Low HLA binding of diabetes-associated CD8+ T-cell epitopes is increased by post translational modifications by John Sidney, Jose Luis Vela, Dave Friedrich, Ravi Kolla, Matthias von Herrath, Johnna D. Wesley, Alessandro Sette

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Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity by Matthew J. Benskey, Rhyomi C. Sellnow, Ivette M. Sandoval, Ivette M. Sandoval, Caryl E. Sortwell, Caryl E. Sortwell, Jack W. Lipton, Jack W. Lipton, Fredric P. Manfredsson, Fredric P. Manfredsson

Subjects: “…major histocompatibility complex class 1 (MHC-1)…”
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Human Cytomegalovirus variant peptides adapt by decreasing their total coordination upon binding to a T cell receptor by Georgios S.E. Antipas, Anastasios E. Germenis

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Association between NDO-LID and PGL-1 for leprosy and class I and II human leukocyte antigen alleles in an indigenous community in Southwest Amazon by Stéfanie Ferreira Teles, Eliane Aparecida Silva, Rodrigo Medeiros de Souza, Jane Tomimori, Marcos Cesar Florian, Rogério Oliveira Souza, Elaine Valim Camarinha Marcos, Fabiana Covolo de Souza-Santana, Mônica Antar Gamba

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The quantum chemical causality of pMHC-TCR biological avidity: Peptide atomic coordination data and the electronic state of agonist N termini by Georgios S.E. Antipas, Anastasios E. Germenis

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Axons are injured by antigen-specific CD8+ T cells through a MHC class I- and granzyme B-dependent mechanism by Brian M. Sauer, William F. Schmalstieg, Charles L. Howe

Subjects: “…Major histocompatibility complex class I (MHC I)…”
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Expressão de antígenos MHC classe I e de células CD4 e CD8 na polimiosite e dermatomiosite by Carla Renata Graça, João Aris Kouyoumdjian

Subjects: “…Antígenos de complexo principal de histocompatibilidade classe I (MHC-I)…”
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The risks of using allogeneic cell lines for vaccine production: the example of Bovine Neonatal Pancytopenia by Lindert Benedictus, Charlotte R. Bell

Subjects: “…major histocompatibility complex class i (mhc i)…”
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Bypassing anti-PD-(L)1 therapy: Mechanisms and management strategies by Keywan Mortezaee, Jamal Majidpoor, Sajad Najafi, Davood Tasa

Subjects: “…Major histocompatibility complex class I (MHC-I)…”
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Pomalidomide increases immune surface marker expression and immune recognition of oncovirus-infected cells by David A. Davis, Prabha Shrestha, Ashley I. Aisabor, Alexandra Stream, Veronica Galli, Cynthia A. Pise-Masison, Takanobu Tagawa, Joseph M. Ziegelbauer, Genoveffa Franchini, Robert Yarchoan

Subjects: “…major histocompatibility complex class i (mhc-i)…”
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Enhanced recognition of human NK receptors after influenza virus infection. by Achdout, H, Arnon, T, Markel, G, Gonen-Gross, T, Katz, G, Lieberman, N, Gazit, R, Joseph, A, Kedar, E, Mandelboim, O

“…Surprisingly, however, no change in the level of class I MHC protein expression was observed on the surface of the infected cells. …”

Tight Regulation of Major Histocompatibility Complex I for the Spatial and Temporal Expression in the Hippocampal Neurons by Yuqing Shen, Yuqing Shen, Jianqiong Zhang, Jianqiong Zhang, Jianqiong Zhang

“…Since several previous reviews have addressed the roles of class I MHC in the formation and function of hippocampal connections, the present review will focus on describing the spatial and temporal expression of class I MHC in developing, healthy adult, and aging hippocampus. …”
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Recognition of HLA-Cw4 but not HLA-Cw6 by the NK cell receptor killer cell Ig-like receptor two-domain short tail number 4. by Katz, G, Markel, G, Mizrahi, S, Arnon, T, Mandelboim, O

“…NK cells are cytotoxic to virus-infected and tumor cells that have lost surface expression of class I MHC proteins. Target cell expression of class I MHC proteins inhibits NK cytotoxicity through binding to inhibitory NK receptors. …”

A defect in the presentation of intracellular viral antigens is restored by interferon-gamma in cell lines with impaired major histocompatibility complex class I assembly. by Sibille, C, Gould, K, Hämmerling, G, Townsend, A

“…To define other factors involved in class I MHC assembly, we have studied two tumor cell lines that are deficient in cell surface class I (H-2) expression. …”

Classical and nonclassical class I major histocompatibility complex molecules exhibit subtle conformational differences that affect binding to CD8alphaalpha. by Gao, G, Willcox, B, Wyer, JR, Boulter, J, O'Callaghan, C, Maenaka, K, Stuart, D, Jones, E, Van Der Merwe, P, Bell, J, Jakobsen, B

“…We suggest such affinities apply to most CD8alphaalpha/classical class I MHC interactions and may be optimal for T-cell recognition. …”

Immunoinformatic evaluation of the cross-presentation of donor major histocompatibility derived epitopes by recipient major histocompatibility class i molecules in transplantation... by Suhana Koothradan, K K Elyas

“…Results: The ability of the selected class I MHC molecule, human leukocyte antigens (HLAs)-A* 11:01, considered the donor allele, to act as an exogenous antigen and to get processed into peptides and presented on the second class I MHC molecule, HLA-A*02:01, considered the recipient allele was confirmed. …”
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A three-colour flow cytometry technique for measuring trophoblast intracellular antigens: the relative expression of TAP1 in human cytotrophoblast and decidual cells. by Clover, L, Coghill, E, Redman, C, Sargent, I

“…Villous and extravillous cytotrophoblast were identified in first trimester and term placental and decidual digests on the basis of their expression of cytokeratin and Class I MHC antigens. The level of expression of TAP1 for each population was investigated using a commercial kit that determines the number of antibody-binding sites per cell. …”

Creating HIV-1 reverse transcriptase cytotoxic T lymphocyte target structures by HLA-A2 heavy chain modifications. by Dela Cruz, C, Tan, R, Rowland-Jones, S, Barber, B

“…It is known that the display of high levels of class I MHC-viral peptide complexes at the cell surface of target cells is necessary to elicit a strong CTL response. …”

Stability of empty and peptide-loaded class II major histocompatibility complex molecules at neutral and endosomal pH: comparison to class I proteins. by Reich, Z, Altman, J, Boniface, J, Lyons, D, Kozono, H, Ogg, G, Morgan, C, Davis, M

“…In contrast, of four class I MHC molecules studied, three have shown a significant loss in complex stability at low pH. …”

HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2. by Hill, AB, Barnett, B, McMichael, A, McGeoch, D

“…To assess the effect of herpes simplex virus (HSV) on assembly and transport of class I MHC molecules, we compared class I MHC immunoprecipitated from metabolically labeled infected and uninfected human dermal fibroblasts. …”