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201
Dynamics and functions of lipid droplets
Published 2018“…Thus, lipid droplets facilitate the coordination and communication between different organelles and act as vital hubs of cellular metabolism.…”
Journal article -
202
HIF-1α Modulates Core Metabolism and Virus Replication in Primary Airway Epithelial Cells Infected with Respiratory Syncytial Virus
Published 2020-09-01“…Our study contributes to the understanding of RSV-mediated changes to cellular metabolism and supports further investigation into anti-HIF-1α therapeutics for RSV infections.…”
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203
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204
NUAK Kinases: Brain–Ovary Axis
Published 2021-10-01“…Liver kinase B (LKB1) and adenosine monophosphate (AMP)-activated protein kinase (AMPK) are two major kinases that regulate cellular metabolism by acting as adenosine triphosphate (ATP) sensors. …”
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205
Targeting of chimeric antigen receptor T cell metabolism to improve therapeutic outcomes
Published 2023-03-01“…Distinct T cell phenotypes that are linked to cellular metabolism profiles are associated with improved anti-tumor responses. …”
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206
Spatial–temporal regulation of fatty alcohol biosynthesis in yeast
Published 2022-12-01“…Dynamically coupling the biosynthetic pathways with the cellular metabolism at spatial–temporal manner should be helpful for improving the production with alleviating the cellular stresses. …”
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207
Multiomic investigation on the relationship between metabolism and gene expression
Published 2019“…<p>Cellular metabolism and gene expression are proposed to be highly integrated but a detailed mechanistic understanding of this relationship is lacking. …”
Thesis -
208
Electronic cigarette vapor disrupts key metabolic pathways in human lung epithelial cells
Published 2024-01-01“…Concurrently, the integrity of cellular metabolism is essential for cellular homeostasis and mitigation of toxic insults. …”
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209
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210
Mitochondrial Respiratory Chain Supercomplexes: From Structure to Function
Published 2022-11-01“…Mitochondrial oxidative phospho rylation, the center of cellular metabolism, is pivotal for the energy production in eukaryotes. …”
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211
Physiology of antibiotics lethality in Mycobacteria
Published 2016“…Our results suggest that the presence of the death signature is common for at least two different classes of bactericidal antibiotics, and that there is downstream involvement of cellular metabolism processes such as respiration in antibiotics bactericidal mechanism.…”
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Final Year Project (FYP) -
212
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213
Microenvironmental regulation of cancer cell metabolism: implications for experimental design and translational studies
Published 2019“…Cancers have an altered metabolism, and there is interest in understanding precisely how oncogenic transformation alters cellular metabolism and how these metabolic alterations can translate into therapeutic opportunities. …”
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214
Modelling of the physiological response of the brain to ischaemic stroke.
Published 2013“…Recently, models of cellular metabolism after stroke and blood-brain barrier transport at tissue level have been introduced. …”
Journal article -
215
Regulation of lipid droplets by metabolically controlled Ldo isoforms
Published 2017“…Moreover, we identify ER-LD contacts as regulatory targets coupling energy storage to cellular metabolism.…”
Journal article -
216
AMPK: Regulation of Metabolic Dynamics in the Context of Autophagy
Published 2018-11-01“…In this review, we will discuss the importance of AMPK activity for diverse aspects of cellular metabolism, and how AMPK modulates autophagic degradation and adapts it to cellular energetic status. …”
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217
The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury.
Published 2012“…The principle of normothermic machine perfusion preservation is the maintenance of cellular metabolism in a physiological environment throughout the preservation period. …”
Journal article -
218
Metabolic Engineering and Adaptive Evolution for Efficient Production of l-Lactic Acid in Saccharomyces cerevisiae
Published 2022-12-01“…These findings provide new insight into improving the intrinsic efficiency of cellular metabolism and will help to construct superior industrial yeast strains for high-level production of other organic acids.…”
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219
Potential Therapeutic Functions of PU-91 and Quercetin in Personalized Cybrids Derived from Patients with Age-Related Macular Degeneration, Keratoconus, and Glaucoma
Published 2023-06-01“…PU-91(P) (i) improves cellular metabolism in AMD cybrids, (ii) decreases ROS production in AMD cybrids, and (iii) downregulates the expression of <i>LMNB1</i> in AMD cybrids. …”
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220
Heterogeneity of the cancer cell line metabolic landscape
Published 2022-11-01“…Abstract The unravelling of the complexity of cellular metabolism is in its infancy. Cancer‐associated genetic alterations may result in changes to cellular metabolism that aid in understanding phenotypic changes, reveal detectable metabolic signatures, or elucidate vulnerabilities to particular drugs. …”
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Article