Nanozyme-reinforced hydrogel as a H₂O₂-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy by Zhao, Yue, Song, Shanliang, Wang, Dongdong, Liu, He, Zhang, Junmin, Li, Zuhao, Wang, Jincheng, Ren, Xiangzhong, Zhao, Yanli

Get full text

Gasdermin D-deficient mice are hypersensitive to acute kidney injury by Tonnus, Wulf, Maremonti, Francesca, Belavgeni, Alexia, Latk, Markus, Kusunoki, Yoshihiro, Brucker, Anne, Mässenhausen, Anne von, Meyer, Claudia, Locke, Sophie, Gembardt, Florian, Beer, Kristina, Hoppenz, Paul, Becker, Jan U., Hugo, Christian, Anders, Hans-Joachim, Bornstein, Stefan R., Shao, Feng, Linkermann, Andreas

Get full text

Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrati... by Sarah M. Bell, Jacquelyn M. Evans, Katy M. Evans, Kate L. Tsai, Rooksana E. Noorai, Thomas R. Famula, Dolores M. Holle, Leigh Anne Clark

“…Across dogs and wolves, the major allele includes two copies of the repeat, whereas the predominant alleles in GSDs have one or three copies. …”
Get full text

Analysis of Issues and Challenges of Copyright of Textual Digital Resources from the Viewpoint of Managers of Academic Digital Libraries in Tehran by Sima Amouzgar, Alireza Noruzi, Maryam Sarrafzadeh

“…Indicators of the nature of digital environment in order of importance were: the ease of unauthorized sharing of copyrighted works simultaneously among multiple users; the ease of scientific and literary manipulation (plagiarism); the ambiguity of responsibility and the right to protect the digital content by digital libraries; the ease of copy and paste of digital texts; the distortion and dissemination of copyrighted materials; the problem of validating the authenticity of digital content; the possibility of unauthorized reproduction at the international level; the inaccurate identification of the production site and the publisher of the work; and failure to identify the provenance and publisher of digital content.Conclusion: The challenge of defective copyright laws is the most important problem facing the copyright of textual digital resources. …”
Get full text

Mouse modifiers of intestinal tumorigenesis by Hong, Karen H. (Karen Hsiao-Ying), 1971-

Get full text

Vývoj a validace diagnostického real-time PCR systému pro detekci Olive latent viru 1 (OLV-1) v rostlinách jahodníku by Lucie Valentová

“…Sensitivity of the detection was assessed to be 50 copies per reaction; 500 copies per reaction was used to calculate other parameters. …”
Get full text

Theaflavins Improve Insulin Sensitivity through Regulating Mitochondrial Biosynthesis in Palmitic Acid-Induced HepG2 Cells by Tuantuan Tong, Ning Ren, Park Soomi, Jiafan Wu, Na Guo, Hyunuk Kang, Eunhye Kim, Yuanyuan Wu, Puming He, Youying Tu, Bo Li

“…In this research, we investigated the protective effects of theaflavins against insulin resistance in HepG2 cells induced by palmitic acid. …”
Get full text

Low-Concentration T-2 Toxin Attenuates Pseudorabies Virus Replication in Porcine Kidney 15 Cells by Kuankuan Xiong, Lei Tan, Siliang Yi, Yingxin Wu, Yi Hu, Aibing Wang, Lingchen Yang

“…Similarly, T2 significantly decreased the copy number of PRV. Investigation of the mechanism revealed that 10 nM T2 significantly inhibits PRV replication and leads to downregulation of oxidative stress- and apoptosis-related genes. …”
Get full text

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality by Dai, Lingyun, Prabhu, Nayana, Diam, Go Ka, Sobota, Radoslaw, Larsson, Andreas, Nordlund, Pär, McCormick, Frank, Ghosh, Sujoy, Epstein, David M., Dymock, Brian W., Lee, Sang Hyun, Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Shang, See Cheng, Minami, Noriaki, Sampetrean, Oltea, Saya, Hideyuki

Get full text
Get full text

Deletions in Genes Participating in Innate Immune Response Modify the Clinical Course of Andes Orthohantavirus Infection by Grazielle Esteves Ribeiro, Luis Edgardo Leon, Ruth Perez, Analia Cuiza, Pablo Agustin Vial, Marcela Ferres, Gregory J. Mertz, Cecilia Vial

“…For this, the frequency of copy number variants (CNVs, i.e., deletions and duplications) was studied in 195 patients, 88 with mild and 107 with severe HCPS. …”
Get full text

CTSH regulates : cell function and disease progression in newly diagnosed type 1 diabetes patients by Reinheckel, Thomas, Herrath, Matthias von, Fløyel, Tina, Brorsson, Caroline, Nielsen, Lotte B., Miani, Michela, Bang-Berthelsen, Claus Heiner, Friedrichsen, Martin, Overgaard, Anne Julie, Berchtold, Lukas A., Wiberg, Anna, Poulsen, Pernille, Hansen, Lars, Rosinger, Silke, Boehm, Bernhard O., Ram, Ramesh, Nguyen, Quang, Mehta, Munish, Morahan, Grant, Concannon, Patrick, Bergholdt, Regine, Nielsen, Jens H., Vaag, Allan, Eizirik, Decio Laks, Mortensen, Henrik B., Størling, Joachim, Pociot, Flemming

Get full text
Get full text

Infant dietary patterns and early childhood caries in a multi-ethnic Asian cohort by Hu, Shijia, Sim, Yu Fan, Toh, Jia Ying, Saw, Seang Mei, Godfrey, Keith M., Chong, Yap-Seng, Yap, Fabian, Lee, Yung Seng, Shek, Lynette Pei-Chi, Tan, Kok Hian, Chong, Mary Foong-Fong, Hsu, Stephen Chin-Ying

Get full text
Get full text

Hydrogen sulfide is an endogenous regulator of aging in Caenorhabditis elegans by Qabazard, Bedoor, Li, Ling, Gruber, Jan, Peh, Meng Teng, Ng, Li Fang, Dinesh Kumar, Srinivasan, Rose, Peter, Tan, Choon-Hong, Dymock, Brian W., Wei, Feng, Swain, Suresh C., Halliwell, Barry, Stürzenbaum, Stephen R., Moore, Philip K.

Get full text
Get full text

Papain-like cysteine proteases in Carica papaya: lineage-specific gene duplication and expansion by Juan Liu, Anupma Sharma, Marie Jamille Niewiara, Ratnesh Singh, Ray Ming, Qingyi Yu

“…Papain, the first cysteine protease whose structure was determined by X-ray crystallography, plays a crucial role in protecting papaya from herbivorous insects. Except the four major PLCPs purified and characterized in papaya latex, the rest of the PLCPs in papaya genome are largely unknown. …”
Get full text

Tethering of Epidermal Growth Factor (EGF) to Beta Tricalcium Phosphate (βTCP) via Fusion to a High Affinity, Multimeric βTCP-Binding Peptide: Effects on Human Multipotent Stromal... by Alvarez, Luis M., Rivera, Jaime J., Stockdale, Linda, Saini, Sunil, Lee, Richard T., Griffith, Linda G.

“…Previous studies using EGF tethered to synthetic polymer substrates have demonstrated that surface-tethered EGF can protect human bone marrow-derived osteogenic stem and progenitor cells from pro-death inflammatory cues and enhance their proliferation without detriment to subsequent osteogenic differentiation. …”
Get full text
Get full text

Long-Term Serological Response to 13-Valent Pneumococcal Conjugate Vaccine Versus 23-Valent Polysaccharide Vaccine in HIV-Infected Adults by Simone Belmonti, Barbara Rossetti, Sara Modica, Lorenzo Paglicci, Alberto Borghetti, Arturo Ciccullo, Chiara Picarelli, Roberto Cauda, Andrea De Luca, Francesca Montagnani, Francesca Lombardi

“…Comparison of immunogenicity was based on geometric mean concentration (GMC), proportion of individuals with ≥ twofold increase from BL in specific antibody concentration against ≥ 2 serotypes and percentage of individuals with serotype-specific IgG ≥ 0.35 μg/ml, ≥ 1 μg/ml and ≥ individual serotype-specific correlates of protection. Results We included 91 subjects (median CD4+ 650 cells/µl, > 90% with HIV-RNA < 50 copies/ml); patients in groups 1 (n = 42) and 2 (n = 49) were homogeneous for the main characteristics. …”
Get full text

Prevention of media inspired copycat crime in Malaysia: A legal analysis / Muhammad Arif Azmi … [et al.] by Azmi, Muhammad Arif, Saiful Madzi, Shireen Munira, Yusof, Zulhazmi, M. Yusoff, Muhammad Azzamudeen

“…We believe that there needs to be protection from mediums that can allow unsolicited television programs or film to be viewed.…”
Get full text

Phytoplasma and phytoplasma diseases: a review of recent research by A. Bertaccini, B. Duduk

Get full text

Molecular Analysis of the Pathway for the Synthesis of Thiol Tripeptides in the Model Legume Lotus japonicus by Manuel A. Matamoros, Maria R. Clemente, Shusei Sato, Erika Asamizu, Satoshi Tabata, Javier Ramos, Jose F. Moran, Jiri Stiller, Peter M. Gresshoff, Manuel Becana

“…The thiol tripeptides, glutathione (GSH) and homoglu-tathione (hGSH), perform multiple roles in legumes, including protection against toxicity of free radicals and heavy metals. …”
Get full text

Biosimilars: potential implications for clinicians by Eleryan MG, Akhiyat S, Rengifo-Pardo M, Ehrlich A

“…In contrast to generics, which are exact copies of their original products, biosimilars are not identical to their reference products. …”
Get full text