Determination of β-Agonists in Urine Samples at Low µg/kg Levels by Means of Pulsed Amperometric Detection at a Glassy Carbon Electrode Coupled with RP-LC by Annalisa Mentana, Carmen Palermo, Diego Centonze

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Drug-induced acute pancreatitis in a bodybuilder: a case report by Seyed Ali Safizadeh Shabestari, Samuel B. Ho, Priyadarshini Chaudhary, Rahul A. Nathwani

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Efficacy, Safety and Mechanism of Jinzhen Oral Liquid in the Treatment of Acute Bronchitis in Children: A Randomized, Double-Blind, Multicenter Clinical Trial Protocol by Xin Cui, Long Liang, Hongjiao Geng, Yi Liu, Junyu Xi, Junhong Wang, Tee Bee Ching, Eow Gaik Bee, Yan Chai, ShengXian Wu, De Jin, YanMing Xie

Subjects: “…Ambroxol Hydrochloride and Clenbuterol Hydrochloride Oral Solution (AHCHOS)…”
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β-Adrenoceptor agonists enhance 5-hydroxytryptamine-mediated behavioural responses by Cowen, P, Grahame-Smith, D, Green, A, Heal, D

“…The β-adrenoceptor agonists, salbutamol, terbutaline and clenbuterol, were investigated for their effect on 5-hydroxytryptamine-mediated (5-HT) hyperactivity. …”

beta-Adrenoceptor agonists enhance 5-hydroxytryptamine-mediated behavioural responses. by Cowen, P, Grahame-Smith, D, Green, A, Heal, D

“…The beta-adrenoceptor agonists, salbutamol, terbutaline and clenbuterol, were investigated for their effect on 5-hydroxytryptamine-mediated (5-HT) hyperactivity. 2 The lipophilic beta-adrenoceptor agonist, clenbuterol (5 mg/kg) enhanced the behaviours induced by quipazine (25 mg/kg), including headweaving, forepaw treading and hind-limb abduction and thus increased automated activity recording. …”

Determination of 4 Kinds of β-Agonists Residues in Braised Meat by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry by Chunyang MENG, Yutian WU, Lei PENG, Xue ZHONG, Lu ZOU, Wenzheng LIU, Yibing ZHOU

“…An ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS) method was developed for the determination of four β-agonists (terbutaline, clenbuterol, ractopamine, salbutamol) in braised meat. …”
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 β2-Adrenergic receptor agonist ameliorates phenotypes and corrects microRNA-mediated IGF1 deficits in a mouse model of Rett syndrome by Mellios, Nikolaos, Woodson, Jonathan, Garcia, Rodrigo, Crawford, Benjamin, Sharma, Jitendra, Sheridan, Steven, Sur, Mriganka, Haggarty, Stephen J.

“…Finally, cotreatment with clenbuterol and recombinant human IGF1 results in additional increases in survival in male null mice. …”
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Pulsed Amperometry for Anti-fouling of Boron-doped Diamond in Electroanalysis of β-Agonists: Application to Flow Injection for Pharmaceutical Analysis by Duangjai Nacapricha, Oraphan Anurukvorakun, Leena Suntornsuk, Orawon Chailapakul, Yasuaki Einaga, Piyada Jittangprasert, Kate Grudpan, Prapin Wilairat, Patcharin Chaisuwan, Thitirat Mantim, Chanpen Karuwan

“…This work presents the construction and application of boron-doped diamond(BDD) thin film electrode as sensor for the determination of three β-agonists, viz.salbutamol, terbutaline and clenbuterol. Although well-known as a chemically inertmaterial, BDD film however shows fouling in detection of these compounds using fixedpotentialmode amperometry. …”
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Construction of SERS chip based on silver nanoparticles and detection of sports doping β-agonists by Mingzhi Ye, Sheng Tang

“…This study focuses on the development of a surface-enhanced Raman spectroscopy (SERS) chip for the detection of β-agonists, such as clenbuterol, ractopamine, and salbutamol, which are commonly abused as performance-enhancing drugs. …”
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Determination of β₂-Agonist Residues in Fermented Ham Using UHPLC-MS/MS after Enzymatic Digestion and Sulfonic Resin Solid Phase Purification by Chenggang Cai, Yannan Xiang, Siyi Tian, Zhongce Hu, Zhengyan Hu, Bingjie Ma, Pinggu Wu

“…This newly developed method was applied to the detection of β₂-agonist residues in 50 commercial ham products and only one sample was found to contain β₂-agonist residues (clenbuterol at 15.2 µg/kg).…”
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Application of Improved Electrochemical Sensor in Food Safety Inspection by Jingna Shi, Shiying Yang

“…This paper analyzes the detection mechanism of electrochemical sensor by integrating nanotechnology with electrochemical analysis, and achieves excellent detection results after applying the proposed method to detect the clenbuterol (CB) and chloramphenicol (CAP) in food. …”
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C-Reactive Protein (CRP) Blocks the Desensitization of Agonistic Stimulated G Protein Coupled Receptors (GPCRs) in Neonatal Rat Cardiomyocytes by Gerd Wallukat, Stephan Mattecka, Katrin Wenzel, Wieland Schrödl, Birgit Vogt, Patrizia Brunner, Ahmed Sheriff, Rudolf Kunze

“…All used agonists (isoprenaline, clenbuterol, phenylephrine, angiotensin II and endothelin 1) affected the beat rate of cardiomyocytes significantly and after washing them out and re-stimulation the cells developed a pronounced desensitization of the corresponding receptors. …”
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Role of β-adrenergic signaling in masseter muscle. by Aiko Ito, Yoshiki Ohnuki, Kenji Suita, Misao Ishikawa, Yasumasa Mototani, Kouichi Shiozawa, Naoya Kawamura, Yuka Yagisawa, Megumi Nariyama, Daisuke Umeki, Yoshiki Nakamura, Satoshi Okumura

“…Therefore, in this work, we compared the effects of chronic β1- or β2-AR activation with a specific β1-AR agonist, dobutamine (DOB), or a specific β2-AR agonist, clenbuterol (CB), on masseter and cardiac muscles in mice. …”
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Research on Rapid Detection Technology for <i>β</i>₂-Agonists: Multi-Residue Fluorescence Immunochromatography Based on Dimeric Artificial Antigen by Miaomiao Liu, Biao Ma, Yaping Wang, Erjing Chen, Jiali Li, Mingzhou Zhang

“…To detect two types of <i>β</i>₂-agonist residues at the same time, we coupled two haptens of clenbuterol (CLE) and ractopamine (RAC) to the same carrier protein through diazotization to prepare dimeric artificial antigen, and a fluorescent lateral flow immunoassay method based on europium nanoparticles (EuNP-FLFIA) was established by combining polyclonal antibodies with europium nanoparticles to form probes. …”
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Comparison and applicability of Agilent EMR-Lipid and Captiva EMR-Lipid Sorbents in QuEChERS method for food analysis by Quang Hoang Hanh Le, Nguyen Ngoc Chau Tran, Thi Cam Tuyen Nguyen, Huong Giang Nguyen, Kien Trieu Lac, Thi Anh Pham, Pham Ngoc Son Chu

“…These queries are answered in our present communication concerning the analytes Trifluralin (logP: 5.27), Fipronil (logP: 4.0), and Clenbuterol (logP: 2.63). …”
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Gendered perspectives on women’s anabolic–androgenic steroid (AAS) usage practices by Tim Piatkowski, Jonathan Robertson, Severine Lamon, Matthew Dunn

“…Oxandrolone) as well as other PIEDs (e.g. Clenbuterol). Some women report the use of injectable AAS represents a change in the profile of the typical female user as it reportedly comes alongside drastic physical and psychological changes. …”
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Determination of bisphenol A in water bottles by spectrophotometric method by Razak, Nur Syuhada Abd

“…The analysis of BpA was carried out by diazotizing the clenbuterol with sodium nitrite before coupled them with BpA to form an azo-compound in ammonia-ammonium chloride buffer. …”
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Glaucoma and Alzheimer: Neurodegenerative disorders show an adrenergic dysbalance. by Bettina Hohberger, Harald Prüss, Christian Mardin, Robert Lämmer, Johannes Müller, Gerd Wallukat

“…Moreover, the long chain Aß1-40, Aβ1-42, and Aβ10-37, yet not the short-chain Aß peptides prevented the clenbuterol induced desensitization of the ß2-AR. In addition, we identified functional autoantibodies in the sera of AD patients, activating the ß2-AR, like the ß2-agAAb found in patients with glaucoma. …”
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Determination of β₂-Agonist Residues in Meat Samples by Gas Chromatography-Mass Spectrometry with N-Doped Carbon Dots in Molecular Sieves by Shanshan Zhu, Binglin Mou, Liao Zheng, Luhong Wen, Ning Gan, Lin Zheng

“…A simple, effective, and highly sensitive analytical approach was created and applied in this study for the accurate measurement of three β₂-agonist residues (clenbuterol, salbutamol, and ractopamine) in meat samples. …”
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Efficacy of Acetylshikonin in Preventing Obesity and Hepatic Steatosis in db/db Mice by Mei-Ling Su, Yu He, Qi-Sen Li, Bang-Hao Zhu

“…Mice were divided into Wild Type (WT) groups and db/db groups, which received no treatment or treatment with 100 mg/kg/day clenbuterol (CL) hydrochloride or 540 mg/kg/day AS by oral gavage for eight weeks. …”
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