Mechanisms and Functions of Pexophagy in Mammalian Cells by Jing Li, Wei Wang

“…Peroxisomes play essential roles in diverse cellular metabolism functions, and their dynamic homeostasis is maintained through the coordination of peroxisome biogenesis and turnover. …”
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Human Cytomegalovirus Egress: Overcoming Barriers and Co-Opting Cellular Functions by Veronica Sanchez, William Britt

“…Similarly, significant changes occur in cellular metabolism, protein trafficking, and cellular homeostatic functions. …”
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Multiple Roles of Sirtuin 6 in Adipose Tissue Inflammation by Eun Ju Bae, Byung-Hyun Park

“…Although sirtuin 6 (Sirt6) is known to control genomic stabilization, aging, and cellular metabolism, it is now understood to also play a pivotal role in the regulation of AT inflammation. …”
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Recent Advances in the Synthesis and Biomedical Applications of Heterocyclic NO-Donors by Leonid L. Fershtat, Egor S. Zhilin

“…Nitric oxide (NO) is a key signaling molecule that acts in various physiological processes such as cellular metabolism, vasodilation and transmission of nerve impulses. …”
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Antioxidant Production in <i>Dunaliella</i> by Uttam Kumer Roy, Birthe Vejby Nielsen, John James Milledge

“…This review provides a detailed overview of enzymatic and non-enzymatic antioxidants in the cellular metabolism of the commercially important microalgae <i>Dunaliella,</i> industrial applications of antioxidant enzymes, strategies to enhanced antioxidant accumulation in cells, and the opportunities and limitations of current technologies for antioxidant enzymes production from microalgae biomass as an alternative to common microbial sources.…”
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State of Shock: Contemporary Vasopressor and Inotrope Use in Cardiogenic Shock by Jason E. Bloom, William Chan, David M. Kaye, Dion Stub

“…In addition to treating the pathologic process causing impaired cardiac function, prompt hemodynamic support is essential to reduce the risk of developing multiorgan dysfunction and to preserve cellular metabolism. Pharmacologic therapy with the use of vasopressors and inotropes is a key component of this treatment strategy, improving perfusion by increasing cardiac output, altering systemic vascular resistance, or both, while allowing time and hemodynamic stability to treat the underlying disease process implicated in the development of cardiogenic shock. …”
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Phasor identifier: A cloud-based analysis of phasor-FLIM data on Python notebooks by Mario Bernardi, Francesco Cardarelli

“…This approach simplifies FLIM data handling and opens doors for diverse applications, from studying cellular metabolism to investigating drug encapsulation, benefiting researchers across multiple domains. …”
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Cell metabolism pathways involved in the pathophysiological changes of diabetic peripheral neuropathy by Yaowei Lv, Xiangyun Yao, Xiao Li, Yuanming Ouyang, Cunyi Fan, Yun Qian

“…This review summarizes the pathophysiological mechanism of diabetic peripheral neuropathy from the perspective of cellular metabolism and the specific interventions for different metabolic pathways to develop effective treatment methods. …”
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Advances in Autophagy Regulatory Mechanisms by Laura E. Gallagher, Leon E. Williamson, Edmond Y. W. Chan

“…Based on this simple scheme, autophagy modulates cellular metabolism and cytoplasmic quality control to influence an unexpectedly wide range of normal mammalian physiology and pathophysiology. …”
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Platelets from Asthmatic Individuals Show Less Reliance on Glycolysis. by Weiling Xu, Nayra Cardenes, Catherine Corey, Serpil C Erzurum, Sruti Shiva

“…While immune function plays a major role in the pathogenesis of the disease, accumulating evidence suggests that altered cellular metabolism is a key determinant in the predisposition and disease progression of asthma. …”
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Relevance of Sugar Transport across the Cell Membrane by Roxana Carbó, Emma Rodríguez

“…Sugar transport through the plasma membrane is one of the most critical events in the cellular transport of nutrients; for example, glucose has a central role in cellular metabolism and homeostasis. The way sugars enter the cell involves complex systems. …”
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Macrophage metabolism, phenotype, function, and therapy in hepatocellular carcinoma (HCC) by Jingquan Huang, Qiulin Wu, David A. Geller, Yihe Yan

“…This comprehensive review elucidates the intricate interplay between cellular metabolism and macrophage phenotype/polarization, while also providing an overview of the associated signaling molecules and potential therapeutic strategies for HCC.…”
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Protocol to assess bioenergetics and mitochondrial fuel usage in murine autoreactive immunocytes using the Seahorse Extracellular Flux Analyzer by Colleen L. Mayberry, John J. Wilson, Britney Sison, Chih-Hao Chang

“…Here, we present a protocol for examining the bioenergetics and mitochondrial fuel utilization of primary murine autoreactive immunocytes using cellular metabolism-modulating drugs. We describe steps for plate calibration, isolation of primary immunocytes, and Seahorse assay plate preparation. …”
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Recent Development of Lysosome-Targeted Organic Fluorescent Probes for Reactive Oxygen Species by Van-Nghia Nguyen, Haidong Li

“…Lysosome plays key roles in cellular metabolism and has been known as the stomach of cells. …”
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Sirtuin 3 (SIRT3) Pathways in Age-Related Cardiovascular and Neurodegenerative Diseases by Ciprian N. Silaghi, Marius Farcaș, Alexandra M. Crăciun

“…SIRT3 activity declines as a result of aging-induced changes in cellular metabolism, leading to increased susceptibility to endothelial dysfunction, hypertension, heart failure and neurodegenerative diseases. …”
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Brain Innate Immune Response in Diet-Induced Obesity as a Paradigm for Metabolic Influence on Inflammatory Signaling by Felipe Macedo, Lucas Souza dos Santos, Isaias Glezer, Fernanda Marques da Cunha

“…Since the metabolic state influences immune responses of microglia and other myeloid cells, the understanding and characterization of the effects of cellular metabolism on the functions of these cells, and their impact on brain integrity, are crucial for the development of efficient therapeutic interventions for individuals exposed to a long-term high fat diet (HFD). …”
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Metabolic Regulation of Hematopoietic Stem Cells by Claudia Morganti, Nina Cabezas-Wallscheid, Keisuke Ito

“…Cellular metabolism is a key regulator of hematopoietic stem cell (HSC) maintenance. …”
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Therapy Follows Diagnosis: Old and New Approaches for the Treatment of Acute Porphyrias, What We Know and What We Should Know by Petro E. Petrides

“…Consequently, inborn errors of porphyrin metabolism that compromise normal synthesis, namely the family of porphyrias, undermine normal cellular metabolism given that heme has functions in catalytic centers, signal transduction and functional regulation and its synthesis is fully integrated into the center of intermediary metabolism. …”
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Mechanisms of venetoclax resistance and solutions by Jiachen Liu, Yidong Chen, Lihua Yu, Lihua Yang

“…Additionally, this paper also summarizes the current investigations of the mechanisms of venetoclax resistance in terms of altered cellular metabolism, changes in the mitochondrial structure, altered or modified BCL-2 binding domains, and some other aspects; this article also reviews relevant strategies to address these resistance mechanisms.…”
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The Role of Insulin-like Growth Factor-1 (IGF-1) in the Control of Neuroendocrine Regulation of Growth by Sarmed Al-Samerria, Sally Radovick

“…In mammals, the neuroendocrine system, which includes the communication between the hypothalamus and the pituitary, plays a major role in controlling body growth and cellular metabolism. GH produced from the pituitary somatotroph is considered the master regulator of somatic development and involved, directly and indirectly, in carbohydrate and lipid metabolism via complex, yet well-defined, signaling pathways. …”
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