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The Degradation Product of Ramipril Is Potentially Carcinogenic, Genotoxic and Mutagenic
Published 2023-02-01“…We intended to check whether its formation and presence in final dosage forms could pose a cancer risk to humans who are treated with RAM due to cardiological indications. The carcinogenicity of this compound was evaluated with respect to two mechanisms: a potential direct DNA-damage and indirect toxicity, secondary to forming mutagenic N-nitroso metabolites. (2) Methods: Firstly, a forced ageing test under dry air was conducted for pure RAM in order to induce its degradation. …”
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A PERSONALIZED APPROACH TO ASSESSING THE RISK OF REPEAT CARDIOVASCULAR EVENT AND CHRONIC KIDNEY DISEASE IN PATIENTS WITH MYOCARDIAL INFARCTION AND ACUTE KIDNEY INJURY
Published 2023-09-01“…Develop a calculator - a risk meter for repeated CCC.Materials and methods: the study was performed in the Altai Regional Cardiological Dispensary. 193 patients with MI and PCI (percutaneous coronary intervention) were included, divided into 2 groups: the first - 123 patients aged 62.8±1.1 years with MI and AKI, the second - 70 patients without AKI, age 61.3± 1.6 years. …”
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Results of different kinds of carotid endarterectomy in patients with and without type 2 diabetes mellitus
Published 2022-02-01Get full text
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Emergency Glomus-Sparing Carotid Endarterectomy According to A.N. Kazantsev
Published 2021-01-01Get full text
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Prognostic factors of children’s acute lymphoblastic leukemia therapy in Moscow—Berlin protocols
Published 2022-11-01Get full text
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