Screening Papaveraceae as Novel Antibiofilm Natural-Based Agents by Sylwia Zielińska, Magdalena Dziągwa-Becker, Adam Junka, Ewelina Piątczak, Anna Jezierska-Domaradzka, Malwina Brożyna, Justyna Paleczny, Aleksandra Sobiecka, Wojciech Słupski, Eleonora Mess, Mariusz Kucharski, Serhat Sezai Çiçek, Christian Zidorn, Adam Matkowski

“…The impact of the extracts on cellular metabolic activity and biofilm biomass production was evaluated. …”
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Pan-Cancer analysis shows that ACO2 is a potential prognostic and immunotherapeutic biomarker for multiple cancer types including hepatocellular carcinoma by Zhen Wang, Wanqun Zheng, Zhen Chen, Shilun Wu, Haoxiao Chang, Ming Cai, Ming Cai, Heping Cai

“…Aconitase 2 (ACO2) is a component of the tricarboxylic acid cycle and represents a key cellular metabolic hub that promotes de novo fatty acid biosynthesis. …”
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A Novel Marine Pathogen Isolated from Wild Cunners (<i>Tautogolabrus adspersus</i>): Comparative Genomics and Transcriptome Profiling of <i>Pseudomonas</i> sp. Strain J380 by Navaneethaiyer Umasuthan, Katherinne Valderrama, Ignacio Vasquez, Cristopher Segovia, Ahmed Hossain, Trung Cao, Hajarooba Gnanagobal, Jennifer Monk, Danny Boyce, Javier Santander

“…Transcriptome profiling under iron-limited vs. iron-enriched conditions identified 1159 differentially expressed genes (DEGs). Cellular metabolic processes, such as ribosomal and energy production, and protein synthesis, were impeded by iron limitation. …”
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Identification and characterization of a novel molecular classification incorporating oxidative stress and metabolism-related genes for stomach adenocarcinoma in the framework of p... by Ying Dong, Ying Dong, Ying Dong, Qihang Yuan, Jie Ren, Hanshuo Li, Hui Guo, Hewen Guan, Xueyan Jiang, Bing Qi, Rongkuan Li

“…As a direct and indirect result of oncogenic mutations, cancer depends on cellular metabolic reprogramming. However, their roles in STAD remain unclear.Method743 STAD samples from GEO and TCGA platforms were selected. …”
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OTUD3 suppresses the mTORC1 signaling by deubiquitinating KPTN by Jiatao Li, Dan Yang, Yan Lin, Wei Xu, Shi-min Zhao, Chenji Wang

“…Ultimately, OTUD3 affects cellular metabolic pool products by downregulating the mTORC1 pathway, significantly inhibiting tumor cell growth and proliferation.Discussion: Our experiments shed light on an alternative perspective regarding the intrinsic functions of OTUD3 in inhibiting tumor development. …”
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RNA-Seq Comprehensive Analysis Reveals the Long Noncoding RNA Expression Profile and Coexpressed mRNA in Adult Degenerative Scoliosis by Xin Shi, Xin Shi, Panpan Li, Panpan Li, Xiang Wu, Zhihua Wang, Gang Zhao, Jun Shu

“…GO gene function prediction revealed that lncRNA-targeted genes might play a vital role in ADS via participation in multiple biological processes such as the AMPK signaling pathway, lysosomes, and ubiquitin-mediated proteolysis, as well as cellular metabolic processes. Moreover, the expression levels of three selected lncRNAs and mRNAs were validated by qRT-PCR, respectively, demonstrating that the relative expression levels were consistent with the RNA-seq data. …”
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Comprehensive analysis of serum exosome-derived lncRNAs and mRNAs from patients with rheumatoid arthritis by Li Xue, Biao Wang, Xueyi Li, Jianhong Zhu, Wei Wang, Fang Huang, Xiaofei Wang, Yaofeng Jin, Chaoliang Xiong, Li Tao, Ke Xu, Jing Wang, Ying Guo, Jing Xu, Xin Yang, Na Wang, Ning Gao, Yan Wang, Ke Li, Ming Li, Yan Geng

“…The functions of both DE-lncRNAs and DE-mRNAs in RA are associated with the immune response and cellular metabolic processes. The RT-PCR results show that NONHSAT193357.1, CCL5, and MPIG6B were downregulated in patients with RA. …”
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Impact of Porcine Arterivirus, Influenza B, and Their Coinfection on Antiviral Response in the Porcine Lung by Damarius S. Fleming, Laura C. Miller, Yun Tian, Yonghai Li, Wenjun Ma, Yongming Sang

“…The antiviral state leads to host protection through expression of hundreds of IFN-stimulated genes that restrict viral infection through multiple mechanisms, for example, directly in viral genome degradation and indirectly through cellular metabolic inhibition. Young pigs were split into four treatment groups: control, porcine reproductive and respiratory syndrome virus (PRRSV, also known as porcine arterivirus) infected, influenza B virus (IBV) infected, and IBV/PRRSV coinfection. …”
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<I>In vivo</I> vascular mapping of the human hippocampus using MICRO imaging by Sagar Buch, Yulin Ge, E. Mark E. Mark Haacke

“… BACKGROUND: There is an urgent need for better detection and understanding of vascular abnormalities at the micro-level, where critical vascular nourishment and cellular metabolic changes occur. This is especially the case for structures such as the midbrain and hippocampus, where both the feeding and draining vessels are quite small. …”
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The effect of primary blast shock wave on skeletal muscle by Staruch, RMT

“…Skeletal muscle hydrogels showed different responses to explosive loading: the 30 g charge resulted in a significant drop in cellular metabolic activity at 2 hours which failed to return to baseline by day 7. …”

Two Sides to Every Question: Attempts to Activate Chicken Innate Immunity in 2D and 3D Hepatic Cell Cultures by Csilla Sebők, Patrik Tráj, Júlia Vörösházi, Máté Mackei, Márton Papp, Péter Gálfi, Zsuzsanna Neogrády, Gábor Mátis

“…The cultures were challenged by the bacterial endotoxins lipopolysaccharide (LPS) from <i>Escherichia coli</i>, lipoteichoic acid (LTA) from <i>Staphylococcus aureus</i> and by enterotoxin (ETxB) from <i>Escherichia coli</i>, <i>Salmonella</i> Typhimurium derived flagellin, phorbol myristate acetate (PMA) as a model proinflammatory agent and polyinosinic polycytidylic acid (poly I:C) for mimicking viral RNA exposure. Cellular metabolic activity was assessed with the CCK-8 test, membrane damage was monitored with the lactate dehydrogenase (LDH) leakage assay and interleukin-6 and -8 (Il-6 and -8) concentrations were measured in cell culture medium with a chicken specific ELISA. …”
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Lipidome remodeling activities of DPA-EA in palmitic acid-stimulated HepG2 cells and the in vivo anti-obesity effect of the DPA-EA and DHA-EA mixture prepared from algae oil by Hua Fang, Yin Cao, Jianyu Zhang, Xiumei Wang, Mengyu Li, Mengyu Li, Zhuan Hong, Zhen Wu, Meijuan Fang

“…Background: The nuclear receptor Nur77 has been demonstrated to play a vital role in the inflammatory response and cellular metabolisms, and its ligands exhibit efficacy in the treatment of inflammation-related diseases (e.g., improving mouse acute lung injury (ALI) and obesity. …”
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One-Step Phytofabrication Method of Silver and Gold Nanoparticles Using <i>Haloxylon salicornicum</i> for Anticancer, Antimicrobial, and Antioxidant Activities by Reham Samir Hamida, Mohamed Abdelaal Ali, Haifa Essa Alfassam, Maha Abdullah Momenah, Mariam Abdulaziz Alkhateeb, Mashael Mohammed Bin-Meferij

“…These findings suggested that the antiproliferative activity of H@Ag-NPs is cell-response-dependent and may be influenced by a variety of factors, including the cellular metabolic state, which influences cellular charge and interactions with charged NPs. …”
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Precision nutrition to reset virus-induced human metabolic reprogramming and dysregulation (HMRD) in long-COVID by A. Satyanarayan Naidu, Chin-Kun Wang, Pingfan Rao, Fabrizio Mancini, Roger A. Clemens, Aman Wirakartakusumah, Hui-Fang Chiu, Chi-Hua Yen, Sebastiano Porretta, Issac Mathai, Sreus A. G. Naidu

“…Abstract SARS‐CoV‐2, the etiological agent of COVID-19, is devoid of any metabolic capacity; therefore, it is critical for the viral pathogen to hijack host cellular metabolic machinery for its replication and propagation. …”
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A novel DNA damage quantification platform enables high throughput screening for genes that impact DNA double strand breaks by Tay, Ian Jun Jie.

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tRNA‐derived small RNA, 5'tiRNA‐Gly‐CCC, promotes skeletal muscle regeneration through the inflammatory response by Linyuan Shen, Tianci Liao, Qiuyang Chen, Yuhang Lei, Linghui Wang, Hao Gu, Yanhao Qiu, Ting Zheng, Yiting Yang, Chenggang Wei, Lei Chen, Ye Zhao, Lili Niu, Shunhua Zhang, Yan Zhu, Mingzhou Li, Jinyong Wang, Xuewei Li, Mailin Gan, Li Zhu

“…Abstract Background Increasing evidence shows that tRNA‐derived small RNAs (tsRNAs) are not only by‐products of transfer RNAs, but they participate in numerous cellular metabolic processes. However, the role of tsRNAs in skeletal muscle regeneration remains unknown. …”
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