Feasibility and ethics of using data from the Scottish newborn blood spot archive for research by Sarah Cunningham-Burley, Daniel L. McCartney, Archie Campbell, Robin Flaig, Clare E. L. Orange, Carol Porteous, Mhairi Aitken, Ciaran Mulholland, Sara Davidson, Selena M. McCafferty, Lee Murphy, Nicola Wrobel, Sarah McCafferty, Karen Wallace, David StClair, Shona Kerr, Caroline Hayward, Andrew M. McIntosh, Cathie Sudlow, Riccardo E. Marioni, Jill Pell, Zosia Miedzybrodzka, David J. Porteous

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A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with... by Eric WFW Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James SR Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg, on behalf of the UK Cystic Fibrosis Gene Therapy Consortium

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Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing by Anna J. Stevenson, Daniel L. McCartney, Sarah E. Harris, Adele M. Taylor, Paul Redmond, John M. Starr, Qian Zhang, Allan F. McRae, Naomi R. Wray, Tara L. Spires-Jones, Barry W. McColl, Andrew M. McIntosh, Ian J. Deary, Riccardo E. Marioni

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Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness by Marion Bonneau, Shane T. O’ Sullivan, Miguel A. Gonzalez-Lozano, Paul Baxter, Phillippe Gautier, Elena Marchisella, Neil R. Hardingham, Robert A. Chesters, Helen Torrance, David M. Howard, Maurits A. Jansen, Melanie McMillan, Yasmin Singh, Michel Didier, Frank Koopmans, Colin A. Semple, Andrew M. McIntosh, Hansjürgen Volkmer, Maarten Loos, Kevin Fox, Giles E. Hardingham, Anthony C. Vernon, David J. Porteous, August B. Smit, David J. Price, J. Kirsty Millar

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Genetic, physiological and comparative genomic studies of hypertension and insulin resistance in the spontaneously hypertensive rat by Philip M. Coan, Oliver Hummel, Ana Garcia Diaz, Marjorie Barrier, Neza Alfazema, Penny J. Norsworthy, Michal Pravenec, Enrico Petretto, Norbert Hübner, Timothy J. Aitman

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Complex trait methylation scores in the prediction of major depressive disorder by Miruna C. Barbu, Carmen Amador, Alex S.F. Kwong, Xueyi Shen, Mark J. Adams, David M. Howard, Rosie M. Walker, Stewart W. Morris, Josine L. Min, Chunyu Liu, Jenny van Dongen, Mohsen Ghanbari, Caroline Relton, David J. Porteous, Archie Campbell, Kathryn L. Evans, Heather C. Whalley, Andrew M. McIntosh

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Epigenome-wide association study of global cortical volumes in generation Scotland: Scottish family health study by Miruna Carmen Barbu, Mat Harris, Xueyi Shen, Stolicyn Aleks, Claire Green, Carmen Amador, Rosie Walker, Stewart Morris, Mark Adams, Anca Sandu, Christopher McNeil, Gordon Waiter, Kathryn Evans, Archie Campbell, Joanna Wardlaw, Douglas Steele, Alison Murray, David Porteous, Andrew McIntosh, Heather Whalley

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Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans by Chenhao Gao, Carmen Amador, Rosie M. Walker, Archie Campbell, Rebecca A. Madden, Mark J. Adams, Xiaomeng Bai, Ying Liu, Miaoxin Li, Caroline Hayward, David J. Porteous, Xueyi Shen, Kathryn L. Evans, Chris S. Haley, Andrew M. McIntosh, Pau Navarro, Yanni Zeng

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Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone by Ilhame Diboun, Ilhame Diboun, Sachin Wani, Stuart H. Ralston, Omar M. E. Albagha, Omar M. E. Albagha

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Misestimation of heritability and prediction accuracy of male-pattern baldness by Chloe X. Yap, Julia Sidorenko, Riccardo E. Marioni, Loic Yengo, Naomi R. Wray, Peter M. Visscher

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Adult hypophosphatasia with a novel ALPL mutation: Report of an Indian kindred by Sanjay K. Bhadada, Rimesh Pal, Vandana Dhiman, Nerea Alonso, Stuart H. Ralston, Simran Kaur, Rajat Gupta

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Comprehensive Transcriptomic Profiling of Murine Osteoclast Differentiation Reveals Novel Differentially Expressed Genes and LncRNAs by Salman M. Toor, Sachin Wani, Omar M. E. Albagha, Omar M. E. Albagha

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Editorial: Glucocorticoid and bone: Friend or foe by Ulrike Baschant, Barbara Hauser, Barbara Hauser, Elizabeth Martha Winter

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Editorial: Fish as model organism for skeletal diseases by Erika Kague, Ronald Young Kwon, Ronald Young Kwon, Christoph Winkler

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Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation by Yanni Zeng, Carmen Amador, Charley Xia, Riccardo Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew Bretherick, Oriol Canela-Xandri, Thibaud S. Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Reka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris S. Haley

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DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses by Xueyi Shen, Doretta Caramaschi, Mark J. Adams, Rosie M. Walker, Josine L. Min, Alex Kwong, Gibran Hemani, Genetics of DNA Methylation Consortium, Miruna C. Barbu, Heather C. Whalley, Sarah E. Harris, Ian J. Deary, Stewart W. Morris, Simon R. Cox, Caroline L. Relton, Riccardo E. Marioni, Kathryn L. Evans, Andrew M. McIntosh

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Parent of origin genetic effects on methylation in humans are common and influence complex trait variation by Yanni Zeng, Carmen Amador, Charley Xia, Riccardo Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew Bretherick, Oriol Canela-Xandri, Thibaud S. Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Reka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris S. Haley

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SNP and Haplotype Regional Heritability Mapping (SNHap-RHM): Joint Mapping of Common and Rare Variation Affecting Complex Traits by Richard F. Oppong, Richard F. Oppong, Thibaud Boutin, Archie Campbell, Andrew M. McIntosh, David Porteous, Caroline Hayward, Chris S. Haley, Chris S. Haley, Pau Navarro, Sara Knott

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Corrigendum: When to Start and Stop Bone-Protecting Medication for Preventing Glucocorticoid-Induced Osteoporosis by Kaleen N. Hayes, Ulrike Baschant, Barbara Hauser, Barbara Hauser, Andrea M. Burden, Elizabeth M. Winter

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Local CpG density affects the trajectory and variance of age-associated DNA methylation changes by Jonathan Higham, Lyndsay Kerr, Qian Zhang, Rosie M. Walker, Sarah E. Harris, David M. Howard, Emma L. Hawkins, Anca-Larisa Sandu, J. Douglas Steele, Gordon D. Waiter, Alison D. Murray, Kathryn L. Evans, Andrew M. McIntosh, Peter M. Visscher, Ian J. Deary, Simon R. Cox, Duncan Sproul

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