Cerebrospinal fluid markers to distinguish bacterial meningitis from cerebral malaria in children by Njunge, J, Oyaro, I, Kibinge, N, Rono, M, Kariuki, S, Newton, C, Berkley, J, Gitau, E

“…</p> <h4>Methods</h4> <p>We used label-free protein quantification by mass spectrometry to identify cerebrospinal fluid (CSF) markers that distinguish ABM (n=37) from CM (n=22) in Kenyan children. …”

Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria. by Medana, I, Day, N, Salahifar-Sabet, H, Stocker, R, Smythe, G, Bwanaisa, L, Njobvu, A, Kayira, K, Turner, G, Taylor, T, Hunt, N

“…A retrospective study of 100 Malawian children (87 with malaria and 13 with a diagnosis other than malaria) was conducted to determine the relationship between levels of metabolites of the kynurenine pathway in cerebrospinal fluid (CSF) and disease outcome. Three metabolites were measured: quinolinic acid (QA), an excitotoxin; kynurenic acid (KA), a neuroprotective receptor antagonist; and picolinic acid (PA), a proinflammatory mediator. …”

Nitric oxides in plasma, urine, and cerebrospinal fluid in patients with severe falciparum malaria. by Dondorp, A, Planche, T, de Bel, E, Angus, B, Chotivanich, K, Silamut, K, Romijn, J, Ruangveerayuth, R, Hoek, F, Kager, P, Vreeken, J, White, N

“…The NOx levels in cerebrospinal fluid (CSF) correlated well with plasma NOx levels, but these did not show a correlation with coma depth, and were not significantly different from those in a healthy control group. …”

Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. by Green, J, Tran, C, Farrar, J, Nguyen, M, Nguyen, P, Dinh, S, Ho, N, Ly, C, Tran, H, Friedland, J, Thwaites, G

“…METHODOLOGY/PRINCIPAL FINDINGS: The kinetics of cerebrospinal fluid (CSF) MMP and tissue inhibitors of MMPs (TIMPs) concentrations were studied in a subset of HIV uninfected adults (n = 37) with TBM recruited to a randomized, placebo-controlled trial of adjuvant dexamethasone. …”

Metabolites of the kynurenine pathway of tryptophan metabolism in the cerebrospinal fluid of Malawian children with malaria by Medana, I, Day, N, Salahifar-Sabet, H, Stocker, R, Smythe, G, Bwanaisa, L, Njobvu, A, Kayira, K, Turner, G, Taylor, T, Hunt, N

“…A retrospective study of 100 Malawian children (87 with malaria and 13 with a diagnosis other than malaria) was conducted to determine the relationship between levels of metabolites of the kynurenine pathway in cerebrospinal fluid (CSF) and disease outcome. Three metabolites were measured: quinolinic acid (QA), an excitotoxin; kynurenic acid (KA), a neuroprotective receptor antagonist; a picolinic acid (PA), a proinflammatory mediator. …”

Non-immunoglobin in cerebrospinal fluid of patients with Alzheimer's disease and cerebral amyloid angiopathy. by Esiri, M, Chapel, H, Morton, J, Wilcock, G

Cerebrospinal fluid hypocretin levels are normal in idiopathic REM sleep behaviour disorder. by Anderson, K, Vincent, A, Smith, I, Shneerson, J

“…The control of REM sleep is complex with a putative on/off switch within the brainstem activated, amongst other things, by hypocretinergic pathways from the lateral hypothalamus. METHODS: Cerebrospinal fluid hypocretin levels were measured in five patients with idiopathic RBD. …”

Nonsurgical cerebrospinal fluid rhinorrhea in invasive macroprolactinoma: incidence, radiological, and clinicopathological features. by Suliman, S, Gurlek, A, Byrne, J, Sullivan, N, Thanabalasingham, G, Cudlip, S, Ansorge, O, Wass, J

“…CONTEXT: Macroprolactinomas (MPRLs) may result in nonsurgical (spontaneous or dopamine agonist induced) cerebrospinal fluid (CSF) rhinorrhea; however, the incidence of and mechanisms underlying this phenomenon are poorly understood. …”

Axonal and astrocyte injury markers in the cerebrospinal fluid of Kenyan children with severe malaria. by Medana, I, Idro, R, Newton, C

“…A retrospective study of cerebrospinal fluid (CSF) levels of markers of brain parenchymal damage was conducted in Kenyan children with severe falciparum malaria. …”

Zebrafish cerebrospinal fluid mediates cell survival through a retinoid signaling pathway by Lehtinen, Maria K., Chang, Jessica T., Sive, Hazel L.

“…Cerebrospinal fluid (CSF) includes conserved factors whose function is largely unexplored. …”
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Variation of cerebrospinal fluid in specific regions regulates focality in transcranial direct current stimulation by Kashyap, Rajan, Bhattacharjee, Sagarika, Bharath, Rose Dawn, Venkatasubramanian, Ganesan, Udupa, Kaviraja, Bashir, Shahid, Oishi, Kenichi, Desmond, John E., Chen, Annabel Shen-Hsing, Guan, Cuntai

“…Despite having a uniform tDCS setup, some individuals receive focal stimulation (high DTDI) while others show reduced focality ("non-focal"). The volume of cerebrospinal fluid (CSF), gray matter (GM), and white matter (WM) underlying each ROI govern the tDCS current distribution inside the brain, thereby regulating focality.…”
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Anti-idiotypic sera in the study of cerebrospinal fluid IgG bands in multiple sclerosis. by Ebers, G

Cerebrospinal fluid production - A role for 11 beta-hydroxysteroid dehydrogenase type 1? by Rauz, S, Walker, E, Tomlinson, J, Hughes, S, Wood, P, Stewart, P, Murray, P

The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria by Medana, I, Hien, T, Day, N, Phu, N, Mai, N, Chu'ong, L, Chau, T, Taylor, A, Salahifar, H, Stocker, R, Smythe, G, Turner, G, Farrar, J, White, N, Hunt, N

“…A retrospective study of 261 Vietnamese adults with severe malaria was conducted to determine the relationship between cerebrospinal fluid (CSF) levels of metabolites of the kynurenine pathway, the incidence of neurologic complications, and the disease outcome. …”

Cerebrospinal fluid levels of markers of brain parenchymal damage in Vietnamese adults with severe malaria. by Medana, I, Lindert, R, Wurster, U, Hien, T, Day, N, Phu, N, Mai, N, Chuong, L, Chau, T, Turner, G, Farrar, J, White, N

“…A retrospective study of cerebrospinal fluid (CSF) markers of brain parenchymal damage was conducted in Vietnamese adults with severe malaria. …”

Non-linear relationships of cerebrospinal fluid biomarker levels with cognitive function: an observational study. by Williams, J, Wilcock, G, Seeburger, J, Dallob, A, Laterza, O, Potter, W, Smith, A

“… INTRODUCTION: Levels of cerebrospinal fluid (CSF) β-amyloid (Aβ) and Tau proteins change in Alzheimer's disease (AD). …”

Function of the blood-cerebrospinal fluid barrier in human cerebral malaria: rejection of the permeability hypothesis. by Warrell, D, Looareesuwan, S, Phillips, R, White, N, Warrell, M, Chapel, H, Areekul, S, Tharavanij, S

“…In a group of 157 Thai patients with strictly defined cerebral malaria, cerebrospinal fluid (CSF) opening pressures were normal in 79% and were lower in fatal cases than in survivors (means +/- 1 SD, 144 +/- 58 and 167 +/- 51 mm CSF, respectively, P = 0.051). …”

THE DIURNAL RHYTHM IN CORTICOTROPIN RELEASING HORMONE IS INVERSELY RELATED TO THAT OF CORTISOL IN PRIMATE CEREBROSPINAL-FLUID by Garrick, N, Hill, J, Szele, F, Tomai, T, Gold, P, Murphy, D

The clinical significance of cerebrospinal fluid levels of kynurenine pathway metabolites and lactate in severe malaria. by Medana, I, Hien, T, Day, N, Phu, N, Mai, N, Chu'ong, L, Chau, T, Taylor, A, Salahifar, H, Stocker, R, Smythe, G, Turner, G, Farrar, J, White, N, Hunt, N

“…A retrospective study of 261 Vietnamese adults with severe malaria was conducted to determine the relationship between cerebrospinal fluid (CSF) levels of metabolites of the kynurenine pathway, the incidence of neurologic complications, and the disease outcome. …”

Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone by Whitworth, LJ, Troll, R, Pagán, AJ, Roca, FJ, Edelstein, PH, Troll, M, Tobin, DM, Phu, NH, Bang, ND, Thwaites, GE, Thuong, NTT, Sewell, RF, Ramakrishnan, L

“…Using Bayesian methods, we examined how pretreatment levels of cerebrospinal fluid proinflammatory cytokines affect survival in dexamethasone-treated tuberculous meningitis. …”