Castle man disease: a case report and review of the literature by Mounir Kettani, Nabil Touiheme, Hicham Attifi, Mounir Hmidi, Ali Boukhari, Mohamed Zalagh, Abdelhamid Messary

“…The Castleman disease (CD) is a rare disease of unknown etiology, characterized histologically by angiofollicular lymphoid hyperplasia. …”
Get full text

A Rare Case of HHV-8 Associated Hemophagocytic Lymphohistiocytosis in a Stable HIV Patient by Nonso Osakwe, Diane Johnson, Natalie Klein, Dalia Abdel Azim

“…This is a rare case that reports HLH associated with human herpes virus-8 (HHV-8) associated multicentric Castleman disease in a stable HIV patient. Case Presentation. …”
Get full text

TAFRO Syndrome and COVID-19 by Misato Tane, Hideki Kosako, Takashi Sonoki, Hiroki Hosoi

“…We reviewed the literature about the association between TAFRO syndrome or Castleman disease and COVID-19 or vaccination against it. …”
Get full text

POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, skin lesions) syndrome: a South America's report POEMS (polineuropatia, organomegalia, endocrinopatia, proteína M, a... by Ana Claudia Celestino Leite, Osvaldo J.M. Nascimento, Marco Antonio Lima, Maria José Andrada-Serpa

“…Several other associated condictions such as sclerotic bone lesions, Castleman disease, low-grade fever, edema and hematologic disorders are usually seen. …”
Get full text

HHV8/EBV Coinfection Lymphoproliferative Disorder: Rare Entity with a Favorable Outcome by Dhouha Bacha, Beya Chelly, Houda Kilani, Lamia Charfi, Amel Douggaz, Samia Chatti, Emna Chelbi

“…In the adjacent lymph node parenchyma, some germinal centers mimicked Castleman disease. In this case, the differential diagnosis was discussed with an early stage of large B-cell lymphoma arising in HHV8-associated multicentric Castleman disease. …”
Get full text

Extracavitary tumor after primary effusion lymphoma: relapse or second distinct lymphoma? by Emmanuelle Boulanger, Véronique Meignin, Philippe V. Afonso, Renan Duprez, Eric Oksenhendler, Félix Agbalika, Antoine Gessain

“…HHV-8-associated solid lymphomas which develop in extracavitary sites during the course of primary effusion lymphoma (PEL) could represent the relapse of original PEL tumors in different anatomical sites, or newly occurring distinct HHV-8-associated lymphomas, such as multicentric Castleman disease-related microlymphomas. HHV-8 episome clonality might help identify which event takes place.…”
Get full text

Case report: The stroma-rich variant of Castleman’s disease of hyaline-vascular type with atypical stromal cell proliferation and malignant potential: An exceptional rare case occu... by Xiaoxin Shi, Mengying Liao, Xiaomin Yin, Yaoli Chen, Chuqiang Huang, Weihua Yin, Jian Li, Jian Li

“…The stroma-rich variant of Castleman disease of hyaline-vascular type (SR-HVCD) is characterized by interfollicular proliferation of the fibroblastic, myofibroblastic, and/or histiocytic-derived stromal cells, occurred in a background of Castleman disease of hyaline-vascular type (HVCD). …”
Get full text

A Delayed Diagnosis: Conflicting Investigation Results Should Be Challenged by D. Mital, V. Desai

“…We present a case where a diagnosis of advanced HIV led to many other diagnoses but more importantly life-threatening multivariant Castleman's disease which is rare and was successfully treated. …”
Get full text

Hemangioma glomeruloide e a síndrome POEMS: relato de dois casos e revisão da literatura Glomeruloid hemangioma in POEMS syndrome: a report on two cases and a review of the literat... by Thiago Jeunon, Ana Luisa Bittencourt Sampaio, Ricardo C Caminha, Carlos Umberto da Cunha Reis, Cassio Dib

“…The final diagnosis in this case was POEMS syndrome associated with Castleman's disease.…”
Get full text

Head and neck follicular dendritic cell sarcoma: disease associations and treatment review by Asha'ari, Zamzil Amin, Suhaimi, Y., Raja Lope Ahmad, Raja Ahmad Al'konee

“…Currently, of less than 50 cases of head and neck follicular dendritic cell (FDC) sarcoma reported in the literature, 5 have been found to occur in the background of Castleman disease.We report another case of head and neck FDC sarcoma with emphasise on its associated lesions and review the outcome of treatment from the existing cases in the literature.…”
Get full text

Oral Paraneoplastic Pemphigus: A Scoping Review on Pathogenetic Mechanisms and Histo-Serological Profile by Domenico De Falco, Sabrina Messina, Massimo Petruzzi

“…Key findings revealed that PNP is often diagnosed before the neoplasm, with Follicular variant Non-Hodgkin Lymphoma and Castleman Disease being the most common associations. Histopathological analysis showed suprabasal acantholysis and inflammation, and serological tests identify a comprehensive autoantibody panel, underscoring the need for standardized diagnostic criteria and improved serological testing.…”
Get full text

Targeting Interleukin-6: All the Way to Treat Autoimmune and Inflammatory Diseases by Toshio Tanaka, Tadamitsu Kishimoto

“…Indeed, clinical trials of tocilizumab, a humanized anti-IL-6 receptor antibody have verified its efficacy and tolerable safety for patients with rheumatoid arthritis, Castleman's disease and systemic juvenile idiopathic arthritis, resulting in approval of this innovative biologic for treatment of these diseases. …”
Get full text

A Case of Paraneoplastic Pemphigus with Malignant Thymoma and Obliterated Bronchiolitis by WANG Rui, WANG Mingyue

“…Paraneoplastic pemphigus (PNP) is a rare and life-threatening autoimmune blistering disease characterized by severe mucosal erosions and polymorphous cutaneous eruptions associated with lymphoproliferative neoplasmas. Castleman's disease, non-Hodgkin's lymphoma, thymoma, follicular dendritic cell sarcoma and chronic lymphocytic leukemia are the commonly associated neoplasmas in PNP, whereas malignant thymoma is rare. …”
Get full text

PB2708: SYMPTOM BURDEN AND ITS IMPACT ON DAILY LIFE IN PATIENTS WITH IDIOPATHIC MULTICENTRIC CASTLEMAN’S DISEASE (IMCD): AN EXPLORATORY ANALYSIS OF THE SURVEY’S INTERNAL CONSTRUCT... by Matt Franklin, Francis Shupo, Emily Jones, Nicola Mason, Grace Wayi-Wayi, Karan Kanhai, Natasa Zibelnick, Mileva Repasky, Kelly Makarounas-Kirchmann, Sudipto Mukherjee, John Brazier

Get full text

Anasarca, Fever, Thrombocytopenia, Organomegaly, and Multiorgan Failure in a 24-Year-Old Pregnant Woman by Guillaume Morel, Joy Mootien, Philippe Guiot, Khaldoun Kuteifan

“…TAFRO syndrome is a distinct idiopathic multicentric Castleman disease characterized by the association of thrombocytopenia, anasarca, fever, reticulin fibrosis, and organomegaly. …”
Get full text

Kaposi's Sarcoma-Associated Herpesvirus-Related Solid Lymphoma Involving the Heart and Brain by Jason R. Andrews, Yoon Andrew Cho-Park, Judith Ferry, Jeremy S. Abramson, Gregory K. Robbins

“…The disorders most strongly linked to KSHV are multicentric Castleman's Disease (MCD), primary effusion lymphoma, and diffuse large B-cell lymphomas. …”
Get full text

Unicentric Castleman’s Disease Masquerading Pancreatic Neoplasm by Saurabh Jain, Souvik Chatterjee, Jyoti Ranjan Swain, Pritha Rakshit, Partha Chakraborty, Santanu Sinha

“…Here we are reporting a case of retropancreatic Castleman's disease masquerading as retroperitoneal neoplasm in a 46-year-old male patient.…”
Get full text

A Rare Case of Castleman Variant of POEMS Syndrome by Gevesh Chand Dewangan, Sunny Singhal, Rishav Bansal, Avinash Chakrawarty

“…A lymph node biopsy showed Castleman disease, and the computed tomography scan was suggestive of multiple osteosclerotic lesions. …”
Get full text

Non-detection of human herpesvirus 8 (HHV-8) DNA in HHV-8-seropositive blood donors from three Brazilian regions. by José Eduardo Levi, Maria Claudia Nascimento, Laura Masami Sumita, Vanda Akico Ueda Fick de Souza, Wilton S Freire, Philippe Mayaud, Claudio S Pannuti

“…Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is the etiologic agent of all forms of Kaposi's sarcoma, primary effusion lymphoma and the plasmablastic cell variant of multicentric Castleman disease. In endemic areas of sub-Saharan Africa, blood transfusions have been associated with a substantial risk of HHV-8 transmission. …”
Get full text

Pathophysiology, Treatment, and Prognosis of Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Failure, and Organomegaly (TAFRO) Syndrome: A Review by Takuya Kakutani, Riko Kamada, Yotaro Tamai

“…It is sometimes considered a special subtype of idiopathic multicentric Castleman disease (iMCD) because lymph node biopsies often reveal the pathology findings seen in iMCD. …”
Get full text