Cross-species transcriptomics reveals bifurcation point during the arterial-to-hemogenic transition by Shaokang Mo, Kengyuan Qu, Junfeng Huang, Qiwei Li, Wenqing Zhang, Kuangyu Yen

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Truncating tau reveals different pathophysiological actions of oligomers in single neurons by Emily Hill, Thomas K. Karikari, Juan Lantero-Rodriguez, Henrik Zetterberg, Kaj Blennow, Magnus J. Richardson, Mark J. Wall

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A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cells by Yuan Lin, Xue Wang, Yuhao Qin, Chengpan Wang, Tang Zhou, Long Zhang, Lu Su, Wenming Ren, Cheng Liao

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Genome-wide CRISPR screen for HSV-1 host factors reveals PAPSS1 contributes to heparan sulfate synthesis by Takeshi Suzuki, Yoshitaka Sato, Yusuke Okuno, Fumi Goshima, Tadahisa Mikami, Miki Umeda, Takayuki Murata, Takahiro Watanabe, Koichi Watashi, Takaji Wakita, Hiroshi Kitagawa, Hiroshi Kimura

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Archaeopteryx feather sheaths reveal sequential center-out flight-related molting strategy by Thomas G. Kaye, Michael Pittman, William R. Wahl

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Spatiotemporal biocontrol and rhizosphere microbiome analysis of Fusarium wilt of banana by Zhiyan Zhu, Guiyun Wu, Rufang Deng, Xiaoying Hu, Haibo Tan, Yaping Chen, Zhihong Tian, Jianxiong Li

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Chitosan functionalized Mn3O4 nanoparticles counteracts ulcerative colitis in mice through modulation of cellular redox state by Susmita Mondal, Monojit Das, Ria Ghosh, Manali Singh, Aniruddha Adhikari, Soumendra Darbar, Anjan Kumar Das, Siddhartha Sankar Bhattacharya, Debasish Pal, Debasish Bhattacharyya, Ahmed S. A. Ahmed, Asim Kumar Mallick, Munirah M. Al-Rooqi, Ziad Moussa, Saleh A. Ahmed, Samir Kumar Pal

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Meta-connectomic analysis maps consistent, reproducible, and transcriptionally relevant functional connectome hubs in the human brain by Zhilei Xu, Mingrui Xia, Xindi Wang, Xuhong Liao, Tengda Zhao, Yong He

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A thermodynamic investigation of amyloid precursor protein processing by human γ-secretase by Xiaoli Lu, Jing Huang

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Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family by Peter J. Stogios, Emily Bordeleau, Zhiyu Xu, Tatiana Skarina, Elena Evdokimova, Sommer Chou, Luke Diorio-Toth, Alaric W. D’Souza, Sanket Patel, Gautam Dantas, Gerard D. Wright, Alexei Savchenko

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Early alterations of large-scale brain networks temporal dynamics in young children with autism by Aurélie Bochet, Holger Franz Sperdin, Tonia Anahi Rihs, Nada Kojovic, Martina Franchini, Reem Kais Jan, Christoph Martin Michel, Marie Schaer

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Nanopore long-read RNA sequencing reveals functional alternative splicing variants in human vascular smooth muscle cells by Hao Wu, Yicheng Lu, Zhenzhen Duan, Jingni Wu, Minghui Lin, Yangjun Wu, Siyang Han, Tongqi Li, Yuqi Fan, Xiaoyuan Hu, Hongyan Xiao, Jiaxuan Feng, Zhiqian Lu, Deping Kong, Shengli Li

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A selectivity filter mutation provides insights into gating regulation of a K+ channel by Theres Friesacher, Haritha P. Reddy, Harald Bernsteiner, J. Carlo Combista, Boris Shalomov, Amal K. Bera, Eva-Maria Zangerl-Plessl, Nathan Dascal, Anna Stary-Weinzinger

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Structural insights into ribonucleoprotein dissociation by nucleocapsid protein interacting with non-structural protein 3 in SARS-CoV-2 by Xincheng Ni, Yinze Han, Renjie Zhou, Yanmei Zhou, Jian Lei

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Architectural basis for cylindrical self-assembly governing Plk4-mediated centriole duplication in human cells by Jong Il Ahn, Liang Zhang, Harsha Ravishankar, Lixin Fan, Klara Kirsch, Yan Zeng, Lingjun Meng, Jung-Eun Park, Hye-Yeoung Yun, Rodolfo Ghirlando, Buyong Ma, David Ball, Bonsu Ku, Ruth Nussinov, Jeremy D. Schmit, William F. Heinz, Seung Jun Kim, Tatiana Karpova, Yun-Xing Wang, Kyung S. Lee

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BayesR3 enables fast MCMC blocked processing for largescale multi-trait genomic prediction and QTN mapping analysis by Edmond J. Breen, Iona M. MacLeod, Phuong N. Ho, Mekonnen Haile-Mariam, Jennie E. Pryce, Carl D. Thomas, Hans D. Daetwyler, Michael E. Goddard

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TIPARP is involved in the regulation of intraocular pressure by Youjia Zhang, Maomao Song, Yingwen Bi, Yuan Lei, Xinghuai Sun, Yuhong Chen

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TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress by Hiroyuki Ueno, Takuya Hoshino, Wakako Yano, Sayaka Tsukioka, Takamasa Suzuki, Shoki Hara, Yoshio Ogino, Khoon Tee Chong, Tatsuya Suzuki, Shingo Tsuji, Hikaru Itadani, Ikuo Yamamiya, Yoshihiro Otsu, Satoshi Ito, Toshiya Yonekura, Miki Terasaka, Nozomu Tanaka, Seiji Miyahara

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Prolonged fixation and post-mortem delay impede the study of adult neurogenesis in mice by M. Gallardo-Caballero, C. B. Rodríguez-Moreno, L. Álvarez-Méndez, J. Terreros-Roncal, M. Flor-García, E. P. Moreno-Jiménez, A. Rábano, M. Llorens-Martín

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Long-term hematopoietic stem cells as a parasite niche during treatment failure in visceral leishmaniasis by Laura Dirkx, Sarah Hendrickx, Margot Merlot, Dimitri Bulté, Marick Starick, Jessy Elst, André Bafica, Didier G. Ebo, Louis Maes, Johan Van Weyenbergh, Guy Caljon

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