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781
Foci-forming regions of pyruvate kinase and enolase at the molecular surface incorporate proteins into yeast cytoplasmic metabolic enzymes transiently assembling (META) bodies.
Published 2023-01-01“…Spatial reorganization of metabolic enzymes to form the "metabolic enzymes transiently assembling (META) body" is increasingly recognized as a mechanism contributing to regulation of cellular metabolism in response to environmental changes. …”
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782
Molecular Mechanisms of Microbial Extracellular Electron Transfer: The Importance of Multiheme Cytochromes
Published 2022-06-01“…In numerous electroactive organisms, these proteins form a conductive pathway that allows electrons produced from cellular metabolism to be transferred across the cell surface for the reduction of an electrode, or vice-versa. …”
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783
Impact of EcSOD Perturbations in Cancer Progression
Published 2021-07-01“…Reactive oxygen species (ROS) are a normal byproduct of cellular metabolism and are required components in cell signaling and immune responses. …”
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784
Intraspecific variation in oxidative stress tolerance in a model cnidarian: Differences in peroxide sensitivity between and within populations of Nematostella vectensis.
Published 2018-01-01“…N. vectensis populations are continually exposed to reactive oxygen species (ROS) generated during cellular metabolism and by other environmental factors. …”
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785
Imaging Techniques for Detecting Prokaryotic Viruses in Environmental Samples
Published 2021-10-01“…Prokaryotic viruses—bacteriophages and archaeal viruses—influence global biogeochemical cycles by shaping microbial communities through predation, through the effect of horizontal gene transfer on the host genome evolution, and through manipulating the host cellular metabolism. Imaging techniques have played an important role in understanding the biology and lifestyle of prokaryotic viruses. …”
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786
Role of Impaired Mitochondrial Dynamics Processes in the Pathogenesis of Alzheimer’s Disease
Published 2022-06-01“…Mitochondria are signaling organelles with a variety of functions ranging from energy production to the regulation of cellular metabolism, energy homeostasis, and response to stress. …”
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787
Occludin: a gatekeeper of brain Infection by HIV-1
Published 2023-10-01“…Recent evidence indicated occludin as a redox-sensitive, multifunctional protein that can act as both an NADH oxidase and influence cellular metabolism through AMPK kinase. One of the newly identified functions of occludin is its involvement in regulating HIV-1 infection. …”
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788
Antioxidant Activity of Total Phenols and Flavonoids Extracted from Echinops polyceras Roots Grown in Syria
Published 2022-06-01“…Free radicals are products of normal cellular metabolism, they are unstable, short-lived, and highly reactive and the excessive production of them may cause numerous degenerative diseases like cancer. …”
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789
HIV-1 replication and latency are balanced by mTOR-driven cell metabolism
Published 2022-11-01“…Thus, understanding and exploring new connections between cellular metabolism and HIV-1 pathogenesis may yield new insights into the latent viral reservoirs and fuel novel treatments and cure strategies.…”
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790
Architect: A tool for aiding the reconstruction of high-quality metabolic models through improved enzyme annotation.
Published 2022-09-01“…Constraint-based modeling is a powerful framework for studying cellular metabolism, with applications ranging from predicting growth rates and optimizing production of high value metabolites to identifying enzymes in pathogens that may be targeted for therapeutic interventions. …”
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791
The Role of Non-Coding RNAs in the Regulation of the Proto-Oncogene MYC in Different Types of Cancer
Published 2021-07-01“…Overexpressed MYC has been shown to stimulate the main processes of oncogenesis: uncontrolled growth, unlimited cell divisions, avoidance of apoptosis and immune response, changes in cellular metabolism, genomic instability, metastasis, and angiogenesis. …”
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792
The role of N-myristoyltransferase 1 in tumour development
Published 2023-12-01“…In this review, we discuss the underlying mechanisms by which NMT1 is associated with tumour development from the perspective of oncogene signalling, involvement in cellular metabolism, and endoplasmic reticulum stress. Several NMT inhibitors used in cancer treatment are introduced. …”
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793
Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss
Published 2021-06-01“…Recent studies have shown that telomere dysfunction impairs cellular metabolism, but whether and how these metabolic alterations contribute to liver fibrosis is not well understood. …”
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794
A study of a diauxic growth experiment using an expanded dynamic flux balance framework.
Published 2023-01-01“…Flux balance analysis (FBA) remains one of the most used methods for modeling the entirety of cellular metabolism, and a range of applications and extensions based on the FBA framework have been generated. …”
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795
Connexins and Glucose Metabolism in Cancer
Published 2022-09-01“…Moreover, connexins are able to mediate many aspects of cellular metabolism including the intercellular coupling of nutrients and signaling molecules. …”
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796
The role of hypoxia-inducible factors in tumor angiogenesis and cell metabolism
Published 2017-03-01“…HIF is frequently upregulated in solid tumors, and the overexpression of HIF can promote tumor progression or aggressiveness by blood vessel architecture and altering cellular metabolism. In this review, we focused on the pivotal role of HIF in tumor angiogenesis and energy metabolism. …”
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797
Metabolic Enzymes in Viral Infection and Host Innate Immunity
Published 2023-12-01“…Meanwhile, viruses hijack key cellular metabolic enzymes to reprogram metabolism, which generates the necessary biomolecules for viral replication. …”
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798
Approaches to Formaldehyde Measurement: From Liquid Biological Samples to Cells and Organisms
Published 2022-06-01“…For a long time, FA was considered a “biochemical waste” and a by-product of normal cellular metabolism, but in recent decades the picture has changed. …”
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799
Microbiota-Derived Metabolites in Tumor Progression and Metastasis
Published 2020-08-01“…Microbial communities and human cells, through a dynamic crosstalk, maintain a mutualistic relationship that contributes to the maintenance of cellular metabolism and of the immune and neuronal systems. …”
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800
Dynamics of Mitochondrial Proteome and Acetylome in Glioblastoma Cells with Contrasting Metabolic Phenotypes
Published 2024-03-01“…Glioblastoma, a type of cancer affecting the central nervous system, is characterized by its poor prognosis and the dynamic alteration of its metabolic phenotype to fuel development and progression. Critical to cellular metabolism, mitochondria play a pivotal role, where the acetylation of lysine residues on mitochondrial enzymes emerges as a crucial regulatory mechanism of protein function. …”
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