Showing 1 - 20 results of 336 for search '"Class I MHC"', query time: 1.55s Refine Results
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    Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion. by Ahmad Bakur Mahmoud, Megan M Tu, Andrew Wight, Haggag S Zein, Mir Munir A Rahim, Seung-Hwan Lee, Harman S Sekhon, Earl G Brown, Andrew P Makrigiannis

    Published 2016-02-01
    “…Like human KIR, Ly49 receptors inhibit NK cell-mediated lysis by binding to major histocompatibility complex class I (MHC-I) molecules that are expressed on normal cells. …”
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    Promiscuous binding of extracellular peptides to cell surface class I MHC protein by Eisen, Herman N., Hou, Xun Helen, Shen, Chase, Wang, Kaidi, Tanguturi, Varsha Keelara, Smith, Crysela, Kozyrytska, Katerina, Nambiar, Lakshmi, McKinley, Carol A., Chen, Jianzhu, Cohen, Richard J.

    Published 2012
    “…Algorithms derived from measurements of short-peptide (8–10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K[superscript b], can bind well over 1 million different peptides with significant affinity (<500 nM), a level of ligand-binding promiscuity approaching the level of heat shock protein binding of unfolded proteins. …”
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    Promiscuous binding of extracellular peptides to cell surface class I MHC protein by Eisen, Herman N., Hou, Xun Helen, Shen, Chase, Wang, Kaidi, Tanguturi, Varsha Keelara, Smith, Crysela, Kozyrytska, Katerina, Nambiar, Lakshmi, McKinley, Carol A., Chen, Jianzhu, Cohen, Richard J.

    Published 2012
    “…Algorithms derived from measurements of short-peptide (8–10 mers) binding to class I MHC proteins suggest that the binding groove of a class I MHC protein, such as K[superscript b], can bind well over 1 million different peptides with significant affinity (<500 nM), a level of ligand-binding promiscuity approaching the level of heat shock protein binding of unfolded proteins. …”
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    Intragraft selection of the T cell receptor repertoire by class I MHC sequences in tolerant recipients. by Dahai Liu, Xiu-Da Shen, Yuan Zhai, Wengsi Lam, Jingying Liao, Ronald W Busuttil, Rafik M Ghobrial

    Published 2009-06-01
    “…BACKGROUND:Allograft tolerance of ACI (RT1(a)) recipients to WF (RT1(u)) hearts can be induced by allochimeric class I MHC molecules containing donor-type (RT1A(u)) immunogenic epitopes displayed on recipient-type (RT1A(a)) sequences. …”
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    A method to quantify binding of unlabeled peptides to class I MHC molecules and detect their allele specificity. by Elvin, J, Potter, C, Elliott, T, Cerundolo, V, Townsend, A

    Published 1993
    “…A general method has been developed for measuring the stabilization of class I MHC molecules in extracts of the mutant cell lines .174/T2 and RMA-S. 35S-Met-labeled class I molecules which have been stabilized by peptides in vitro are immunoprecipitated with conformation dependent monoclonal antibodies and electrophoresed on polyacrylamide gels. …”
    Journal article
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    Characterization of a nonclassical class I MHC gene in a reptile, the Galápagos marine iguana (Amblyrhynchus cristatus). by Scott Glaberman, Louis Du Pasquier, Adalgisa Caccone

    Published 2008-01-01
    “…Here, we use both cDNA and genomic sequence data to characterize a class I MHC gene (Amcr-UA) from the Galápagos marine iguana, a member of the squamate subfamily Iguaninae. …”
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    Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models by Flower Darren R, Xu Qiqi, Meng Xiangshan, Liu Wen, Li Tongbin

    Published 2006-03-01
    “…When applied to MHC-peptide binding data for three mouse class I MHC alleles, the SVRMHC models produced more accurate predictions than those produced previously. …”
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    Vaccine-induced antibodies linked to bovine neonatal pancytopenia (BNP) recognize cattle major histocompatibility complex class I (MHC I) by Deutskens Fabian, Lamp Benjamin, Riedel Christiane M, Wentz Eveline, Lochnit Günter, Doll Klaus, Thiel Heinz-Jürgen, Rümenapf Till

    Published 2011-08-01
    “…The presence of major histocompatibility complex class I (MHC I) in the vaccine was confirmed by Western blot using a MHC I specific monoclonal antibody. …”
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    CD66a interactions between human melanoma and NK cells: a novel class I MHC-independent inhibitory mechanism of cytotoxicity. by Markel, G, Lieberman, N, Katz, G, Arnon, T, Lotem, M, Drize, O, Blumberg, R, Bar-Haim, E, Mader, R, Eisenbach, L, Mandelboim, O

    Published 2002
    “…NK cells are able to kill virus-infected and tumor cells via a panel of lysis receptors. Cells expressing class I MHC proteins are protected from lysis primarily due to the interactions of several families of NK receptors with both classical and nonclassical class I MHC proteins. …”
    Journal article
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    Forming the base population of fast-growing African catfish (Clarias gariepinus) carrying major histocompatibility complex class I (MHC I) allele through a within-family selection by Iswanto Bambang, Marnis Huria, Suprapto Rommy, Imron

    Published 2023-01-01
    “…The base population consisted of two populations, each resulting from a factorial mating design of a 2:2 ratio between 30 males and 30 females of Mutiara African catfish carrying major histocompatibility complex class I (MHC I) allele number 7. Forming the first base population resulted in 50 families, whereas the second resulted in 57 families. …”
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