“…When given prophylactically (24 and 3 hours before exposure), MSC-EVs prolonged survival to the 9 Gy lethal exposure. …”
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Organometallic Palladium Reagents for Polypeptide Bioconjugation and Macrocyclization by Mallek, Aaron J.

“…High throughput techniques such as mRNA and phage display have been instrumental for discovering new peptidic protein ligands, however these techniques are limited with respect to incorporation of non-canonical amino acids. Synthetic libraries used in solution phase affinity selection-mass spectrometry (AS-MS) enable the use of nearly limitless non-canonical residues, however this approach is not compatible with macrocyclic peptides. …”
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