Optimized PDMs microfluidic biochips for ESC pluripotency maintenance and cardiac differentiation by Ang, Wee Tong

“…However, due to the intrinsic PDMS surface hydrophobicity, it inhibits cell adhesion and therefore surface modification is needed for effective cell adhesion. …”
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Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin-catenin complexes in human colon carcinoma cells. by Efstathiou, J, Noda, M, Rowan, A, Dixon, C, Chinery, R, Jawhari, A, Hattori, T, Wright, N, Bodmer, W, Pignatelli, M

“…No change in either cell adhesion or in the expression of E-cadherin, the catenins, and APC was detected in SW480 cells. …”

The eighth FIII domain of human fibronectin promotes integrin alpha5beta1 binding via stabilization of the ninth FIII domain. by Altroff, H, van der Walle, C, Asselin, J, Fairless, R, Campbell, I, Mardon, H

“…Here we investigate the function of the eighth FIII domain in integrin-mediated cell adhesion using a wide range of methods, including biochemical, biological, and biophysical assays of integrin binding, cell adhesion, and protein denaturation. …”

Influence of receptor lateral mobility on adhesion strengthening between membranes containing LFA-3 and CD2. by Chan, P, Lawrence, M, Dustin, M, Ferguson, L, Golan, D, Springer, T

“…We have used an in vitro model system of glass-supported planar membranes to study the effects of lateral mobility of membrane-bound receptors on cell adhesion. Egg phosphatidylcholine (PC) bilayers were reconstituted with two anchorage isoforms of the adhesion molecule lymphocyte function-associated antigen 3 (LFA-3). …”

Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity. by Newham, P, Craig, SE, Seddon, G, Schofield, N, Rees, A, Edwards, R, Jones, E, Humphries, M

“…A related CAM, mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is recognized by alpha4beta7 but is a poor ligand for alpha4beta1. …”

ZNF185 is a p63 target gene critical for epidermal differentiation and squamous cell carcinoma development by Smirnov, A, Lena, A, Cappello, A, Panatta, E, Anemona, L, Bischetti, S, Annicchiarico-Petruzzelli, M, Mauriello, A, Melino, G, Candi, E

“…However, limited knowledge exists on the relevant cell–cell adhesion molecules involved in physiological epithelial formation. …”

Relationship between duration of brain death and hemodynamic (in)stability on progressive dysfunction and increased immunologic activation of donor kidneys. by van der Hoeven, J, Molema, G, Ter Horst, G, Freund, R, Wiersema, J, van Schilfgaarde, R, Leuvenink, H, Ploeg, R

“…Organ function was studied by monitoring serum creatinine, lactate dehydrogenase (LDH), lactate, and total protein content. Expression of cell adhesion molecules [intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1)] and the influx of leukocytes in the kidney assessed the immunologic status of the kidney. …”

Self-assembled monolayer based micropatterns and their application in cell patterning by Ahuja, Tanvi

“…Both types of micropatterns enable good cell adhesion behavior, exhibiting their biocompatibility, and hence, emphasizing their potential for numerous applications in biomedical devices.…”
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Rap1 regulates the formation of E-cadherin-based cell-cell contacts. by Hogan, C, Serpente, N, Cogram, P, Hosking, C, Bialucha, C, Feller, S, Braga, V, Birchmeier, W, Fujita, Y

“…We conclude that Rap1 plays a vital role in the establishment of E-cadherin-based cell-cell adhesion.…”

The talin-tail interaction places integrin activation on FERM ground. by Campbell, I, Ginsberg, M

“…Integrins are essential receptors for the development and functioning of multicellular animals because they mediate cell migration and cell adhesion, and regulate cell proliferation and apoptosis. …”

The leucocyte β2 (CD18) integrins : the structure, functional regulation and signalling properties by Tan, Suet Mien

“…Their ability to migrate into tissues and organs is dependent on cell adhesion molecules. The integrins are a family of heterodimeric transmembrane cell adhesion molecules that are also signalling receptors. …”
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Structural studies on oligosaccharides from mammalian glycoproteins by Field, M, Field, Mark Christian

“…The saccharide from these glycolipids influences neural cell adhesion …”

Induction of organ dysfunction and up-regulation of inflammatory markers in the liver and kidneys of hypotensive brain dead rats: a model to study marginal organ donors. by van der Hoeven, J, Ploeg, R, Postema, F, Molema, I, de Vos, P, Girbes, A, van Suylichem, P, van Schilfgaarde, R, Ter Horst, G

“…Tissue activation of liver and kidney was assessed by staining of immediate early gene products (IEG: FOS, JUN), and inflammatory markers; cell adhesion molecules (Intercellular adhesion molecule-1, vascular cell adhesion molecule-1), leukocyte infiltrates (CD45, T cell receptor, CD8, CD4), and MHC class II. …”

Endothelial cell responses in terms of adhesion, proliferation, and morphology to stiffness of polydimethylsiloxane elastomer substrates by Ataollahi, F., Pramanik, S., Moradi, A., Dalilottojari, A., Pingguan-Murphy, Belinda, Wan Abas, Wan Abu Bakar, Abu Osman, Noor Azuan

“…The results also revealed that stiffer substrates promoted endothelial cell adhesion and proliferation and also induced spread morphology in the endothelial cells compared with lesser stiff substrates. …”

Effect of GuizhiShaoyaoZhimuTang (桂枝芍药知母汤）and its components on the LFA-1 mediated leukocyte adhesion to ICAM-1. by Lau, Jasmine Cai Ying.

“…Inflammation is dependent on many mechanisms, one of them being LFA-1/ICAM-1 interaction that causes white blood cell adhesion and eventually, white blood cell recruitment and extravasation that aggravates the inflammation of the joints in RA. …”
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Design of nanofiber-based platform for leukemia stem cell capture. by Ruchi.

“…Therefore, this study will include the fabrication of the PDMS platform with CAD designs to illustrate the platform assembly, preparation of nanofibers for the channel and experiments to analyze cell adhesion to various surfaces and coatings and effect of flow rate or shear stress on the adhesion of the suspension cells. …”
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Structural basis of Latrophilin-FLRT interaction by Jackson, V, del Toro, D, Ordaz, M, Roversi, P, Harlos, K, Klein, R, Seiradake, E

“…The N-terminal region binds the endogenous cell adhesion molecule FLRT, a major regulator of cortical and synapse development. …”

CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesis. by Bastos, R, Penate, X, Bates, M, Hammond, D, Barr, F

“…Cells expressing a CYK4 GAP mutant had defects in cytokinesis and showed elevated staining for the cell adhesion marker vinculin. These defects could be rescued by depletion of ARHGEF7 and p21-activated kinase, Rac1-specific effector proteins required for cell adhesion. …”

Insulin receptor substrate protein 53kDa (IRSp53) is a negative regulator of myogenic differentiation by Misra, Ashish, George, Bhawana, Rajmohan, Rajamuthiah, Jain, Neeraj, Wong, Ming Hwa, Kambadur, Ravi, Thanabalu, Thirumaran

“…Over-expression of IRSp53 in C2C12 cells led to induction of filopodia and decrease in cell adhesion, concomitantly with inhibition of myogenic differentiation. …”
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Investigation of cellular changes on blood cells relevant for the destabilization of blood flow by Stephanie.

“…In conclusion, depletion interaction is a significant determinant in red blood cell – endothelial cell adhesion, electrostatic repulsion is the key nonspecific force governing cell – cell interaction, and deformability reduction alters cell rheological properties which in turn reduce red blood cell – endothelial cell adhesion.…”
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