Showing 161 - 180 results of 190,930 for search '"DNA', query time: 0.69s Refine Results
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    Searching for DNA Lesions: Structural Evidence for Lower- and Higher-Affinity DNA Binding Conformations of Human Alkyladenine DNA Glycosylase by Setser, Jeremy W., Lingaraju, Gondichatnahalli M., Davis, C. Ainsley, Samson, Leona D., Drennan, Catherine L

    Published 2012
    “…To efficiently repair DNA, human alkyladenine DNA glycosylase (AAG) must search the million-fold excess of unmodified DNA bases to find a handful of DNA lesions. …”
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  7. 167

    Revealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetry by Zhang, Xinghua, Chen, Hu, Le, Shimin, Rouzina, Ioulia, Doyle, Patrick S., Yan, Jie

    Published 2013
    “…Double-stranded DNA (dsDNA) unconstrained by torsion undergoes an overstretching transition at about 65 pN, elongating the DNA to about 1.7-fold. …”
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    The inhibition of anti-DNA binding to DNA by nucleic acid binding polymers. by Nancy A Stearns, Jaewoo Lee, Kam W Leong, Bruce A Sullenger, David S Pisetsky

    Published 2012-01-01
    “…Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus (SLE) and can mediate disease pathogenesis by the formation of immune complexes. …”
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    DNA methylation patterns in cord blood DNA and body size in childhood. by Caroline L Relton, Alexandra Groom, Beate St Pourcain, Adrian E Sayers, Daniel C Swan, Nicholas D Embleton, Mark S Pearce, Susan M Ring, Kate Northstone, Jon H Tobias, Joseph Trakalo, Andy R Ness, Seif O Shaheen, George Davey Smith

    Published 2012-01-01
    “…The goal of this study was to investigate whether DNA methylation levels at birth are associated with body size later in childhood.A study design involving two birth cohorts was used to conduct transcription profiling followed by DNA methylation analysis in peripheral blood. …”
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  14. 174

    Temporary HMCES-DNA cross-link prevents permanent DNA damage by Penelope D. Ruiz, Agata Smogorzewska

    Published 2024-01-01
    “…HMCES, a recently discovered but ancient protein, covalently attaches to damaged single-stranded DNA and shields it from nucleases. Rua-Fernandez and colleagues now show that HMCES catalyzes its own recycling, permitting normal growth and non-mutagenic DNA repair.1…”
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    Structure of genomic DNA in chicken populations revealed by multilocus DNA probe by Valeriy P. Terletskiy, Valentina I. Tyshchenko

    Published 2023-03-01
    “…The aim of this work was to obtain new knowledge about the structure of genomic DNA of six chicken populations using multilocus analysis with a labeled molecular probe (GTG)5. …”
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  18. 178

    Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes by Stefano Stassi, Monica Marini, Marco Allione, Sergei Lopatin, Domenico Marson, Erik Laurini, Sabrina Pricl, Candido Fabrizio Pirri, Carlo Ricciardi, Enzo Di Fabrizio

    Published 2019-04-01
    “…Intercalating molecules can significantly change the conformation of DNA. Here, the authors fabricated resonators fully composed of DNA forming bundles between microfabricated pillars to study the vibration property of the DNA bundles with/without intercalant molecules.…”
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  19. 179

    DNA damage, demethylation and anticancer activity of DNA methyltransferase (DNMT) inhibitors by Angelo B. A. Laranjeira, Melinda G. Hollingshead, Dat Nguyen, Robert J. Kinders, James H. Doroshow, Sherry X. Yang

    Published 2023-04-01
    “…Abstract Role of DNA damage and demethylation on anticancer activity of DNA methyltransferase inhibitors (DNMTi) remains undefined. …”
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  20. 180

    Metagenomic DNA sequencing to quantify Mycobacterium tuberculosis DNA and diagnose tuberculosis by Adrienne Chang, Omary Mzava, Liz-Audrey Kounatse Djomnang, Joan Sesing Lenz, Philip Burnham, Peter Kaplinsky, Alfred Andama, John Connelly, Christine M. Bachman, Adithya Cattamanchi, Amy Steadman, Iwijn De Vlaminck

    Published 2022-10-01
    “…Using mathematical modeling and quantitative comparisons to matched qPCR data, we found that the burden of Mycobacterium tuberculosis DNA constitutes a very small fraction (0.04 or less) of the total abundance of DNA originating from mycobacteria in samples from TB endemic regions. …”
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