Performance characteristics of the first Food and Drug Administration (FDA)-cleared digital droplet PCR (ddPCR) assay for BCR::ABL1 monitoring in chronic myelogenous leukemia. by Dawne N Shelton, Prasanthi Bhagavatula, Nathan Sepulveda, Lan Beppu, Shital Gandhi, Dahui Qin, Scott Hauenstein, Jerald Radich

“…Chronic myelogenous leukemia (CML) is a hematopoietic stem cell malignancy that accounts for 15-20% of all cases of leukemia. …”
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A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells by Patricia Martín-Rodríguez, Borja Guerra, Idaira Hueso-Falcón, Haidee Aranda-Tavío, Juan Díaz-Chico, José Quintana, Francisco Estévez, Bonifacio Díaz-Chico, Angel Amesty, Ana Estévez-Braun, Leandro Fernández-Pérez

“…BCR-ABL1-STAT5 is an oncogenic signaling pathway in human chronic myelogenous leukemia (CML) and it represents a valid target for anti-CML drug design. …”
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Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-Abl by Cao Qi, Li Juan, Chen Chun, Jin Yanli, Lu Zhongzheng, Pan Jingxuan

“…<p>Abstract</p> <p>Background</p> <p>Chronic myelogenous leukemia (CML) is characterized by the chimeric tyrosine kinase Bcr-Abl. …”
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Differential diagnosis from isolated lymphoid extramedullary blast crisis from secondary non-Hodgkin lymphoma in chronic myelogenous leukemia: a case report and literature review by Tingting Wang, Li Fu, Na Wei, Xiaoge Zhou, Xiaodan Zheng, Li Li, Zhao Wang

Subjects: “…chronic myelogenous leukemia…”
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S159: QUÉBEC CML RESEARCH GROUP ANALYSIS OF TREATMENT PATTERNS IN CHRONIC MYELOGENOUS LEUKEMIA: SWITCHING IS DRIVEN BY INTOLERANCE AND SIMILAR ACROSS TYROSINE KINASE INHIBITORS AND LINES OF TREATMENT by L. Busque, M. Harnois, N. Szuber, R. Delage, L. Mollica, H. Olney, P. Laneuville, S. Sirhan, G. Cournoyer, I. Chamakhi, M. Lalancette, D. Talbot, V. Éthier, P. Desjardins, S. Assouline

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Abnormal imaging presentations of extramedullary hematopoiesis in a 21-year old and 72-year old female by Alexander Kaechele, DO, Aruj Chawla, DO, Matthew Osher, MD

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Induction of Apoptosis in K562 Leukemia Cells Upon Exposure to a Derivative from 4-aryl-4H Chromenes Family by M.H. Naseri, S. Hesami Tackallou, M. Mahdavi, M.A. Moosavi, S. Abasalti, A. Foroumadi, A. Hadizade

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Pulmonary arterial hypertension in a patient treated with dasatinib: a case report by Andris Skride, Matiss Sablinskis, Kristaps Sablinskis, Krista Lesina, Aivars Lejnieks, Sandra Lejniece

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Bilateral Maxillary, Sphenoid Sinuses and Lumbosacral Spinal Cord Extramedullary Relapse of CML Following Allogeneic Stem Cell Transplant by Soudabeh Hosseini, Shahla Ansari, Parvaneh Vosough, Gholamreza Bahoush, Morteza Shamsizadeh, Mitra Mehrazma, Akbar Dorgalaleh

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Correction to: Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-κB signaling and depleting Bcr-Abl by Zhongzheng Lu, Yanli Jin, Chun Chen, Juan Li, Qi Cao, Jingxuan Pan

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ANALYSIS OF THE FUNCTIONAL STATE OF MAIN TRANSPORT SYSTEMS OF BLOOD PLASMA OF PATIENTS WITH ACUTE LEUKEMIA AND CHRONIC MYELOGENOUS LEUKEMIA AFTER TRANSPLANTATION THE HEMATOPOIETIC STEM CELLS BY FLUORESCENT PROBES METHOD by E. V. Korolik, A. A. Ivanov, N. I. Insarova, O. M. Morozova, N. F. Milanovich, A. L. Uss

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Design, Synthesis and Biological Evaluation of Pentacyclic Triterpene Derivatives: Optimization of Anti-ABL Kinase Activity by Halil I. Ciftci, Mohamed O. Radwan, Safiye E. Ozturk, N. Gokce Ulusoy, Ece Sozer, Doha E. Ellakwa, Zeynep Ocak, Mustafa Can, Taha F.S. Ali, Howaida I. Abd-Alla, Nurettin Yayli, Hiroshi Tateishi, Masami Otsuka, Mikako Fujita

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Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms by Xiaoying Lan, Chong Zhao, Xin Chen, Peiquan Zhang, Dan Zang, Jinjie Wu, Jinghong Chen, Huidan Long, Li Yang, Hongbiao Huang, Bing Z. Carter, Xuejun Wang, Xianping Shi, Jinbao Liu

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Case report: Long-term voluntary Tyrosine Kinase Inhibitor (TKI) discontinuation in chronic myeloid leukemia (CML): Molecular evidence of an immune surveillance by Jusuf Imeri, Christophe Desterke, Christophe Desterke, Paul Marcoux, Diana Chaker, Diana Chaker, Noufissa Oudrhiri, Noufissa Oudrhiri, Noufissa Oudrhiri, Noufissa Oudrhiri, Xavier Fund, Xavier Fund, Jamila Faivre, Jamila Faivre, Annelise Bennaceur-Griscelli, Annelise Bennaceur-Griscelli, Annelise Bennaceur-Griscelli, Annelise Bennaceur-Griscelli, Ali G. Turhan, Ali G. Turhan, Ali G. Turhan, Ali G. Turhan

Subjects: “…chronic myelogenous leukemia…”
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AS1041, a novel derivative of marine natural compound Aspergiolide A, induces senescence of leukemia cells via oxidative stress-induced DNA damage and BCR-ABL degradation by Xuxiu Lu, Fengli Yuan, Liang Qiao, Yankai Liu, Qianqun Gu, Xin Qi, Jing Li, Dehai Li, Ming Liu

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Frequency of the BCR/ABL rearrangements and associated alterations detected by FISH during monitoring of patients taking imatinib mesylate in isolation Freqüência do rearranjo BCR/... by Cristina B. Vendrame-Goloni, Andréa B. Carvalho-Salles, Octávio Ricci Júnior, Carlos E. Miguel, Agnes C. Fett-Conte

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CircRNA Microarray Profiling Reveals hsa_circ_0058493 as a Novel Biomarker for Imatinib-Resistant CML by An-Ni Zhong, An-Ni Zhong, An-Ni Zhong, Yi Yin, Yi Yin, Bing-Jie Tang, Bing-Jie Tang, Lei Chen, Lei Chen, Hong-Wei Shen, Zhi-Ping Tan, Wen-Qun Li, Wen-Qun Li, Qun He, Bao Sun, Bao Sun, Yan Zhu, Yan Zhu, Yan Zhu, Jie Xiao, Jie Xiao, Zhi-Ping Jiang, Ping Xu, Ping Xu

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The Involvement of Canonical NFκB Pathway in Megakaryocyte Differentiation Induction by Nanocurcumin by Seyedeh Sahar Mortazavi Farsani, Dina Sadeghizadeh, Sadegh Babashah, Fariba Rad, Majid Sadeghizadeh

Subjects: “…Megakaryopoiesis; Nanocurcumin; NFκB pathway; Chronic Myelogenous Leukemia (CML)…”
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PB1972: ASC4START: A PHASE IIIB, OPEN-LABEL, RANDOMIZED STUDY OF ASCIMINIB VERSUS NILOTINIB IN PATIENTS WITH NEWLY DIAGNOSED PH+ CHRONIC MYELOGENOUS LEUKEMIA IN CHRONIC PHASE by Andreas Hochhaus, Susanne Saussele, Francois-Xavier Mahon, Virginia Pilipovic, Yifan Zhang, Peter Schuld, Tim H Brümmendorf

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Tyrosine kinase inhibitors therapy related neutropenia and thrombocythopenia correction in CML patients by V. A. Shuvaev, M. S. Fominykh, I. S. Martynkevich, V. Y. Udaleva, N. A. Potikhonova, M. N. Zenina, K. M. Abdulkadyrov

Subjects: “…chronic myelogenous leukemia…”
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