Questionnaire survey on point‐of‐care ultrasound utilization during cardiac arrest among emergency physicians in Hong Kong nork Lo, KT, Kwok, CH, Suen, KKW

“...Introduction: Although point‐of‐care ultrasound (POCUS) is recognized as a useful diagnostic and prognostic tool during the management of out‐of‐hospital cardiac arrest (OHCA), opposing viewpoints exist. The objectives of this study are to investigate the knowledge, attitude, and practice (KAP) in POCUS utilization during OHCA among emergency medicine (EM) physicians in Hong Kong and to identify their barriers. ...”

Prehospital randomised assessment of a mechanical compression device in cardiac arrest (PaRAMeDIC) trial protocol. nork Perkins, G, Woollard, M, Cooke, M, Deakin, C, Horton, J, Lall, R, Lamb, S, McCabe, C, Quinn, T, Slowther, A, Gates, S

“...BACKGROUND: Survival after out-of-hospital cardiac arrest is closely linked to the quality of CPR, but in real life, resuscitation during prehospital care and ambulance transport is often suboptimal. ...”

Pre-hospital assessment of the role of adrenaline: Measuring the effectiveness of drug administration in cardiac arrest (PARAMEDIC-2): Trial protocol nork Perkins, G, Quinn, T, Deakin, C, Nolan, J, Lall, R, Slowther, A, Cooke, M, Lamb, S, Petrou, S, Achana, F, Finn, J, Jacobs, I, Carson, A, Smyth, M, Han, K, Byers, S, Rees, N, Whitfield, R, Moore, F, Fothergill, R, Stallard, N, Long, J, Hennings, S, Horton, J, Kaye, C, Gates, S

“...Despite its use since the 1960s, the safety or effectiveness of adrenaline as a treatment for cardiac arrest has never been comprehensively evaluated in a clinical trial. ...”

Memory impairment in out-of-hospital cardiac arrest survivors is associated with global reduction in brain volume, not focal hippocampal injury. nork Grubb, N, Fox, K, Smith, K, Best, J, Blane, A, Ebmeier, K, Glabus, M, O'Carroll, R

“...BACKGROUND AND PURPOSE: More than 30% of out-of-hospital cardiac arrest (OHCA) survivors suffer significant memory impairment. ...”

A study on knowledge and practice on post cardiac arrest care among healthcare providers working in Emergency Department in Kelantan nork Ismail, Norhayati

“...To determine the level of practice of post cardiac arrest care among healthcare personnel in Emergency Department in Kelantan 3. ...”
Testu osoa

A prospective study on the outcomes of in-hospital cardiac arrest cases receiving cardiopulmonary resuscitation in two tertiary hospitals in malaysia nork Kwanhathai Darin, Wong

“...This study aims to tackle this by investigating the rates of survival outcomes for in-hospital cardiac arrest (IJ-IA) in our population. This study also serves as a starting point to hopefully create a database that other centers in the nation will be able to add on to. ...”
Testu osoa

Comparing outcomes of out-of-hospital cardiac arrest patients with initial shockable rhythm in Singapore and Osaka using population-based databases nork Okada, Yohei, Nur Shahidahn, Ng, Yih Yng, Chia, Michael Y. C., Gan, Han Nee, Leong, Benjamin S. H., Mao, Desmond R., Ng, Wei Ming, Edwin, Nausheen, Kiguchi, Takeyuki, Nishioka, Norihiro, Kitamura, Tetsuhisa, Iwami, Taku, Ong, Marcus Eng Hock

“...Previous research indicated outcomes among refractory out-of-hospital cardiac arrest (OHCA) patients with initial shockable rhythm were different in Singapore and Osaka, Japan, possibly due to the differences in access to extracorporeal cardiopulmonary resuscitation. ...”
Testu osoa

Biomarkers of brain injury after cardiac arrest; a statistical analysis plan from the TTM2 trial biobank investigators nork Moseby-Knappe, M, Levin, H, Blennow, K, Ullén, S, Zetterberg, H, Lilja, G, Dankiewicz, J, Jakobsen, JC, Lagebrant, A, Friberg, H, Nichol, A, Ainschough, K, Eastwood, GM, Wise, MP, Thomas, M, Keeble, T, Cariou, A, Leithner, C, Rylander, C, Düring, J, Bělohlávek, J, Grejs, A, Borgquist, O, Undén, J, Simon, M, Rolny, V, Piehler, A, Cronberg, T, Nielsen, N

“...<strong>Background<br></strong> Several biochemical markers in blood correlate with the magnitude of brain injury and may be used to predict neurological outcome after cardiac arrest. We present a protocol for the evaluation of prognostic accuracy of brain injury markers after cardiac arrest. ...”

Mechanical versus manual chest compression for out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised controlled trial. nork Perkins, G, Lall, R, Quinn, T, Deakin, C, Cooke, M, Horton, J, Lamb, S, Slowther, A, Woollard, M, Carson, A, Smyth, M, Whitfield, R, Williams, A, Pocock, H, Black, J, Wright, J, Han, K, Gates, S

“...The primary outcome was survival at 30 days following cardiac arrest and was analysed by intention to treat. ...”

Ventilation management and outcomes in out-of-hospital cardiac arrest: a protocol for a preplanned secondary analysis of the TTM2 trial nork Robba, C, Nielsen, N, Dankiewicz, J, Badenes, R, Battaglini, D, Ball, L, Brunetti, I, Pedro David, W-G, Young, P, Eastwood, G, Chew, MS, Jakobsen, J, Unden, J, Thomas, M, Joannidis, M, Nichol, A, Lundin, A, Hollenberg, J, Lilja, G, Hammond, NE, Saxena, M, Martin, A, Solar, M, Taccone, FS, Friberg, HA, Pelosi, P

“...<strong>Introduction</strong> Mechanical ventilation is a fundamental component in the management of patients post cardiac arrest. However, the ventilator settings and the gas-exchange targets used after cardiac arrest may not be optimal to minimise post-anoxic secondary brain injury. ...”

Cardiac arrest precipitated by succinylcholine in a patient with COVID-19. Comment on Br J Anaesth 2020; 125: e255–7 nork Crockett, DC, Frise, MC, Strachan, JM

Effect of statins on ventricular tachyarrhythmia, cardiac arrest, and sudden cardiac death: a meta-analysis of published and unpublished evidence from randomized trials. nork Rahimi, K, Majoni, W, Merhi, A, Emberson, J

“...We sought to test whether statins reduce the risk of ventricular tachyarrhythmia, cardiac arrest, and sudden cardiac death. METHODS AND RESULTS: We searched MEDLINE, EMBASE, and CENTRAL up to October 2010. ...”

Survival of resuscitated cardiac arrest patients with ST-elevation myocardial infarction (STEMI) conveyed directly to a Heart Attack Centre by ambulance clinicians. nork Fothergill, Rachael T., Watson, Lynne R., Virdi, Gurkamal K., Moore, Fionna P., Whitbread, Mark

“...This study reports survival outcomes for patients resuscitated from out-of-hospital cardiac arrest (OHCA) subsequent to ST-elevation myocardial infarction (STEMI), and who were conveyed directly by ambulance clinicians to a specialist Heart Attack Centre for expert cardiology assessment, angiography and possible percutaneous coronary intervention (PCI)....”
Testu osoa

Prehospital randomised assessment of a mechanical compression device in out-of-hospital cardiac arrest (PARAMEDIC): a pragmatic, cluster randomised trial and economic evaluation nork Gates, S, Lall, R, Quinn, T, Deakin, C, Cooke, M, Horton, J, Lamb, S, Slowther, A, Woollard, M, Carson, A, Smyth, M, Wilson, K, Parcell, G, Rosser, A, Whitfield, R, Williams, A, Jones, R, Pocock, H, Brock, N, Black, J, Wright, J, Han, K, Shaw, G, Blair, L, Marti, J, Hulme, C, McCabe, C, Nikolova, S, Ferreira, Z, Perkins, G

“...Clusters were ambulance service vehicles, which were randomly assigned (approximately 1 : 2) to the LUCAS-2 device or manual CPR.Patients were included if they were in cardiac arrest in the out-of-hospital environment. Exclusions were patients with cardiac arrest as a result of trauma, with known or clinically apparent pregnancy, or aged &lt; 18 years.Patients received LUCAS-2 mechanical chest compression or manual chest compressions according to the first trial vehicle to arrive on scene.Survival at 30 days following cardiac arrest; survival without significant neurological impairment [Cerebral Performance Category (CPC) score of 1 or 2].We enrolled 4471 eligible patients (1652 assigned to the LUCAS-2 device and 2819 assigned to control) between 15 April 2010 and 10 June 2013. ...”

Effect of a strategy of a supraglottic airway device vs tracheal intubation during out-of-hospital cardiac arrest on functional outcome: the AIRWAYS-2 randomized clinical trial nork Benger, J, Kirby, K, Black, S, Brett, S, Clout, M, Lazaroo, M, Nolan, J, Reeves, B, Robinson, M, Scott, L, Smartt, H, South, A, Stokes, E, Taylor, J, Thomas, M, Voss, S, Wordsworth, S, Rogers, C

“...<strong>Importance</strong> The optimal approach to airway management during out-of-hospital cardiac arrest is unknown. <strong>Objective</strong> To determine whether a supraglottic airway device (SGA) is superior to tracheal intubation (TI) as the initial advanced airway management strategy in adults with nontraumatic out-of-hospital cardiac arrest. ...”

Cost-effectiveness of the i-gel supraglottic airway device compared to tracheal intubation during out-of-hospital cardiac arrest: findings from the AIRWAYS-2 randomised controlled trial nork Stokes, EA, Lazaroo, MJ, Clout, M, Brett, SJ, Black, S, Kirby, K, Nolan, JP, Reeves, BC, Robinson, M, Rogers, CA, Scott, LJ, Smartt, H, South, A, Taylor, J, Thomas, M, Voss, S, Benger, JR, Wordsworth, S

“...<p><strong>Aim</strong></p> Optimal airway management during out-of-hospital cardiac arrest (OHCA) is uncertain. Complications from tracheal intubation (TI) may be avoided with supraglottic airway (SGA) devices. ...”

The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database nork McGuigan, PJ, Giallongo, E, Blackwood, B, Doidge, J, Harrison, DA, Nichol, AD, Rowan, KM, Shankar-Hari, M, Skrifvars, MB, Thomas, K, McAuley, DF

“...<p><strong>Background</strong> Hypotension following out-of-hospital cardiac arrest (OHCA) may cause secondary brain injury and increase mortality rates. ...”

Prediction of cardiac arrest in critically ill patients presenting to the emergency department using a machine learning score incorporating heart rate variability compared with the modified early warning score nork Ong, Marcus Eng Hock., Lee Ng, Christina Hui., Goh, Ken., Liu, Nan., Koh, Zhi Xiong., Shahidah, Nur., Zhang, Tongtong., Fook-Chong, Stephanie., Lin, Zhiping.

“...Introduction: A key aim of triage is to identify those with high risk of cardiac arrest, as they require intensive monitoring, resuscitation facilities, and early intervention. ...”
Testu osoa
Testu osoa

Early warning score adjusted for age to predict the composite outcome of mortality, cardiac arrest or unplanned intensive care unit admission using observational vital-sign data: a multicentre development and validation nork Shamout, F, Zhu, T, Clifton, L, Briggs, J, Prytherch, D, Tarassenko, L, Watkinson, P, Clifton, D

“...</p> <p><strong>Participants</strong> Hospitalised patients with electronically documented vital-sign observations</p> <p><strong>Outcome</strong> Composite outcome of unplanned intensive care unit admission, mortality and cardiac arrest.</p> <p><strong>Methods and results</strong> Statistical distributions of vital signs were used to develop an ASEWS to predict the composite outcome within 24 hours. ...”

An international collaborative study to co-produce a patient-reported outcome measure of cardiac arrest survivorship and health-related quality of life (CASHQoL): a protocol for developing the long-form measure nork Haywood, KL, Southern, C, Tutton, E, Swindell, P, Ellard, D, Pearson, NA, Parsons, H, Couper, K, Dainty, KN, Agarwal, S, Perkins, GD

“...<p><strong>Background</strong></p> Current measures of health-related quality of life are neither sufficiently sensitive or specific to capture the complex and heterogenous nature of the recovery and survivorship associated with cardiac arrest. To address this critical practice gap, we plan a mixed-methods study to co-produce and evaluate a new cardiac arrest-specific patient/survivor-reported outcome measure (PROM). ...”