Characterization of Non-Cholesterol Sterols in Microglia Cell Membranes Using Targeted Mass Spectrometry by Ilijana Begcevic Brkovic, Madlen Reinicke, Soroth Chey, Ingo Bechmann, Uta Ceglarek

“…Background: Non-cholesterol sterols, as well as plant sterols, cross the blood–brain barrier and, thus, can be incorporated into cell membranes, affecting the cell’s inflammatory response. …”
Get full text

Microfluidics Approach to the Mechanical Properties of Red Blood Cell Membrane and Their Effect on Blood Rheology by Claudia Trejo-Soto, Guillermo R. Lázaro, Ignacio Pagonabarraga, Aurora Hernández-Machado

“…In this article, we describe the general features of red blood cell membranes and their effect on blood flow and blood rheology. …”
Get full text

Tumor cell membrane-coated continuous electrochemical sensor for GLUT1 inhibitor screening by Jiaqian Zhao, Yuqiao Liu, Ling Zhu, Junmin Li, Yanhui Liu, Jiarui Luo, Tian Xie, Dajing Chen

“…With current analysis techniques, it is difficult to accurately monitor the GLUT1 inhibitory effect of drug molecules in real-time. We developed a cell membrane-based glucose sensor (CMGS) that integrated a hydrogel electrode with tumor cell membranes to monitor GLUT1 transmembrane transport and screen for GLUT1 inhibitors in traditional Chinese medicines (TCMs). …”
Get full text

The influence of virus infection on the extracellular pH of the host cell detected on cell membrane by Hengjun Liu, Hisataka Maruyama, Taisuke Masuda, Ayae Honda, Fumihito Arai

“…The sensor was adhered to cell membrane for extracellular pH measurement. The results showed that the multiplication of influenza virus in host cell decreased extracellular pH of the host cell by 0.5–0.6 in 4 hours after the virus bound to the cell membrane, compared to that in uninfected cells. …”
Get full text

Influence of changes in microbial cell membrane composition on isotopic fractionation of nitrate during denitrification by Wunderlich Anja, Heipieper Hermann J., Elsner Martin, Einsiedl Florian

“…Denitrifying bacteria thus may express less negative ε15N-NO3- when they are exposed to environmental stress that changes their cell membrane composition.…”
Get full text

Cell Membrane Features as Potential Breeding Targets to Improve Cold Germination Ability of Seeds by Lakhvir Kaur Dhaliwal, Rosalyn B. Angeles-Shim

“…Low temperature stress, in particular, primarily and effectively affects the structure, composition and properties of cell membranes, which ultimately disturbs cellular homeostasis. …”
Get full text

Selective Chemical Activation of Piezo1 in Leukemia Cell Membrane: Single Channel Analysis by Valeria Vasileva, Elena Morachevskaya, Anastasia Sudarikova, Yuri Negulyaev, Vladislav Chubinskiy-Nadezhdin

“…Extracellular application of 0.5–1 µM Yoda1 effectively stimulated single Piezo1 currents in the cell membrane.…”
Get full text

Precise Deposition of Polydopamine on Cancer Cell Membrane as Artificial Receptor for Targeted Drug Delivery by Hoda Safari Yazd, Yu Yang, Long Li, Lu Yang, Xiaowei Li, Xiaoshu Pan, Zhuo Chen, Jianhui Jiang, Cheng Cui, Weihong Tan

“…In this study, we use high K+ and high H2O2 of the tumor microenvironment (TME) to produce polydopamine only on living cancer cell membrane. Owing to the significant reactivity of polydopamine with amino groups, e.g., the amino group of proteins, polydopamine can deposit on tumor cells and act as “artificial receptors” for targeted delivery of anticancer drugs with amino groups, in other words, amino-containing drugs and protein drugs.…”
Get full text

Mechanisms of PDZ domain scaffold assembly illuminated by use of supported cell membrane sheets by Simon Erlendsson, Thor Seneca Thorsen, Georges Vauquelin, Ina Ammendrup-Johnsen, Volker Wirth, Karen L Martinez, Kaare Teilum, Ulrik Gether, Kenneth Lindegaard Madsen

“…Here, we investigate assembly of PDZ scaffolds using supported cell membrane sheets, a unique experimental setup enabling direct access to the intracellular face of the cell membrane. …”
Get full text

Quantitative Analysis of the Membrane Affinity of Local Anesthetics Using a Model Cell Membrane by Wanjae Choi, Hyunil Ryu, Ahmed Fuwad, Seulmini Goh, Chaoge Zhou, Jiwook Shim, Masahiro Takagi, Soonjo Kwon, Sun Min Kim, Tae-Joon Jeon

“…Local anesthesia is a drug that penetrates the nerve cell membrane and binds to the voltage gate sodium channel, inhibiting the membrane potential and neurotransmission. …”
Get full text

A bioelectric model of carcinogenesis, including propagation of cell membrane depolarization and reversal therapies by Joao Carvalho

“…This work fits in the latter hypothesis, proposing the bioelectric field, in particular the cell membrane polarization state, and ionic exchange through ion channels and gap junctions, as an important mechanism of cell communication and tissue organization and regulation. …”
Get full text

Reovirus Forms Neo-Organelles for Progeny Particle Assembly within Reorganized Cell Membranes by Isabel Fernández de Castro, Paula F. Zamora, Laura Ooms, José Jesús Fernández, Caroline M.-H. Lai, Bernardo A. Mainou, Terence S. Dermody, Cristina Risco

“…These findings suggest that cell membranes within reovirus inclusions form a scaffold to coordinate viral replication and assembly. …”
Get full text

Increasing roughness of the human breast cancer cell membrane through incorporation of gold nanoparticles by Lara-Cruz C, Jiménez-Salazar JE, Ramón-Gallegos E, Damian-Matsumura P, Batina N

“…Keywords: gold nanoparticles uptake, MCF-7 cells, membrane roughness, atomic force microscopy, confocal laser scanning microscopy…”
Get full text

Fluorescent Lipids: Functional Parts of Fusogenic Liposomes and Tools for Cell Membrane Labeling and Visualization by Christian Kleusch, Bernd Hoffmann, Nils Hersch, Agnes Csiszár, Rudolf Merkel

“…Here, the fluorescent molecules have two consecutive functions: First, they trigger rapid membrane fusion between cellular plasma membranes and the lipid bilayers of their carrier particles, so called fusogenic liposomes, and second, after insertion into cellular membranes these molecules enable fluorescence imaging of cell membranes and membrane traffic processes. We tested the fluorescent derivatives of the following essential membrane lipids for membrane fusion: Ceramide, sphingomyelin, phosphocholine, phosphatidylinositol-bisphosphate, ganglioside, cholesterol, and cholesteryl ester. …”
Get full text

The clinical regimens and cell membrane camouflaged nanodrug delivery systems in hematologic malignancies treatment by Yuanyuan Liu, Shanwu Yu, Yixiang Chen, Zhihong Hu, Lingling Fan, Gaofeng Liang

Subjects: Get full text

Hyperthermic potentiation of cisplatin by magnetic nanoparticle heaters is correlated with an increase in cell membrane fluidity by Alvarez-Berrios MP, Castillo A, Mendez J, Soto O, Rinaldi C, Torres-Lugo M

“…This, in turn, can increase the passive transport of the drug through the cell membrane. Our results did not show statistically significant differences in surviving fractions for cells treated concomitantly with magnetic fluid hyperthermia and cDDP, in the presence or absence of copper. …”
Get full text

Analyzing receptor assemblies in the cell membrane using fluorescence anisotropy imaging with TIRF microscopy. by Miklos Erdelyi, Joseph Simon, Eric A Barnard, Clemens F Kaminski

“…Receptor monomers and homo-dimers in the cell membrane can be analyzed quantitatively and for homo-dimers only a single fluorescent marker is needed, thus suppressing ambiguities that arise in alternative assays, which require multiple label moieties and which are thus subject to stoichiometric uncertainty.…”
Get full text

Structure of a Sialo-Oligosaccharide from Glycophorin in Carp Red Blood Cell Membranes by Takahiko Aoki, Kenji Chimura, Hikaru Sugiura, Yasuko Mizuno

Subjects: Get full text

Study of the Effect of Cell Prestress on the Cell Membrane Penetration Behavior by Atomic Force Microscopy by Guocheng Zhang, Yufang Chang, Na Fan, Bin Yan, Xianmeng Li, Zihan Yang, Zhenyang Yu

“…It was found that the cell stiffness depends on the prestress of the cell membrane, and that the insertion rate of AFM tips into the cell membrane is proportional to the stiffness through the AFM indentation experiment. …”
Get full text

Maintaining sidedness and fluidity in cell membrane coatings supported on nano-particulate and planar surfaces by Sidi Liu, Yuanfeng Li, Linqi Shi, Jian Liu, Yijin Ren, Jon D. Laman, Henny C. van der Mei, Henk J. Busscher

“…Supported cell membrane coatings meet many requirements set to bioactive nanocarriers and materials, provided sidedness and fluidity of the natural membrane are maintained upon coating. …”
Get full text