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581
The Role of Fe, Zn, and Cu in Pregnancy
Published 2020-08-01“…These elements participatein many processes, including cellular metabolism and antioxidant and anti-inflammatory defenses, and also influence enzyme activity, regulate gene expression, and take part in protein synthesis. …”
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582
Activated cholesterol metabolism is integral for innate macrophage responses by amplifying Myd88 signaling
Published 2022-11-01“…Recent studies have shown that cellular metabolism is tightly linked to the regulation of immune cells. …”
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583
Metabolic Stress in the Immune Function of T Cells, Macrophages and Dendritic Cells
Published 2018-06-01“…In this review, we detail how cellular metabolism controls immune function and phenotype within T cells and macrophages particularly, and the distinct molecular metabolic programming and targets instrumental to engage this regulation.…”
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584
Teasing out missing reactions in genome-scale metabolic networks through hypergraph learning
Published 2023-04-01“…Abstract GEnome-scale Metabolic models (GEMs) are powerful tools to predict cellular metabolism and physiological states in living organisms. …”
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585
Aiding Cancer’s “Sweet Tooth”: Role of Hexokinases in Metabolic Reprogramming
Published 2023-04-01“…HKs participate in various standard and altered physiological processes, including cancer, primarily through the reprogramming of cellular metabolism. Four canonical HKs have been identified with different expression patterns across tissues. …”
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586
Hyaluronan: Metabolism and Function
Published 2020-11-01“…In addition to the well-known functions exerted by extracellular hyaluronan, recent metabolomic approaches have also revealed that its synthesis can regulate cellular functions via the reprogramming of cellular metabolism. This review highlights the current advances in knowledge on the biosynthesis and catabolism of hyaluronan and describes the diverse functions associated with hyaluronan metabolism.…”
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587
Research Concerning Antimicrobial Activities of Some Essential Oils Extracted from Plants
Published 2023-09-01“…Their action mechanism is unclear, but some studies suggest that the compounds penetrate the cell, where they interfere with cellular metabolism. The purpose of this study was to evaluate the antimicrobial activity of 5 essential oils extracted from plants on Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica, Staphylococcus aureus and Bacillus cereus and to determinate how different amount of the used oils can influence the results of inhibition tests. …”
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588
Nutrigenomics of Vitamin D
Published 2019-03-01“…Vitamin D is important for both cellular metabolism and immunity, as it controls calcium homeostasis and modulates the response of the innate and adaptive immune system. …”
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589
Metabolomic Approach to Redox and Nitrosative Reactions in Cardiovascular Diseases
Published 2018-06-01“…Metabolites (<1500 Da) represent the output of cellular metabolism, accounting for expression and activity of genes, transcripts, and proteins, and offering unique insights into small molecule regulation, which may uncover new biochemical patterns. …”
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590
mTOR/α-ketoglutarate signaling: impact on brain cell homeostasis under ischemic conditions
Published 2023-05-01“…Upon exceeding a threshold of resistance to OGD, essential pathways of cellular metabolism can be disrupted, leading to damage of brain cells up to the loss of function and death. …”
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591
SALICYLIC ACID MITIGATES Pb STRESS IN NICOTINA TABACUM
Published 2017-01-01“…ROS are highly reactive substances that capable of altering normal cellular metabolism via oxidative damage to membranes, proteins, and nucleic acids. …”
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592
The Role of PPAR Alpha in the Modulation of Innate Immunity
Published 2021-09-01“…Peroxisome proliferator-activated receptor α is a potent regulator of systemic and cellular metabolism and energy homeostasis, but it also suppresses various inflammatory reactions. …”
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593
The Influence of Arginine Methylation in Immunity and Inflammation
Published 2022-05-01“…Protein arginine methylation is known to regulate fundamental cellular processes, such as transcription; pre-mRNA splicing and other RNA processing mechanisms; signal transduction, including the anti-viral response; and cellular metabolism. PRMTs are also implicated in the regulation of physiological processes, including embryonic development, myogenesis, and the immune system. …”
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594
Role of cyclooxygenase-2 in Trypanosoma cruzisurvival in the early stages of parasite host-cell interaction
Published 2015-04-01“…Our collective findings suggest that in the very early stage of the T. cruzi-host cell interaction, the parasite is able to modulate the cellular metabolism in order to survives.…”
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595
Control of Cholesterol Metabolism Using a Systems Approach
Published 2022-03-01“…Disruption of the cellular metabolism of cholesterol, accompanied by inflammation and oxidative stress, promotes the formation of atherosclerotic plaques and, consequently, is one of the leading causes of death in the Western world. …”
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596
Metabolic Basis of Circadian Dysfunction in Parkinson’s Disease
Published 2023-09-01“…In this review, we discuss the intricate relationship between circadian dysfunction in cellular metabolism and PD by summarizing the evidence from animal models and human studies. …”
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597
Mining cancer genomes for change-of-metabolic-function mutations
Published 2023-11-01“…Drawing inspiration from gain-of-function cancer mutations that functionally alter proteins and affect cellular metabolism, we developed METIS (Mutated Enzymes from Tumors I n silico Screen). …”
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598
Human Mitoribosome Biogenesis and Its Emerging Links to Disease
Published 2021-04-01“…Therefore, their function is of fundamental importance to cellular metabolism. The assembly of mitoribosomes is a complex process that progresses through numerous maturation and protein-binding events coordinated by the actions of several assembly factors. …”
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599
Metabolism-Associated Epigenetic and Immunoepigenetic Reprogramming in Liver Cancer
Published 2021-10-01“…Independently of etiology, oncogenic pathways as well as the availability of different energetic substrates critically influence cellular metabolism, and the resulting perturbations often cause aberrant epigenetic alterations, not only in cancer cells but also in the hepatic tumor microenvironment. …”
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600
Notch Signaling and Cross-Talk in Hypoxia: A Candidate Pathway for High-Altitude Adaptation
Published 2022-03-01“…We assessed transcriptional regulation of the Notch pathway, including close cross-talk with HIF signaling, and its involvement in the mediation of angiogenesis, cellular metabolism, inflammation, and oxidative stress, relating these functions to generational hypoxia adaptation.…”
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