S154: IDENTIFICATION OF NOVEL FACTORS CONTROLLING NON GENETIC CELL PLASTICITY IN CHRONIC MYELOID LEUKEMIA by Guido Baselli, Alisa Alekseenko, Eva Brinkman, Yerma Pareja-Sanchez, Lefteris Sinanis, Vicent Pelechano

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Bosutinib: a SRC–ABL tyrosine kinase inhibitor for treatment of chronic myeloid leukemia by El Rassi F, Khoury HJ

“…Bosutinib has shown considerable and sustained efficacy in chronic myeloid leukemia, especially in the chronic phase, with resistance or intolerance to prior tyrosine kinase inhibitors. …”
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COMPARATIVE ASSESSMENT OF ANEMIC SYNDROME IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA ON THE BACKGROUND TO THE GLEEVEC AND HYDREA THERAPY by K.Z. URAKOV, V.YU. MELNIKOVA, G.B. KHODZHIEVA

Subjects: “…chronic myeloid leukemia…”
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PB2478: ASCIMINIB INDUCES ERYTHROPOIESIS IN CHRONIC MYELOID LEUKEMIA CELLS THROUGH DIFFERENTIATION AND NOT BY SELECTION by Hammad Hassan, Areeb Ahmed, Sarah Yousuf, Afsar Mian, El Nasir Lalani

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Incidence and spatial distribution of Chronic Myeloid Leukemia by regions of economic development in the state of Pernambuco, Brazil by Washington Batista das Neves, Ana Maria de Brito, Andreza Pâmela Vasconcelos, Fárida Coeli de Barros Correia Melo, Raul Antônio Morais Melo

“…Background: The establishment of regional development poles in the State of Pernambuco, Brazil was characterized by industrial expansion and consequent concerns about the increase in the occurrence of diseases, specifically those having long latency periods, as is the case of Chronic Myeloid Leukemia. Methods: The study included 367 patients diagnosed with Chronic Myeloid Leukemia over a ten-year period at a reference treatment center. …”
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Assessment of Quality of Life of Chronic Myeloid Leukemia Patients by Using the EORTC QLQ-C30 by Mehmet Can Uğur, Yaşar Bekir Kutbay, Özge Özer Kaya, Cengiz Ceylan

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Continuous therapy response references for BCR::ABL1 monitoring in pediatric chronic myeloid leukemia by Christian Volz, Thomas Zerjatke, Andrea Gottschalk, Sabine Semper, Meinolf Suttorp, Ingmar Glauche, Manuela Krumbholz, Markus Metzler

“…Abstract Response to tyrosine kinase inhibitor (TKI) therapy in patients with chronic myeloid leukemia (CML) is monitored by quantification of BCR::ABL1 transcript levels. …”
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Unrelated Allogeneic Stem Cell Transplantation in a Patient with Chronic Myeloid Leukemia in Blast Crisis by Benedek István, Lázár Erzsébet, Köpeczi Judit Beáta, Benedek István, Tunyogi Aliz Beáta, Jakab Szende, Pakucs Annamária

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Frequency of BCR-ABL 1 Fusion Transcripts Variants in Chronic Myeloid Leukemia Algerian patients by Mourad NACHI, Ibtissem KIHEL, Badra ENTASOLTAN, Karima TAIBI, Djaouad GUELLA, Amine ABED, Yasmine BOUKHATMI, Mohamed-Amine BEKADJA

Subjects: “…Chronic Myeloid Leukemia…”
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Meta-Analysis of Gastrointestinal Adverse Events from Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia by Prahathishree Mohanavelu, Mira Mutnick, Nidhi Mehra, Brandon White, Sparsh Kudrimoti, Kaci Hernandez Kluesner, Xinyu Chen, Tim Nguyen, Elaina Horlander, Helena Thenot, Vamsi Kota, Cassie S. Mitchell

Subjects: “…chronic myeloid leukemia…”
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Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth. by Haixia Zhou, Yue Ge, Lili Sun, Wenjuan Ma, Jie Wu, Xiuyan Zhang, Xiaohui Hu, Connie J Eaves, Depei Wu, Yun Zhao

“…Although the generation of BCR-ABL is the molecular hallmark of chronic myeloid leukemia (CML), the comprehensive molecular mechanisms of the disease remain unclear yet. …”
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PB1897: DISCONTINUATION OF IMATINIB IN PATIENTS FOLLOWED FOR CHRONIC MYELOID LEUKEMIA IN DEEP MOLECULAR RESPONSE by Y. Bouchakor Moussa, S. Taoussi, S. Oukid, F. Lamraoui, N. Rekab, K. M. Benlabiod, H. Brahimi, M. T. Abad, M. Bradai

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Adverse outcomes for chronic myeloid leukemia patients with splenomegaly and low in vivo kinase inhibition on imatinib by Chung H. Kok, Verity A. Saunders, Phuong Dang, Naranie Shanmuganathan, Deborah White, Susan Branford, David Yeung, Timothy P. Hughes

“…Abstract Variability in the molecular response to frontline tyrosine kinase inhibitor (TKI) therapy in chronic myeloid leukemia may be partially driven by differences in the level of kinase inhibition induced. …”
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A rare case of B-lymphoid blast phase of chronic myeloid leukemia: Diagnostic challenges by Nada Naiyer, MD, Ann-Leslie Zaslav, PhD, Tahmeena Ahmed, MD, Silvia Spitzer, PhD, Yupo Ma, MD, Roxanna Ponce, Htien Lee, Hong Lin, PhD

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Inhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia by Dan Wang, Huan Yang, Yun Zhang, Rong Hu, Dongjie Hu, Qunxian Wang, Yannan Liu, Mingjing Liu, Zijun Meng, Weihui Zhou, Weihong Song

“…Our study suggests that inhibition of CBS induces cell apoptosis, as well as limits cell proliferation and migration, a potential target for the treatment of chronic myeloid leukemia.…”
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Effect of imatinib on plasma glucose concentration in subjects with chronic myeloid leukemia and gastrointestinal stromal tumor by Miguel Ángel Gómez-Sámano, Jorge Enrique Baquerizo-Burgos, Melissa Fabiola Coronel Coronel, Buileng Daniela Wong-Campoverde, Fernando Villanueva-Martinez, Diego Molina-Botello, Jose Alonso Avila-Rojo, Lucía Palacios-Báez, Daniel Cuevas-Ramos, Francisco Javier Gomez-Perez, Alejandro Zentella-Dehesa, Álvaro Aguayo-González, Alfonso Gulias-Herrero

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Expression of Bcl-2 protein and the amplification of c-myc gene in patients with chronic myeloid leukemia by Strnad Milica, Brajušković Goran, Strelić Nataša, Živanović-Todorić Biljana, Tukić Ljiljana, Stamatović Dragana

“…Background/Aim. Chronic myeloid leukemia (CML) represents a malignant myeloproliferative disease developed out of pluripotent hematopoietic stem cell that contains the fusion bcr-abl gene. …”
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Chronic Myeloid Leukemia with Vitreous Body and Fundus Hemorrhage Caused by Imatinib: A Case Report by WU Na, Qi Lin, CHENG Zhiyong, DING Yueling, ZHOU Xiaodai, XIE Yangyang, ZHAO Yaling

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Tyrosine Kinase Inhibitors in pediatric chronic myeloid leukemia: a focused review of clinical trials by Fateen Ata, Maria Benkhadra, Rola Ghasoub, Liam J. Fernyhough, Nabil E. Omar, Nabil E. Omar, Abdulqadir J. Nashwan, Mahmood B. Aldapt, Kamran Mushtaq, Nancy A. Kassem, Mohamed A. Yassin

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CDA gene silencing regulated the proliferation and apoptosis of chronic myeloid leukemia K562 cells by Xiao-Fang Wei, You-Fan Feng, Qiao-Lin Chen, Qi-Ke Zhang

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