The CIRCuiTS study (Implementation of cognitive remediation in early intervention services): protocol for a randomised controlled trial by Wykes, T, Joyce, E, Velikonja, T, Watson, A, Aarons, G, Birchwood, M, Cella, M, Dopson, S, Fowler, D, Greenwood, K, Johnson, S, McCrone, P, Perez, J, Pickles, A, Reeder, C, Rose, D, Singh, S, Stringer, D, Taylor, M, Taylor, R, Upthegrove, R

“…A psychological treatment known as cognitive remediation therapy (CRT) aims to improve cognition in neuropsychiatric disorders, with the ultimate goal of improving functional recovery. …”

Cognitive rehabilitation in schizophrenia research: a bibliometric and visualization analysis by Xiaofeng Shu, Yubin Dai, Juanping Tang, Yi Huang, Rong Hu, Yong Lin

“…Additionally, the neurobiological foundations of cognitive remediation therapy constitute an unexplored territory ripe for further investigation.…”
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Efficacy of cognitive training on cognition, symptoms and functioning: Impact of motivation and attendance by Joanna M. Fiszdon, Kaicheng Wang, Karen Lê, Lori Parente, Jimmy Choi

“…While cognitive remediation therapy (CRT) and compensatory strategy training both have large literature bases supporting their efficacy on both proximal and distal outcomes, the research base on stand-alone cognitive training (CT) is smaller and less consistent, with little information about factors associated with better outcomes. …”
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Intervention Programmes for First-Episode Psychosis: A Scoping Review by Marta Gouveia, Tânia Morgado, Tiago Costa, Francisco Sampaio, Amorim Rosa, Carlos Sequeira

“…The results showed that there is a great deal of variety in the characteristics of the programmes, with interventions ranging from single-component strategies, such as cognitive–behavioural therapy (CBT) and cognitive remediation therapy (CRT), to multicomponent programmes that integrate a number of different approaches, including psychosocial, pharmacological, and family-focused strategies. …”
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Factors affecting cognitive remediation outcome in schizophrenia: The role of treatment resistance by M. Spangaro, M. Bosia, F. Martini, M. Bechi, M. Buonocore, R. Cavallaro

“…Different studies showed that TRS patients exhibit poorer neurocognitive performance, particularly on verbal domains. To date Cognitive Remediation Therapy (CRT) represents the best available tool for treating cognitive deficits in schizophrenia. …”
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A Short Course Computer-assisted Cognitive Remediation in Patients with Schizophrenia Spectrum Disorders: A Randomized Clinical Trial by Samira Hatami, Zahra Mirsepassi, Azadeh Sedighnia, Mehdi Tehranidoost, Maryam Masoomi, Vandad Sharifi

“…Introduction: Cognitive Remediation Therapy (CRT) is used to improve cognitive functioning in patients with Schizophrenia Spectrum Disorders (SSDs). …”
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The clock is ticking on schizophrenia: a study protocol for a translational study integrating phenotypic, genomic, microbiome and biomolecular data to overcome disability by Giacomo Mercuriali, Lorenzo Lodde, Lorenzo Lodde, Pasquale Paribello, Pasquale Paribello, Jacopo Sapienza, Alice Corona, Alice Corona, Chiara Ave, Delia Pacini, Delia Pacini, Daniela Nocera, Carolina Corrias, Carolina Corrias, Sabrina El Kacemi, Sabrina El Kacemi, Michele D'Incalci, Ilaria Frau, Ilaria Frau, Elena Monzani, Flavia Valtorta, Flavia Valtorta, Donatella Congiu, Anna Meloni, Maria Scherma, Paola Fadda, Simona Dedoni, Carlotta Siddi, Stefania Sut, Stefano Dall’Acqua, Sofia Nasini, Benedetta Barzon, Alessio Squassina, Roberto Cavallaro, Roberto Cavallaro, Mirko Manchia, Mirko Manchia, Mirko Manchia, Claudia Pisanu, Marta Bosia, Marta Bosia, Stefano Comai, Stefano Comai, Stefano Comai, Stefano Comai

“…Additionally, we plan to assess the impact of a 3-month cognitive remediation therapy on 30 of these patients. We will analyze clinical data alongside serum biomarkers and gene expression related to the Trp- to MLT and Kyn metabolic pathways, markers of inflammatory and composition of the gut microbiome. …”
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Cognitive Behavioral and Cognitive Remediation Strategies for Managing Co-Occurring Anorexia Nervosa and Elevated Autism Spectrum Traits by Saure E, Ålgars M, Laasonen M, Raevuori A

“…The purpose of this narrative review was to investigate the feasibility of cognitive remediation therapy (CRT), cognitive remediation and emotional skill training (CREST), and cognitive behavioral therapy (CBT), and give an overview of treatment modifications for individuals with AN and co-occurring ASD or high ASD traits. …”
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Cognitive remediation in schizophrenia: What happens after 10 years? by Mariachiara Buonocore, Marco Spangaro, Margherita Bechi, Stefania Trezzani, Rachele Terragni, Francesca Martini, Giulia Agostoni, Federica Cocchi, Federica Cuoco, Carmelo Guglielmino, Marta Bosia, Roberto Cavallaro

“…Cognitive Remediation Therapy (CRT) represents the gold standard treatment for cognitive impairment in schizophrenia, but the permanence of its effects over time have been poorly investigated. …”
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« Cognitus & Moi » : a computer-based cognitive remediation program for children with intellectual disability by Caroline eDemily, Caroline eDemily, Caroline eRigard, Caroline eRigard, Elodie ePeyroux, Elodie ePeyroux, Elodie ePeyroux, Gabrielle eChesnoy-Servanin, Aurore eMorel, Aurore eMorel, Nicolas eFranck, Nicolas eFranck

“…The heterogeneity of cognitive deficits in intellectual deficiency necessitates an individualized cognitive remediation therapy. In this regard, « Cognitus & Moi » seems to be a promising tool.…”
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Feasibility of six-month outpatient cognitive remediation in schizophrenia: Experience from the randomized controlled integrated social cognition and social skills therapy study by Tim Schuster, Agnes Lowe, Karolin Weide, Daniel Kamp, Mathias Riesbeck, Andreas Bechdolf, Anke Brockhaus-Dumke, René Hurlemann, Ana Muthesius, Stefan Klingberg, Martin Hellmich, Sabine Schmied, Andreas Meyer-Lindenberg, Wolfgang Wölwer

“…Patients with schizophrenia often have cognitive impairments that contribute to diminished psychosocial functioning. Cognitive remediation therapy (CRT) has proven efficacy and is recommended by evidence-based treatment guidelines. …”
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Improving Cognition to Increase Treatment Efficacy in Schizophrenia: Effects of Metabolic Syndrome on Cognitive Remediation's Outcome by Marta Bosia, Marta Bosia, Mariachiara Buonocore, Margherita Bechi, Laura Santarelli, Marco Spangaro, Federica Cocchi, Carmelo Guglielmino, Laura Bianchi, Serena Bringheli, Francesca Bosinelli, Roberto Cavallaro, Roberto Cavallaro

“…However, results are still contradictory and no study has so far examined the influence of metabolic syndrome on cognitive outcome after cognitive remediation therapy (CRT). Based on these premises, this study aims to investigate the relationship between metabolic syndrome and cognition, specifically considering cognitive outcome after treatment. …”
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Comparative efficacy and acceptability of psychological interventions for the treatment of adult outpatients with anorexia nervosa: a systematic review and network meta-analysis by Solmi, M, Wade, TD, Byrne, S, Del Giovane, C, Fairburn, CG, Ostinelli, EG, De Crescenzo, F, Johnson, C, Schmidt, U, Treasure ,J, Favaro, A, Zipfel, S, Cipriani, A

“…The primary outcomes were the change in body mass index and clinical symptoms, and the secondary outcome was all-cause dropout rate, which were all assessed for treatment as usual, cognitive behavioural therapy (CBT), Maudsley anorexia treatment for adults, family-based treatment, psychodynamic-oriented psychotherapies, a form of CBT targeting compulsive exercise, and cognitive remediation therapy followed by CBT. Global and local inconsistencies for the network meta-analysis were measured, and CINeMA was used to assess the confidence in evidence for primary outcomes. …”

CONNEX, a Phase III Randomized Trial Program Assessing Efficacy and Safety of Iclepertin in Schizophrenia: Recruitment and Baseline Characteristics by Zuzana Blahova, Satoru Ikezawa, Peter Falkai, John H. Krystal, Tarun Rangan

“…Patients with cognitive impairment due to developmental, neurological or other disorders, or receiving cognitive remediation therapy ≤12 weeks before screening will be excluded. …”
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The Phase III CONNEX programme assessing the efficacy and safety of iclepertin in patients with schizophrenia: Trial design and recruitment update by C. Reuteman-Fowler, Z. Blahova, S. Ikezawa, S. Marder, P. Falkai, J. H. Krystal

“…Patients with cognitive impairment due to developmental, neurological or other disorders, with a current DSM-5 diagnosis other than schizophrenia or receiving cognitive remediation therapy within 12 weeks prior to screening, will be excluded. …”
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Neuroinflammation and kynurenines in schizophrenia: Impact on cognition depending on cognitive functioning and modulatory properties in relation to cognitive remediation and aerobi... by Jacopo Sapienza, Giulia Agostoni, Stefano Comai, Sofia Nasini, Stefano Dall'Acqua, Stefania Sut, Marco Spangaro, Francesca Martini, Margherita Bechi, Mariachiara Buonocore, Giorgia Bigai, Federica Repaci, Daniela Nocera, Chiara Ave, Carmelo Guglielmino, Federica Cocchi, Roberto Cavallaro, Giacomo Deste, Marta Bosia

“…Moreover, we studied their possible link to the cognitive outcome in relation to sessions of cognitive remediation therapy (CRT) and aerobic exercise (AE) in a longitudinal arm of 42 patients. …”
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Efficacy and safety of iclepertin (BI 425809) in patients with schizophrenia: CONNEX, a Phase III randomised controlled trial programme by P. Falkai, C. Reuteman-Fowler, Z. Blahova, S. Ikezawa, S. R. Marder, J. H. Krystal

“…Pts with CI due to developmental, neurological or other disorders, or receiving cognitive remediation therapy within 12 wks prior to screening, will be excluded. …”
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Monitoring of dyadic conversations : a social signal processing approach by Yasir Tahir

“…The interviews of the patients enrolled in an observational study on the effectiveness of Cognitive Remediation Therapy (CRT) are analyzed. The subjects comprise schizophrenic patients undergoing CRT treatment, and the control group consists of schizophrenic patients not undergoing CRT. …”
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Discussion on Assessment and Treatment of Cognitive Impairment and New Developments of Cognitive Remediation in Schizophrenia by T. Wykes

“…The importance of these cognitive impairments for choosing specific or generic cognitive remediation therapies will be highlighted as well as the need to consider social cognition and metacognition as potentially more important ingredients for improving recovery.…”
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The role of genetics in cognitive remediation in schizophrenia: A systematic review by Rafael Penadés, Marta Bosia, Rosa Catalán, Marco Spangaro, Clemente García-Rizo, Silvia Amoretti, Miquel Bioque, Miquel Bernardo

“…The role of genetics in cognitive remediation therapies in schizophrenia has not been completely understood yet. …”
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