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An investigation into the cytotoxic effects of microbubbles and their constituents on osteosarcoma and bone marrow stromal cells
Publicado em 2023“…DSPC:PEG40S microbubbles had greater inhibitory effects on cell metabolism and growth than DBPC:DSPE-PEG<sub>2000</sub> microbubbles, with PEG40S found to be the principle inhibitory component. …”
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182
An Examination of Differentially-Expressed Genes from Oil Palm Embryogenic and Non-Embryogenic Cultures
Publicado em 2003“…Most of the other genes were found to be involved in cell metabolism and proliferation, which leads to an increase in the expression of genes involved in namely, protein synthesis and signal transduction pathways. …”
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183
Effect of selective nutrients in medium on human skin fibroblasts growth and metabolism
Publicado em 2008“…A thorough understanding of cell metabolism and physiology is necessary for medium optimization, where cells can improve their yield and increase their efficiency of medium utilization or minimize the formation of toxic by-products. …”
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184
The role of the PD-1 pathway in the tumor microenvironment
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185
KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer
Publicado em 2017“…In addition, loss of KEAP1 altered cell metabolism to allow cells to proliferate in the absence of MAPK signaling. …”
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186
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Metabolic Pathway Alterations that Support Cell Proliferation
Publicado em 2013“…Proliferating cells adapt metabolism to support the conversion of available nutrients into biomass. How cell metabolism is regulated to balance the production of ATP, metabolite building blocks, and reducing equivalents remains uncertain. …”
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188
Cellular responses of normal human osteoblasts to multiple environmental stressors in vitro / Aisha Mohd Din
Publicado em 2017“…The response to continuous orbital fluid shear stress (OFSS), moderate hypothermia (35°C) and moderate hyperthermia (39°) in this study demonstrated an anabolic effect on Normal Human Osteoblast (NHOst) cells where the cell metabolism, differentiation and proliferation was either promoted or retained. …”
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189
The cytotoxic effect and glucose uptake modulation of Baeckea frutescens on breast cancer cells
Publicado em 2019“…These findings suggest a new role of B. frutescens in cancer cell metabolism…”
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190
Study on surface hydrogenated Ti6Al4V alloy for orthopedic implants
Publicado em 2024“…Moreover, reduced ROS production was observed around the H–Ti6Al4V alloys, confirming that hydrogenation could effectively counteract the ROS generated during cell metabolism and indirectly impede the inflammatory response around the prosthesis, thereby rendering it a promising metallic implant for the treatment of bone defects.…”
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191
Increased DNA methylation variability in type 1 diabetes across three immune effector cell types
Publicado em 2018“…Integration with cell type-specific gene regulatory circuits highlight pathways involved in immune cell metabolism and the cell cycle, including mTOR signalling. …”
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192
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
Publicado em 2014“…In the conventional view of mammalian cell metabolism, AcCoA is primarily generated from glucose-derived pyruvate through the citrate shuttle and ATP citrate lyase in the cytosol. …”
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193
Monitoring biological functions of cultured tissues using microdialysis
Publicado em 2007“…</p> <p>Apart from cell metabolic activities, cell and tissue biological functions were investigated for the development of microdialysis for monitoring purposes. …”
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194
Postharvest qualities and metabolic responses of hydro- cooled rockmelon (Cucumis melo L. reticulatus cv Glamour) after differential storage durations
Publicado em 2018“…Noticeably, less accumulation of sucrose during advanced cold storage in control and 1/2 CT hydro-cooled rockmelon rind might reduce the cell metabolism and fruit resistibility in response to cold storage since it influences the cell structural support and protection against reactive oxygen species (ROS). …”
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195
Non-invasive nanosensor monitoring of mRNA expression for regenerative medicine application
Publicado em 2017“…Labeling concentration was assessed and optimized to ensure minimal influence over cell metabolism and proliferation rate. Meanwhile, multi-potency of labeled mesenchymal stem cells was minorly affected towards three differentiation lineages: adipogenesis, osteogenesis and chondrogenesis. …”
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196
Developing liquid chromatography-mass spectrometry strategies for investigating energy metabolism with application to isocitrate dehydrogenase mutations in cancer
Publicado em 2015“…The methods developed enable the investigation into the regio- and stereo- chemistry of TCA cycle and associated metabolites and are powerful tools for investigating cancer cell metabolism.…”
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197
Isolation and characterisation of anti-diabetic pharmacological activities of phytoestrogens and components of Moringa peregrina (Forssk) Fiori
Publicado em 2016“…Real-time monitoring of cell metabolism by a Seahorse XF-24 auto analyser after two hours incubation with the three chosen compounds revealed that maximal respiration, non-mitochondrial respiration and spare respiratory capacity have trended towards an increase with ȕ-sitosterol and3-O-ethyl 4-[(α-Lrhamnosyloxy) benzyl] thiocarbamate (E) treatments compared to control. …”
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198
In-vivo and in-vitro study of mechanism of action of 4 hydroxyisoleucine as an amino acid derived from fenugreek seed with anti-diabetic and properties
Publicado em 2014“…Real time monitoring of cell metabolism by Seahorse XF-24 autoanalyser after 24 hours incubation with 4-hydroxyisoleucine and isoleucine revealed that both 4-hydroxyisoleucine and isoleucine activities are strongly dependent on mitochondrial respiration but 4-hydroxyisoleucine significantly up-regulates glycolysis which is not affected by isoleucine. …”
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199
In vitro study of various factors in isolation, expansion and differentiation of mesenchymal stem cells from human umbilical cord
Publicado em 2012“…Student`s t-test for evaluation of cell metabolism with WST-1 showed that the quality of the expanded cells in α-MEM/GL group was significantly higher (P<0.001) than DMEM/F12 group. …”
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200
Aspects of the metabolism of microorganisms
Publicado em 1941“…</li> </ol> <p>Many pure vitamins, amino-acids and other compounds of importance in general cell metabolism were tested for ability to stimulate the growth of strain A; only those mentioned above were active.…”
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