COVID-19 and Coronary Heart Disease by Adiba Naz, Muntasir Billah

“…Depletion of oxygen switches the aerobic cellular metabolism to anaerobic metabolism and impairs the oxidative phosphorylation pathway eventually leading to cardiomyocyte death. …”
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Integral Hematological Indices and Immunological Parameters in Acute Poisoning in Children by L. A. Kovalenko, G. N. Sukhodolova

“…The absorbing capacity of neutrophils remained unchanged and oxygen-dependent cellular metabolism was enhanced. Conclusion. Immunological findings and integral hematological indices point to immune system functional changes forming in children via a systemic response to acute chemical poisoning. …”
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Mathematical model of oxygen, nutrient, and drug transport in tuberculosis granulomas. by Meenal Datta, McCarthy Kennedy, Saeed Siri, Laura E Via, James W Baish, Lei Xu, Véronique Dartois, Clifton E Barry, Rakesh K Jain

“…Building on our initial model of avascular oxygen diffusion, here we explore additional aspects of oxygen transport, including the roles of granuloma vasculature, transcapillary transport, plasma dilution, and interstitial convection, followed by cellular metabolism. Approximate analytical solutions are provided for oxygen and glucose concentration, interstitial fluid velocity, interstitial fluid pressure, and the thickness of the convective zone. …”
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The effect of caloric restriction on genetical pathways by Mustafa Fevzi Karagöz, A. Gülçin Sağdıçoğlu Celep

“…As a consequence, the effects of caloric restriction on cellular metabolism are regulated through the genetic pathways.…”
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Low-Digit and High-Digit Polymers in the Origin of Life by Peter Strazewski

“…Extant life uses two kinds of linear biopolymers that mutually control their own production, as well as the cellular metabolism and the production and homeostatic maintenance of other biopolymers. …”
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Iron at the center of ferritin, metal/oxygen homeostasis and novel dietary strategies by X LIU, K HINTZE, B LONNERDAL, EC THEIL

“…Ferritin gene regulation is a model for integrating DNA/mRNA controls, while ferritin protein function is central to molecular nutrition cellular metabolism at the crossroads of iron and oxygen in biology…”
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The Role of Trace Elements in Cardiovascular Diseases by Christian Wechselberger, Barbara Messner, David Bernhard

“…Essential trace elements play an important role in human physiology and are associated with various functions regulating cellular metabolism. Non-essential trace elements, on the other hand, often have well-documented toxicities that are dangerous for the initiation and development of diseases due to their widespread occurrence in the environment and their accumulation in living organisms. …”
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Architecture of the human mTORC2 core complex by Edward Stuttfeld, Christopher HS Aylett, Stefan Imseng, Daniel Boehringer, Alain Scaiola, Evelyn Sauer, Michael N Hall, Timm Maier, Nenad Ban

“…The mammalian target of rapamycin (mTOR) is a key protein kinase controlling cellular metabolism and growth. It is part of the two structurally and functionally distinct multiprotein complexes mTORC1 and mTORC2. …”
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Metabolic Flexibility Is a Determinant of Breast Cancer Heterogeneity and Progression by Marina Fukano, Morag Park, Geneviève Deblois

“…Breast cancer progression is characterized by changes in cellular metabolism that contribute to enhanced tumour growth and adaptation to microenvironmental stresses. …”
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The Interplay between Autophagy and Redox Signaling in Cardiovascular Diseases by Barbora Boťanská, Ima Dovinová, Miroslav Barančík

“…Reactive oxygen and nitrogen species produced at low levels under normal cellular metabolism act as important signal molecules. However, at increased production, they cause damage associated with oxidative stress, which can lead to the development of many diseases, such as cardiovascular, metabolic, neurodegenerative, diabetes, and cancer. …”
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Rifaximin-mediated changes to the epithelial cell proteome: 2-D gel analysis. by Caroline Schrodt, Erin E McHugh, Mary Ann Gawinowicz, Herbert L Dupont, Eric L Brown

“…Many of the identified proteins are associated with cell structure and cytoskeleton, transcription and translation, and cellular metabolism. These data suggested that in addition to its antimicrobial properties, rifaximin may alter host cell physiology that provides cytoprotective effects against bacterial pathogens.…”
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Redox and Metabolic Regulation of Intestinal Barrier Function and Associated Disorders by Pei-Yun Lin, Arnold Stern, Hsin-Hsin Peng, Jiun-Han Chen, Hung-Chi Yang

“…Understanding the regulation of tight junctions by cellular metabolism and redox status in cells may lead to the identification of potential targets for therapeutic interventions. …”
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The other immuno-PET: Metabolic tracers in evaluation of immune responses to immune checkpoint inhibitor therapy for solid tumors by Jelena Levi, Hong Song

“…Small molecule metabolic tracers, largely neglected in the immuno-PET discourse, offer a way to monitor immune responses by assessing cellular metabolism known to be intricately linked with immune cell function. …”
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Interactions of HMGB Proteins with the Genome and the Impact on Disease by Calvin K. Voong, James A. Goodrich, Jennifer F. Kugel

“…Nuclear HMGB proteins have broad regulatory potential to impact numerous aspects of cellular metabolism in normal and disease states.…”
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Coordination of Multiple Cellular Processes by by Ken-ichirou Morohashi, Miki Inoue, Takashi Baba

“…Considering that active cellular processes are expected to be accompanied by active metabolism, NR5A1 may act as a key factor for processes such as cell differentiation, proliferation, and survival by coordinating these processes with cellular metabolism. A complete and definite picture of the cellular processes coordinated by NR5A1/Nr5a1 could be depicted by accumulating evidence of the potential target genes through whole genome studies.…”
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Disorders of Human Coenzyme Q10 Metabolism: An Overview by Iain Hargreaves, Robert A. Heaton, David Mantle

“…In view of the central role of CoQ10 in cellular metabolism, it is unsurprising that a CoQ10 deficiency is linked to the pathogenesis of a range of disorders. …”
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A human-mouse conserved sex bias in amygdala gene expression related to circadian clock and energy metabolism by Lin Li-Chun, Lewis David A, Sibille Etienne

“…Hence, baseline differences in amygdalar circadian regulation of cellular metabolism may contribute to sex-related differences in mood regulation and vulnerability to major depression.…”
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The Potential Role of Spermine and Its Acetylated Derivative in Human Malignancies by Ryan Tsz-Hei Tse, Christine Yim-Ping Wong, Peter Ka-Fung Chiu, Chi-Fai Ng

“…Polyamines are essential biomolecules for normal cellular metabolism in humans. The roles of polyamines in cancer development have been widely discussed in recent years. …”
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The Influence of Cellular Redox State on Mitosis by Sapp, Kiera Marie

“…This work identifies a novel mechanism by which cellular metabolism regulates cell cycle progression and has important impacts for human diseases such as cancer, as errors in cell division are directly linked to aberrant proliferation.…”
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Functional impact of high extracellular potassium ion on human T-cells by Wong, Brandon Han Siang

“…Using Jurkat T-cell line as a model, we observed that high-[K+]e reduces T-cell cytokines (IL-2 and IFN-𝛾) production and modulates both AMPK𝛼 and ACC expression and phosphorylation, which are prerequisite factors in cellular metabolism. Taken together, high-[K+]einduced impairment of T-cell functions reported in the current study has implications in T-cell anti-tumor immune responses and immunotherapies.…”
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