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681
Vitamin B12 in Cats: Nutrition, Metabolism, and Disease
Published 2023-04-01“…Cobalamin is a water-soluble molecule that has an important role in cellular metabolism, especially in DNA synthesis, methylation, and mitochondrial metabolism. …”
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682
Advances in Understanding the Links between Metabolism and Autophagy in Acute Myeloid Leukemia: From Biology to Therapeutic Targeting
Published 2023-06-01“…Autophagy is a highly conserved cellular degradation process that regulates cellular metabolism and homeostasis under normal and pathophysiological conditions. …”
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683
Wheat Production under Drought Stress Conditions: Physiological and Biochemical Responses and Mitigation Options
Published 2023-06-01“…Drought triggers a wide variety of plant responses, ranging from cellular metabolism to changes in growth rates and crop yields. …”
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684
Cellular Red-Ox system in health and disease: The latest update
Published 2023-06-01“…Cells are continually exposed to reactive oxygen species (ROS) generated during cellular metabolism. Apoptosis, necrosis, and autophagy are biological processes involving a feedback cycle that causes ROS molecules to induce oxidative stress. …”
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685
Continuous Protein Supplementation Reduces Acute Exercise-Induced Stress Markers in Athletes Performing Marathon
Published 2021-08-01“…In conclusion, supplementary protein intake may influence exercise-induced muscle stress reactions by changing cellular metabolism and inflammatory pathways.…”
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686
Oxygen dependence of nitric oxide-mediated signaling
Published 2013-01-01“…Both the enzymatic synthesis and the predominant forms of cellular metabolism of ·NO are oxygen-dependent. For these reasons, changes in local oxygen concentrations can have a profound influence on steady-state ·NO concentrations. …”
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687
Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5
Published 2018-10-01“…Abstract Background Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. …”
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688
Metabolism of Polyamines and Kidney Disease: A Promising Therapeutic Target
Published 2023-08-01“…Summary: The alteration in cellular metabolism has emerged as an important common pathological mechanism in different kidney diseases. …”
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689
GEM-Based Metabolic Profiling for Human Bone Osteosarcoma under Different Glucose and Glutamine Availability
Published 2021-02-01“…In this context, understanding how these two aspects interact and how diet influences cellular metabolism is important for developing personalized treatment. …”
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690
Bicyclomycin generates ROS and blocks cell division in Escherichia coli.
Published 2024-01-01“…Evidence attributes part of toxicity of many antibiotics to their ability to generate ROS by interfering with cellular metabolism, but some studies dismiss the role of ROS. …”
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691
Metabolic Phenotyping in Prostate Cancer Using Multi-Omics Approaches
Published 2022-01-01“…It is well known that PCa cells rewire their cellular metabolism to meet the higher demands required for survival, proliferation, and invasion. …”
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692
Mitochondrial Metabolism: A New Dimension of Personalized Oncology
Published 2023-08-01“…The primary organelles for cellular metabolism and energy synthesis are mitochondria. …”
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693
Lipocalin 2 Deficiency Alters Prostaglandin Biosynthesis and mTOR Signaling Regulation of Thermogenesis and Lipid Metabolism in Adipocytes
Published 2022-05-01“…However, the physiological mechanism through which Lcn2 regulates cellular metabolism and thermogenesis in adipocytes remains unknown. …”
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694
Induced pluripotent stem cells: ex vivo models for human diseases due to mitochondrial DNA mutations
Published 2023-09-01“…Abstract Mitochondria are essential organelles for cellular metabolism and physiology in eukaryotic cells. …”
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695
Bacteria exposed to antiviral drugs develop antibiotic cross-resistance and unique resistance profiles
Published 2023-08-01“…Whole genome sequencing of antiviral-resistant E. coli isolates revealed numerous unique single base pair mutations, as well as multi-base pair insertions and deletions, in genes with known and suspected roles in antimicrobial resistance including those coding for multidrug efflux pumps, carbohydrate transport, and cellular metabolism. The observed phenotypic changes coupled with genotypic results indicate that bacteria exposed to antiviral drugs with antibacterial properties in vitro can develop multiple resistance mutations that confer cross-resistance to antibiotics. …”
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696
mTORC1 Deficiency Prevents the Development of MC903-Induced Atopic Dermatitis through the Downregulation of Type 2 Inflammation
Published 2023-03-01“…Recently, mTORC, a central regulator of cellular metabolism, has been reported to play a critical role in immune responses, and manipulation of mTORC pathways has emerged as an effective immunomodulatory drug. …”
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697
Short-chain L-3-hydroxyacyl-CoA dehydrogenase: A novel vital oncogene or tumor suppressor gene in cancers
Published 2022-10-01“…The reprogramming of cellular metabolism is frequently linked to tumorigenesis. …”
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698
H2S-Induced Sulfhydration: Biological Function and Detection Methodology
Published 2017-09-01“…A variety of key proteins of different cellular pathways in mammals have been reported to be sulfhydrated by hydrogen sulfide to participate and regulate the processes of cell survival/death, cell differentiation, cell proliferation/hypertrophy, cellular metabolism, mitochondrial bioenergetics/biogenesis, endoplasmic reticulum stress, vasorelaxtion, inflammation, oxidative stress, etc. …”
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699
Coenzyme a Biochemistry: From Neurodevelopment to Neurodegeneration
Published 2021-08-01“…In this review, we will summarize the most relevant aspects of CoA cellular metabolism, their role in the pathogenesis of selected neurodevelopmental and neurodegenerative disorders, and recent advancements in the search for therapeutic approaches for such diseases.…”
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700
Mitochondrial DNA in the regulation of innate immune responses
Published 2015-10-01“…Therefore, in addition to its well-appreciated roles in cellular metabolism and energy production, mtDNA appears to function as a key member in the innate immune system. …”
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