CpG island structure and trithorax/polycomb chromatin domains in human cells by Orlando, David A., Guenther, Matthew G., Frampton, Garrett M., Young, Richard A.

“…We find that in pluripotent cells, clustered CpG-islands at genes predict occupancy of H3K4me3 and H3K27me3, and these "bivalent" chromatin domains precisely span the boundaries of CpG-island clusters. …”
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Toward stable gene expression in CHO cells Preventing promoter silencing with core CpG island elements by Mariati, Koh, Esther YC, Yeo, Jessna HM, Ho, Steven CL, Yang, Yuansheng

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Insertion of core CpG island element into human CMV promoter for enhancing recombinant protein expression stability in CHO cells by Mariati, Yeo, Jessna H. M., Koh, Esther Y. C., Ho, Steven C. L., Yang, Yuansheng

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The effect of budesonide and 5-azacytidine on the levels of methylation at the CpG islands of human choline kinase alpha (ckα) and beta (ckβ) promoter by Rahman, Muhammad Al Bunyamin Abdul

“…Analysis of all fourteen ckα and ckβ promoter CpG island regions could give clearer information on both ckα and ckβ promoter CpG island methylation status after the treatment of epigenetic drugs.…”
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HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy by JnBaptiste, Courtney Kenneil, Michaud, Joelle, Praz, Viviane, James Faresse, Nicole, Tyagi, Shweta, Schutz, Frederic, Herr, Winship

“…We show here that, in HeLa cells, HCFC1 is observed bound to 5400 generally active CpG-island promoters. Examination of the DNA sequences underlying the HCFC1-binding sites revealed three sequence motifs associated with the binding of (1) ZNF143 and THAP11 (also known as Ronin), (2) GABP, and (3) YY1 sequence-specific transcription factors. …”
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GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells by Mendenhall, Eric M., Koche, Richard Patrick, Truong, Thanh, Zhou, Vicky W., Issac, Biju, Chi, Andrew S., Ku, Manching, Bernstein, Bradley E.

“…We then pinpointed a CpG island within this locus as both necessary and sufficient for PRC2 recruitment. …”
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Characterisation and localisation of fertilization independent endosperm and enhancer of zeste-like transcripts from oil palm (Elaeis guineensis Jacq.) by Ramachandran, Vasagi

“…The methylation levels in CpG island of each genes were detected by using MSRE-PCR and Southern analysis. …”
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PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells by Das, Partha Pratim, Hendrix, David A., Apostolou, Effie, Buchner, Alice H., Canver, Matthew C., Beyaz, Semir, Ljuboja, Damir, Kuintzle, Rachael, Kim, Woojin, Karnik, Rahul, Shao, Zhen, Xie, Huafeng, Xu, Jian, De Los Angeles, Alejandro, Zhang, Yingying, Choe, Junho, Jun, Don Leong Jia, Shen, Xiaohua, Gregory, Richard I., Daley, George Q., Meissner, Alexander, Kellis, Manolis, Hochedlinger, Konrad, Kim, Jonghwan, Orkin, Stuart H., Hendrix, David A.

“…Previously, we had identified a CpG island within the human DNMT3L promoter and first exon that showed loss of DNA methylation in cancer samples. …”
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Epigenetic silencing of CYP24 in the tumor microenvironment by Johnson, C.S., Chung, I., Trump, D.L.

“…In TDEC, which are sensitive to calcitriol, the CYP24 promoter is hypermethylated in two CpG island regions located at the 5'end; this hypermethylation may contribute to gene silencing of CYP24. …”
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The role of DNA methylation in directing the functional organization of the cancer epigenome by Lay, Fides D., Liu, Yaping, Kelly, Theresa K., Witt, Heather, Farnham, Peggy J., Jones, Peter A., Berman, Benjamin P.

“…DNA methylation abolished this phasing primarily at enhancers and CpG island (CGI) promoters, with little effect on insulators and non-CGI promoters. …”
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A unique regulatory phase of DNA methylation in the early mammalian embryo by Chan, Michelle Mei Wah, Regev, Aviv, Smith, Zachary D., Gu, Hongcang, Gnirke, Andreas, Meissner, Alexander, Mikkelsen, Tarjei Sigurd, 1978-

“…Surprisingly, the oocyte contributes a unique set of differentially methylated regions (DMRs)—including many CpG island promoters—that are maintained in the early embryo but are lost upon specification and absent from somatic cells. …”
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DNA methylation dynamics of the human preimplantation embryo by Smith, Zachary D., Chan, Michelle Mei Wah, Humm, Kathryn C., Karnik, Rahul, Mekhoubad, Shila, Regev, Aviv, Eggan, Kevin, Meissner, Alexander

“…Although most features share similar dynamics to those in mouse, maternally contributed methylation is divergently targeted to species-specific sets of CpG island promoters that extend beyond known imprint control regions. …”
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Epigenetic silencing of CYP24 in tumor-derived endothelial cells contributes to selective growth inhibition by calcitriol by Chung, I., Karpf, A.R., Muindi, J.R., Conroy, J.M., Nowak, N.J., Johnson, C.S., Trump, D.L.

“…We identified two putative CpG island regions located at the 5' end. Using methylation-specific PCR and bisulfite sequencing, we determined that these CpG islands were hypermethylated in TDEC but not in MDEC. …”
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Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome by Flynn, Ryan A., Almada, Albert Ernesto, Zamudio, Jesse Ray, Sharp, Phillip A.

“…Divergent transcription occurs at the majority of RNA polymerase II (RNAPII) promoters in mouse embryonic stem cells (mESCs), and this activity correlates with CpG islands. Here we report the characterization of upstream antisense transcription in regions encoding transcription start site associated RNAs (TSSa-RNAs) at four divergent CpG island promoters: Isg20l1, Tcea1, Txn1, and Sf3b1. …”
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A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect by Lopez-Serra, Paula, Marcilla, Miguel, Villanueva, Alberto, Ramos-Fernandez, Antonio, Palau, Anna, Wahi, Jessica E., Setien-Baranda, Fernando, Szczesna, Karolina, Moutinho, Catia, Martinez-Cardus, Anna, Heyn, Holger, Sandoval, Juan, Puertas, Sara, Vidal, August, Sanjuan, Xavier, Martinez-Balibrea, Eva, Viñals, Francesc, Perales, Jose C., Bramsem, Jesper B., Andersen, Claus L., Tabernero, Josep, McDermott, Ultan, Boxer, Matthew B., Albar, Juan Pablo, Esteller, Manel, Vander Heiden, Matthew G., Leal, Lucia, Orntoft, Torben F.

“…Here we demonstrate the presence of promoter CpG island hypermethylation-linked inactivation of DERL3 (Derlin-3), a key gene in the endoplasmic reticulum-associated protein degradation pathway, in human tumours. …”
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Proteogenomic characterization of human colon and rectal cancer by White, Forest M.

“…Proteomics identified five proteomic subtypes in the TCGA cohort, two of which overlapped with the TCGA ‘microsatellite instability/CpG island methylation phenotype’ transcriptomic subtype, but had distinct mutation, methylation and protein expression patterns associated with different clinical outcomes. …”
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Molecular characterization and methylation status of torque teno virus isolation among hepatitis patients in a public hospital in Pahang, Malaysia by Hazanuddin, Siti Nurzulaikha

“…Lastly, the selected TTV Malaysian isolate was further investigated for the methylation properties in the region consist of the highest CG percentage among a few CpG island by bisulfite sequencing and methylation-specific PCR. …”
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Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex by Naik, Roshan R., Sotnikov, Sergey V., Diepold, Rebekka P., Iurato, Stella, Markt, Patrick O., Bultmann, Andrea, Brehm, Nadine, Mattheus, Tobias, Lutz, Beat, Erhardt, Angelika, Binder, Elisabeth B., Schmidt, Ulrike, Holsboer, Florian, Landgraf, Rainer, Czibere, Ludwig

“…In addition, there was no difference in basal DNA methylation in the CpG Island that encompasses the HAB vs. LAB Tmem132d promoter region. …”
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Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer by Shen, H., Fridley, B.L., Song, H.L., Lawrenson, K., Cunningham, J.M., Ramus, S.J., Cicek, M.S., Tyrer, J., Stram, D., Larson, M.C., Kobel, M., Ziogas, A., Zheng, W., Yang, H.P., Wu, A.H., Wozniak, E.L., Woo, Y.L., Winterhoff, B., Wik, E., Whittemore, A.S., Wentzensen, N., Weber, R.P., Vitonis, A.F., Vincent, D., Vierkant, R.A., Vergote, I., Van Den Berg, D., Van Altena, A.M., Tworoger, S.S., Thompson, P.J., Tessier, D.C., Terry, K.L., Teo, S.H., Templeman, C., Stram, D.O., Southey, M.C., Sieh, W., Siddiqui, N., Shvetsov, Y.B., Shu, X.O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H.B., Rzepecka, I.K., Runnebaum, I.B., Rossing, M.A., Rodriguez-Rodriguez, L., Risch, H.A., Renner, S.P., Poole, E.M., Pike, M.C., Phelan, C.M., Pelttari, L.M., Pejovic, T., Paul, J., Orlow, I., Omar, S.Z., Olson, S.H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R.B., Narod, S.A., Nakanishi, T., Moysich, K.B., Monteiro, A.N.A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J.R., McGuire, V., Matsuo, K., Adenan, N.A.M., Massuger, L.F.A.G., Lurie, G., Lundvall, L., Lubinski, J., Lissowska, J., Levine, D.A., Leminen, A., Lee, A.W., Le, N.D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G.E., Kjaer, S.K., Kiemeney, L.A., Kelemen, L.E., Keeney, G.L., Karlan, B.Y., Karevan, R., Kalli, K.R., Kajiyama, H., Ji, B.T., Jensen, A., Jakubowska, A.

“…Unmethylated, expressed HNF1B, primarily present in clear cell tumours, coincides with a CpG island methylator phenotype affecting numerous other promoters throughout the genome. …”

Low methylation of matrix metalloproteinase 1 (MMP1) is associated with preterm labour in Malaysian mothers by Mohamad Zainal, Nurul Hayati, Mohamed Ismail, Nor Azlin, M. Mokhtar, Norfilza

“…Primers for MMP1 were located between -1226 and -1378 upstream from the transcription start site (TSS) that consisted five CpG islands. Preterm labour group had significantly lower methylated CpG islands with 39 out of total 75 (52%) compared to the term labour that has 49 out of 75 methylated CpG islands (65.33%) (t=0.694, p<0.05). …”