Liver-Specific <i>Bmal1</i> Depletion Reverses the Beneficial Effects of Nobiletin on Liver Cholesterol Homeostasis in Mice Fed with High-Fat Diet by Zhitian Lu, Xudong Li, Min Wang, Xiaojun Zhang, Runxuan Zhuang, Fan Wu, Wenxue Li, Wei Zhu, Bo Zhang

“…However, the requirement of specific clock genes for the beneficial effects of NOB is not well understood. …”
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Feeding strategy trade-off and selection of marine nocturnal gastropods under predation risk by Shihui Lin, Shihui Lin, Xiaolong Gao, Xiaolong Gao, Mo Zhang, Mo Zhang, Mingxin Lyu, Mingxin Lyu, Caihuan Ke, Caihuan Ke

“…Correlation analysis shows that the expression levels of Bmal1 and Clock had significantly positive correlations with the circadian changes in the movement parameters of the abalone, thereby suggesting a dominant role in the rhythmic expression of endogenous circadian clock genes regulating the rhythmic behavior of the abalone. …”
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The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specif... by Brooke M. Van Loh, Alexandra M. Yaw, Joseph A. Breuer, Brooke Jackson, Duong Nguyen, Krystal Jang, Fabiola Ramos, Emily V. Ho, Laura J. Cui, Dominique L. M. Gillette, Lorenzo F. Sempere, Michael R. Gorman, Michael R. Gorman, Karen J. Tonsfeldt, Karen J. Tonsfeldt, Pamela L. Mellon, Pamela L. Mellon, Hanne M. Hoffmann, Hanne M. Hoffmann

“…On a molecular level, the shortening of the SCN period was driven, at least partially, by a direct regulatory role of VAX1 on the circadian clock genes Bmal1 and Per2. Interestingly, Vax1Vip females presented with increased expression of arginine vasopressin (Avp) in the paraventricular nucleus, which resulted in increased circulating corticosterone. …”
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Genetic deletion of Kvβ2 (AKR6) causes loss of muscle function and increased inflammation in mice by Ravikumar Manickam, Jazmine Virzi, Anish Potti, Feng Cheng, David W. Russ, Srinivas M. Tipparaju

“…Analysis of RNA Seq data of the gastrocnemius muscles (GAS) identified significant increase in genes involved in skeletal muscle development, proliferation and cell fate determination, atrophy, energy metabolism, muscle plasticity, inflammation, and a decrease in circadian core clock genes in young Kvβ2 KO vs. WT mice. Several genes were significantly upregulated (384 genes) and downregulated (40 genes) in young Kvβ2 KO mice compared to age-matched WT mice. …”
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