Defining definitions: a Delphi study to develop a core outcome set for conditions of severe maternal morbidity par Schaap, T, Bloemenkamp, K, Deneux-Tharaux, C, Knight, M, Langhoff-Roos, J, Sullivan, E, van den Akker, T

“…From these suggestions, a steering committee distilled critical components (eclampsia:23, amniotic fluid embolism:15, pregnancy-related hysterectomy:11, severe primary postpartum haemorrhage:19, uterine rupture:20, abnormally invasive placentation:12, spontaneous haemoperitoneum in pregnancy:16, and cardiac arrest in pregnancy:10). These components were assessed by the expert panel using a five-point Likert scale, following which a framework for an encompassing definition was constructed. …”

The hazards of gastric lavage for intentional self-poisoning in a resource poor location. par Eddleston, M, Haggalla, S, Reginald, K, Sudarshan, K, Senthilkumaran, M, Karalliedde, L, Ariaratnam, A, Sheriff, M, Warrell, D, Buckley, N

“…Serious complications likely to be due to the lavage were observed, including cardiac arrest and probable aspiration of fluid. Health care workers perceived lavage as being highly effective and often life-saving; there was peer and relative pressure to perform lavage in self-poisoned patients. …”

Bayesian Gaussian processes for identifying the deteriorating patient par Colopy, G

“…Although most of these patients will continue to recover and stabilise, a significant portion will suffer cardiac arrest and/or other clinical emergencies, and readmission into intensive care. …”

Manual centile-based early warning scores derived from statistical distributions of observational vital-sign data par Watkinson, P, Pimentel, M, Clifton, D, Tarassenko, L

“…We assessed the ability of scores to discriminate patients at risk of cardiac arrest, unanticipated intensive care unit admission, or death, each within 24 h of a given vital-sign observation, using metrics including the area under the receiver-operating characteristic curve (AUC).…”

Protocol describing a systematic review and mixed methods consensus process to define the deteriorated ward patient par Malycha, J, Andersen, C, Redfern, OC, Peake, S, Subbe, C, Dykes, L, Phillips, A, Ludbrook, G, Young, D, Watkinson, PJ, Flabouris, A, Jones, D

“…In observational studies evaluating this cohort, proxy outcomes such as unplanned intensive care unit admission, cardiac arrest and death are used. These outcome measures introduce subjectivity and variability, which in turn hinders the development and accuracy of the increasing numbers of electronic medical record (EMR) linked digital tools designed to predict clinical deterioration. …”

Cost effectiveness of perindopril in reducing cardiovascular events in patients with stable coronary artery disease using data from the EUROPA study. par Briggs, A, Mihaylova, B, Sculpher, M, Hall, A, Wolstenholme, J, Simoons, M, Deckers, J, Ferrari, R, Remme, W, Bertrand, M, Fox, K

“…A cost-effectiveness analysis is presented as a function of the risk of a primary event (non-fatal myocardial infarction, cardiac arrest or cardiovascular death) in order to identify people for whom treatment offers greatest value for money. …”

Multidisciplinary crisis simulations: the way forward for training surgical teams. par Undre, S, Koutantji, M, Sevdalis, N, Gautama, S, Selvapatt, N, Williams, S, Sains, P, McCulloch, P, Darzi, A, Vincent, C

“…Crisis scenarios such as difficult intubation, hemorrhage, or cardiac arrest were simulated. Technical and non-technical skills (leadership, communication, team skills, decision making, and vigilance), were assessed by clinical experts and by two psychologists using relevant technical and human factors rating scales. …”

Ergonomic risk assessment of musculoskeletal disorders during chest compression at kneeling, standing and step-on-stool position in rescuer performing cardiopulmonary resuscitation par Ghani, Nurul Husna Abd.

“…Methods: A cross-sectional simulated-manikin study of in-hospital cardiac arrest was conducted among medical personnel of emergency department of university hospital located in Kelantan, Malaysia. …”
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Quantitative Electroencephalogram Trends Predict Recovery in Hypoxic-Ischemic Encephalopathy* par Ghassemi, Mohammad M, Amorim, Edilberto, Alhanai, Tuka, Lee, Jong W, Herman, Susan T, Sivaraju, Adithya, Gaspard, Nicolas, Hirsch, Lawrence J, Scirica, Benjamin M, Biswal, Siddharth, Moura Junior, Valdery, Cash, Sydney S, Brown, Emery N, Mark, Roger G, Westover, M Brandon

“…OBJECTIVES: Electroencephalogram features predict neurologic recovery following cardiac arrest. Recent work has shown that prognostic implications of some key electroencephalogram features change over time. …”
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Design optimization of oxygenated fluid pump par Piazzarolo, Bruno Aiala

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A safer spin par Chew, Audrey Xin Ying, Chia, Nicholas Wei De, Siew, Ming Li, Wee, Hong Liang

“…If left untreated, ER may cause acute kidney injury, cardiac arrest, and loss of limb, all of which can eventually lead to death. …”
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A retrospective study of physiological observation-reporting practices and the recognition, response, and outcomes following cardiopulmonary arrest in a low-to-middle-income countr... par De Silva, A, Sujeewa, J, De Silva, N, Rathnayake, R, Vithanage, L, Sigera, P, Munasinghe, S, Beane, A, Stephens, T, Athapattu, P, Jayasinghe, K, Dondorp, A, Haniffa, M

“…One hundred and fifty adult patients who had cardiac arrests and were reported to a nurse responder were included in the study.…”

Impact of cardiometabolic multimorbidity and ethnicity on cardiovascular/renal complications in patients with COVID-19 par Norris, T, Razieh, C, Zaccardi, F, Yates, T, Islam, N, Gillies, CL, Chudasama, YV, Rowlands, AV, Davies, MJ, McCann, GP, Banerjee, A, Lam, CSP, Docherty, AB, Openshaw, PJ, Baillie, JK, Semple, MG, Lawson, CA, Khunti, K, Horby, P

“…Logistic models were used to explore associations between baseline patient ethnicity, cardiometabolic conditions and multimorbidity (0, 1, 2, >2 conditions), and in-hospital cardiovascular complications (heart failure, arrhythmia, cardiac ischaemia, cardiac arrest, coagulation complications, stroke), renal injury and death. …”

Long-term clinical outcomes in patients with an acute ST-segment-elevation myocardial infarction stratified by angiography-derived index of microcirculatory resistance par Kotronias, RA, Terentes-Printzios, D, Shanmuganathan, M, Marin, F, Scarsini, R, Bradley-Watson, J, Langrish, JP, Lucking, AJ, Choudhury, R, Kharbanda, RK, Garcia-Garcia, HM, Channon, KM, Banning, AP, De Maria, GL

“…The combination of all-cause mortality, resuscitated cardiac arrest and new heart failure was the primary endpoint. …”

A comparison of the ability of the National Early Warning Score and the National Early Warning Score 2 to identify patients at risk of in-hospital mortality: A multi-centre databas... par Pimentel, MAF, Redfern, O, Gerry, S, Collins, GS, Malycha, JL, Prytherch, D, Schmidt, PE, Smith, GS, Watkinson, PJ

“…Secondary outcomes included unanticipated intensive care unit admission or cardiac arrest within 24 h of a vital signs observation. …”

Global patient outcomes after elective surgery: Prospective cohort study in 27 low-, middle- and high-income countries par International Surgical Outcomes Study group, Gardiner, M

“…Mortality following complications ranged from 2.4% for pulmonary embolism to 43.9% for cardiac arrest. A total of 4360 (9.7%) patients were admitted to a critical care unit as routine immediately after surgery, of whom 2198 (50.4%) developed a complication, with 105 (2.4%) deaths. …”

Machine learning for the detection of clinical deterioration on hospital wards par Shamout, F

“…In this thesis, we propose improved and generalisable risk assessment algorithms, that can continuously alert for deterioration preceding the composite outcome of unplanned intensive care unit admission, cardiac arrest, and mortality. We develop and validate three statistical and machine learning models using large-scale datasets from two independent centres: Oxford University Hospitals and Portsmouth NHS Hospitals within the HAVEN database. …”

Data fusion models for detection of vital-sign deterioration in acutely ill patients par Khalid, S

“…<p>Vital signs can indicate patient deterioration prior to adverse events such as cardiac arrest, emergency admission to the intensive care unit (ICU), or death. …”

Effect of nitrite on the electroencephalographic activity in the healthy brain par Franko, E, Ezra, M, Crockett, D, Joly, O, Pattinson, K

“…The use of nitrite is, therefore, being evaluated widely to reduce the brain injury in conditions resulting in cerebral hypoxia, such as cardiac arrest, ischaemic stroke or subarachnoid haemorrhage. …”

Prognostic significance of ventricular arrhythmias in 13 444 patients with acute coronary syndrome: A retrospective cohort study based on routine clinical data (NIHR Health Informa... par Sau, A, Kaura, A, Ahmed, A, Patel, KHK, Li, X, Mulla, A, Glampson, B, Panoulas, V, Davies, J, Woods, K, Gautama, S, Shah, AD, Elliott, P, Hemingway, H, Williams, B, Asselbergs, FW, Melikian, N, Peters, NS, Shah, AM, Perera, D, Kharbanda, R, Patel, RS, Channon, KM, Mayet, J, Ng, FS

“…<strong>Background</strong> A minority of acute coronary syndrome (ACS) cases are associated with ventricular arrhythmias (VA) and/or cardiac arrest (CA). We investigated the effect of VA/CA at the time of ACS on long‐term outcomes. …”