Advances of mitophagy involved in diabetic retinopathy by Shi-Yi Li, Ke Wang, Wen-Jun Zou

“…Mitochondrial function is essential for the viability of aerobic eukaryotic cells, as mitochondria provide energy through the generation of adenosine triphosphate(ATP), regulate cellular metabolism, provide redox balancing, participate in immune signaling, and initiate apoptosis. …”
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A Whole New Comprehension about ncRNA-Encoded Peptides/Proteins in Cancers by Qinnan Chen, Hongyu Shen, Fengqi Nie, Ming Sun

“…An increasing body of evidence have revealed different functions and mechanisms of ncRNA-encoded peptides/proteins in cancers, including regulation of signal transduction (Wnt/β-catenin signaling, AKT-related signaling, MAPK signaling and other signaling), cellular metabolism (Glucose metabolism and Lipid metabolism), protein stability, transcriptional regulation, posttranscriptional regulation (regulation of RNA stability, mRNA splicing and translation initiation). …”
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The crisscross between p53 and metabolism in cancer by Mao Youxiang, Jiang Peng

“…Recently, there has been increasing evidence that p53 plays a vital role in regulating cellular metabolism as well as in metabolic adaptation to nutrient starvation. …”
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Connecting mutations of the RNA polymerase II C-terminal domain to complex phenotypic changes using combined gene expression and network analyses. by Carlyle Rogers, Zhenhua Guo, John W Stiller

“…Such results can help to direct future genetic and biochemical investigations that tie together the complex impacts of the CTD on global cellular metabolism.…”
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HYPERAMMONIUM IN PATIENTS WITH PRECIRRHOSIS STAGE: CLINICAL REALITY? by L. Yu. Ilchenko, I. G. Nikitin

“…Ammonia induces the formation of oxygen active forms, reduces the activity of endothelial NO synthase, dose-dependently decreases the cellular metabolism and proliferation of stellate cells, and promotes fibrogenesis, disturbance of intrahepatic hemodynamics and, accordingly, the formation of portal hypertension. …”
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Role of lysosome in healing neurological disorders by nano-bioengineering by Aiswarya Raj, Urmi Bandyopadhyay

“…Lysosomes primarily recognized as center for cellular ‘garbage-disposing-unit’, which has recently emerged as a crucial regulator of cellular metabolism. This organelle is a well-known vital player in the pathology including neurodegenerative disorders. …”
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Histone Acyl Code in Precision Oncology: Mechanistic Insights from Dietary and Metabolic Factors by Sultan Neja, Wan Mohaiza Dashwood, Roderick H. Dashwood, Praveen Rajendran

“…Histone post-translational modifications (PTMs), including acyl marks, act as a molecular code and play a crucial role in translating changes in cellular metabolism into enduring patterns of gene expression. …”
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A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes by Iredia D. Iyamu, Ayad A. Al-Hamashi, Rong Huang

“…Protein arginine methyltransferases (PRMTs) play important roles in transcription, splicing, DNA damage repair, RNA biology, and cellular metabolism. Thus, PRMTs have been attractive targets for various diseases. …”
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Cancer Metabolism and the Evasion of Apoptotic Cell Death by Aditi Sharma, Lawrence H. Boise, Mala Shanmugam

“…While apoptosis is in itself an energy dependent process activated by intrinsic and extrinsic signals, whether specific nutrient acquisition (elevated or suppressed) and their metabolism regulates apoptosis is less well investigated. Normal cellular metabolism is regulated by lineage specific intrinsic features and microenvironment driven extrinsic features. …”
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Diverse Roles of SIRT1 in Cancer Biology and Lipid Metabolism by Glenn E. Simmons, Wendy M. Pruitt, Kevin Pruitt

“…This review helps to show the various connections between SIRT1 and major pathways in cellular metabolism and the consequence of SIRT1 deregulation on carcinogenesis and lipid metabolism.…”
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NADH-based kinetic model for acetone-butanol-ethanol production by Clostridium by Juan Carlos Quintero-Díaz, Diego F. Mendoza, Claudio Avignone-Rossa

“…The model includes the effect of the co-substrate NADH as a modulating factor of cellular metabolism. The simulations obtained with the model showed an adequate fit to the experimental data reported by several authors, matching or improving the results observed with previous models. …”
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The Intricate Interplay between Cell Cycle Regulators and Autophagy in Cancer by Dorian V. Ziegler, Katharina Huber, Lluis Fajas

“…In the past decade, cell cycle regulators have extended their canonical role in cell cycle progression to the regulation of various cellular processes, including cellular metabolism. The regulation of metabolism is intimately connected with the function of autophagy, a catabolic process that promotes the efficient recycling of endogenous components from both extrinsic stress, e.g., nutrient deprivation, and intrinsic sub-lethal damage. …”
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Fibroblasts as Modulators of Local and Systemic Cancer Metabolism by Hannah Sanford-Crane, Jaime Abrego, Mara H. Sherman

“…Emerging evidence suggests that fibroblastic cells in the microenvironments of solid tumors also critically modulate cellular metabolism in the neoplastic compartment through mechanisms including paracrine transfer of metabolites or non-cell-autonomous regulation of metabolic signaling pathways. …”
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Oncolytic Virotherapy: The Cancer Cell Side by Marcelo Ehrlich, Eran Bacharach

“…Cell autonomous immunity genes mediate the multiple stages of anti-viral defenses, including recognition of invading pathogens, inhibition of viral replication, reprogramming of cellular metabolism, programmed-cell-death, paracrine induction of antiviral state, and activation of immunostimulatory inflammation. …”
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A New Integrated Lab-on-a-Chip System for Fast Dynamic Study of Mammalian Cells under Physiological Conditions in Bioreactor by An-Ping Zeng, Ralf Pörtner, Jörg Müller, Grischa Fuge, Janina Bahnemann, Oscar Platas Barradas, Negar Rajabi

“…For the quantitative analysis of cellular metabolism and its dynamics it is essential to achieve rapid sampling, fast quenching of metabolism and the removal of extracellular metabolites. …”
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Maximization of information transmission influences selection of native phosphorelay architectures by Rui Alves, Baldiri Salvadó, Ron Milo, Ester Vilaprinyo, Albert Sorribas

“…Phosphorelays are signal transduction circuits that sense environmental changes and adjust cellular metabolism. Five different circuit architectures account for 99% of all phosphorelay operons annotated in over 9,000 fully sequenced genomes. …”
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How the Disruption of Mitochondrial Redox Signalling Contributes to Ageing by Beatriz Castejon-Vega, Mario D. Cordero, Alberto Sanz

“…In the past, mitochondrial reactive oxygen species (mtROS) were considered a byproduct of cellular metabolism. Due to the capacity of mtROS to cause oxidative damage, they were proposed as the main drivers of ageing and age-related diseases. …”
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Itaconate-producing neutrophils regulate local and systemic inflammation following trauma by Janna L. Crossley, Sonya Ostashevskaya-Gohstand, Stefano Comazzetto, Jessica S. Hook, Lei Guo, Neda Vishlaghi, Conan Juan, Lin Xu, Alexander R. Horswill, Gerta Hoxhaj, Jessica G. Moreland, Robert J. Tower, Benjamin Levi

“…Due to the evolving role of cellular metabolism in regulating cell fate and function, tendon injuries that undergo normal and aberrant repair were evaluated by metabolic profiling to determine its impact on healing outcomes. …”
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DNA damage protection: an excellent application of bioactive compounds by Pinderpal Kaur, Sukhvinder Singh Purewal, Kawaljit Singh Sandhu, Maninder Kaur

“…Abstract Discovery of deoxyribonucleic acid (DNA) solved out the mystery of cellular functioning and abnormality in cellular metabolism. Understanding the coding of DNA resulted in enormous medical growth and helps the researchers in finding the genes which trigger major chronic diseases in humans. …”
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Lipid Droplets: A Key Cellular Organelle Associated with Cancer Cell Survival under Normoxia and Hypoxia by Shiro Koizume, Yohei Miyagi

“…Cancer cells have multiple molecular mechanisms to adapt to such stress conditions by reprogramming the cellular metabolism. Hypoxia-inducible factors are major transcription factors induced in cancer cells in response to hypoxia that contribute to the metabolic changes. …”
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