Metal Cluster Triggered-Assembling Heterogeneous Au-Ag Nanoclusters with Highly Loading Performance and Biocompatible Capability by Xiaoxiao He, Xiaohong Ma, Yujun Yang, Xi Hu, Teng Wang, Shiyue Chen, Xiang Mao

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Biocompatibility of the oxygen carrier polymerized human hemoglobin towards HepG2/C3A cells by Nuozhou Chen, Donald A. Belcher, Chintan Savla, Andre F. Palmer, Francois Berthiaume

“…The toxicity of these compounds toward liver cells must be evaluated before testing their use in these complex systems for oxygen delivery. Herein, we characterized the effect of PolyHbs on the hepatoma cell line HepG2/C3A, used as a model hepatocyte and as a cell line used in some investigational bioartificial liver support devices. …”
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Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors by Santiago Schiaffino-Ortega, Elena Mariotto, Pilar María Luque-Navarro, María Kimatrai-Salvador, Pablo Rios-Marco, Ramon Hurtado-Guerrero, Carmen Marco, María Paz Carrasco-Jimenez, Giampietro Viola, Luisa Carlota López-Cara

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Projecting sediment export from two highly glacierized alpine catchments under climate change: exploring non-parametric regression as an analysis tool by L. K. Schmidt, T. Francke, P. M. Grosse, A. Bronstert

“…Yet, quantitative projections of future sediment export have so far been hindered by the lack of process-based models that can take into account all relevant processes within the complex systems determining sediment dynamics at the catchment scale. …”
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What do we not know (yet) about recovery colleges? A study protocol on their (cost-)effectiveness, mechanisms of action, fidelity and positioning by Marloes M. C. van Wezel, Christien Muusse, Dike van de Mheen, Ben Wijnen, Wouter den Hollander, Hans Kroon

“…Moreover, we will gather data on a micro level (i.e., impact on RC students), meso level (i.e., organisational fidelity) and macro level (i.e., positioning in the care and support domain), capturing all important perspectives when scrutinizing the impact of complex systems. Finally, we will demonstrate the validity and value of embracing experiential knowledge in science as a complementary source of information, leading to a more profound understanding of what is researched. …”
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The impact of inter-organizational alignment (IOA) on implementation outcomes: evaluating unique and shared organizational influences in education sector mental health by Aaron R. Lyon, Kelly Whitaker, Jill Locke, Clayton R. Cook, Kevin M. King, Mylien Duong, Chayna Davis, Mark D. Weist, Mark G. Ehrhart, Gregory A. Aarons

“…In addition to improving school-based mental health, these findings will spur future implementation science that considers the relationships across organizations and optimize the capacity of implementation science to guide practice in increasingly complex systems of care.…”
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Information cascade prediction of complex networks based on physics-informed graph convolutional network by Dingguo Yu, Yijie Zhou, Suiyu Zhang, Wenbing Li, Michael Small, Ke-ke Shang

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A comprehensive numerical study on the fluid flow, thermal and exergetic performance of longitudinally ribbed spirally coiled tube with various shapes by Dan Wang, Theyab R. Alsenani, Pradeep Kumar Singh, Raymond Ghandour, Hamad Almujibah, Saleem Anwar Khan, Rashid Ali, Thanh Tuan Le, Fatma Aouaini, Dao Nam Cao

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Elucidating disease-associated mechanisms triggered by pollutants via the epigenetic landscape using large-scale ChIP-Seq data by Zhaonan Zou, Yuka Yoshimura, Yoshihiro Yamanishi, Shinya Oki

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Quantitative assessment of the potential of retail outlets by K. A. Lychagin

“…Today  the paradigm  of open complex systems is used to simulate and analyze the mechanisms and processes of interaction  of agents in the market  environment. …”
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Strategizing the National Economy during a Period of Burgeoning Technological Sovereignty by V. L. Kvint, I. V. Novikova, M. K. Alimuradov, N. I. Sasaev

“…The scientific research is based on the general theory of Strategy and strategizing methodology developed by the Center for Strategic Research at the Institute of Mathematical Research of Complex Systems and the Economic and Financial Strategy Department at Moscow School of Economics at Lomonosov Moscow State University with the leadership of Foreign Member of the Russian Academy of Sciences, professor Vladimir L. …”
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Sex-specific adipose tissue’s dynamic role in metabolic and inflammatory response following peripheral nerve injury by Valentina Vacca, Claudia Rossi, Luisa Pieroni, Federica De Angelis, Giacomo Giacovazzo, Ilaria Cicalini, Domenico Ciavardelli, Flaminia Pavone, Roberto Coccurello, Sara Marinelli

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Integration of SysML and Virtual Reality Environment: A Ground Based Telescope System Example by Mostafa Lutfi, Ricardo Valerdi

“…In recent years, Model Based Systems Engineering (MBSE) has continued to develop as a standard for designing, managing, and maintaining increasingly complex systems. Unlike the document centric approach, MBSE puts the model at the heart of system design. …”
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TXNL4B regulates radioresistance by controlling the PRP3‐mediated alternative splicing of FANCI by Zhao Ju, Jing Xiang, Liang Xiao, Yan He, Le Zhang, Yin Wang, Ridan Lei, Yunfeng Nie, Long Yang, Justyna Miszczyk, Pingkun Zhou, Ruixue Huang

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Self-assembled chitosan-sodium usnate drug delivery nanosystems: Synthesis, characterization, stability studies, in vitro cytotoxicity and in vivo biocompatibility against 143 B ce... by Benedetta Brugnoli, Alessia Mariano, Beatrice Simonis, Cecilia Bombelli, Simona Sennato, Antonella Piozzi, Vincenzo Taresco, Veeren M. Chauhan, Steven M. Howdle, Anna Scotto d'Abusco, Iolanda Francolini

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Using dynamic modelling to enhance the assessment of the beef water footprint by H.M. Menendez, III, A. Atzori, J. Brennan, L.O. Tedeschi

“…It is extremely difficult to identify policy interventions (i.e., management strategies) for complex systems, like the U.S. beef cattle system, because there are many actors (i.e., cow-calf, stocker, feedlot) and interrelated variables that have delayed effects within and across the supply chain. …”
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A multi-source data approach to carbon stock prediction using Bayesian hierarchical geostatistical models in plantation forest ecosystems by Tsikai S. Chinembiri, Onisimo Mutanga, Timothy Dube

“…Bayesian modeling is presumed to be the best approach for modeling such complex systems. Using a Bayesian hierarchical inferential framework, we employed a multi-source data approach (i.e. remote sensing derived anthropogenic, climatic and topographic set of variables) to model Carbon (C) stock in a managed plantation forest ecosystem in Zimbabwe’s Eastern Highlands. …”
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Data-driven approach for labelling process plant event data by Debora Corrêa, Adriano Polpo, Michael Small, Shreyas Srikanth, Kylie Hollins, Melinda Hodkiewicz

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Immune status characteristics in patients with hormonal disorders and undifferentiated connective tissue dysplasia by Chikisheva A.A.

“…<br> <br> <b>Key words: </b>immune status, connective tissue dysplasia, immunoglobulins, circulating immune complexes, systemic enzyme therapy.<br> <b>For citation: </b>Ilina I.Yu., Dobrokhotova Yu.E., Chikisheva A.A., Malikova V.O. …”
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Using Information and Communication Technologies to Engage Citizens in Health System Governance in Burkina Faso: Protocol for Action Research by Sandrine Biau, Emmanuel Bonnet, Christian Dagenais, Manuela De Allegri, Zoumana Traoré, Abdoul Wahabo Ouedraogo, Abdramane Sow, Karina Dubois-Nguyen, Valéry Ridde

“… BackgroundHealth systems are complex systems involving a vast range of actors. In West Africa, they are often not accessible or responsive. …”
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