CDNA library from the Latex of Hevea brasiliensis by Wilaiwan Chotigeat, Sarapee Duangchu, Amornrat Phongdara

“…Other categories included, protein synthesis-related proteins (6.6%), chromatin and DNA metabolism(CDM 3.9%), energy metabolism (EM 3.4%), cellular transport (CT 3.2%), cell structure (CS 3.2%), signal transduction (ST2.2%), secondary metabolism (SM 1.7%), protein fate (PF 2.2%), and reproductive proteins (RP 0.7%).…”
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Differential gene expression analysis and cytological evidence reveal a sexual stage of an amoeba with multiparental cellular and nuclear fusion. by Yonas I Tekle, Fang Wang, Alireza Heidari, Alanna Johnson Stewart

“…Relative gene ontology (GO) category representations in unfused and fused cells revealed a functional skew of the fused transcriptome toward DNA metabolism, nucleus and ligases that are suggestive of a commitment to sexual development. …”
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Dual functions for the ssDNA-binding protein RPA in meiotic recombination. by Baolu Shi, Jiangyang Xue, Hao Yin, Rui Guo, Mengcheng Luo, Lan Ye, Qinghua Shi, Xiaoyan Huang, Mingxi Liu, Jiahao Sha, P Jeremy Wang

“…The replication protein A (RPA) complex, the predominant ssDNA-binding complex, is required for nearly all aspects of DNA metabolism, but its role in mammalian meiotic recombination remains unknown due to the embryonic lethality of RPA mutant mice. …”
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Vitamin Β12 and Folic Acid Effects on Polyamine Metabolism in Rat Liver by Bjelakovic Gordana, Pavlovic Dusica, Jevtovic Tatjana, Stojanovic Ivana, Sokolovic Dušan, Bjelakovic Goran B., Nikolic Jelenka, Basic Jelena

“…Metabolism of polyamines is associated with growth and differentiation of mammalian cells, spermine related to RNA and spermidine to DNA metabolism. Methyl-cobalamin, the coenzyme of methionine synthetase, catalyses the recycling of homocysteine to methionine using 5-methyltctrahydrofolate. …”
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DNA Double Strand Breaks and Chromosomal Translocations Induced by DNA Topoisomerase II by Fernando Gómez-Herreros, Fernando Gómez-Herreros

“…DNA topoisomerases are essential enzymes present in all cellular organisms with critical roles in DNA metabolism and that have been linked to the formation of deleterious DSBs for a long time. …”
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Anesthesia for bariatric surgery in patient with mitochondrial myopathy – case report by Carlos Eduardo Coimbra Melonio, Ciro Bezerra Vieira, Plínio C. Leal, Caio Marcio B. de Oliveira, Elizabeth T.N. Servín, Lyvia Maria Rodrigues de Sousa Gomes, Ed Carlos R. Moura

“…Mitochondrial Myopathy is a rare pathology caused by a defect in the mitochondrial DNA metabolism, leading to defects in the formation of adenosine triphosphate, in the Krebs citric acid cycle, fatty acid oxidation and oxidative phosphorylation. …”
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Iron–Sulfur Cluster Biogenesis as a Critical Target in Cancer by Michael S. Petronek, Douglas R. Spitz, Bryan G. Allen

“…Iron–sulfur (Fe–S) clusters are critical cofactors that aid in a wide variety of cellular functions (e.g., DNA metabolism and electron transport). In this article, we theorize that a differential need for Fe–S biogenesis in tumor versus non-malignant cells underlies the Fe-dependent cell growth demand of cancer cells to promote cell division and survival by promoting genomic stability via Fe–S containing DNA metabolic enzymes. …”
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Differential chromosome conformations as hallmarks of cellular identity revealed by mathematical polymer modeling. by Imen Lassadi, Alain Kamgoué, Isabelle Goiffon, Nicolas Tanguy-le-Gac, Kerstin Bystricky

“…Inherently dynamic, chromosomes adopt many different conformations in response to DNA metabolism. Models of chromosome organization in the yeast nucleus obtained from genome-wide chromosome conformation data or biophysical simulations provide important insights into the average behavior but fail to reveal features from dynamic or transient events that are only visible in a fraction of cells at any given moment. …”
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BRG1 Promotes chromatin remodeling around DNA damage sites by Wenjing Qi, Hongyu Chen, Chengwen Lu, Qingpan Bu, Xiaoguang Wang, Liping Han

“…Chromatin remodeling complexes play important roles in various DNA metabolism processes, including DNA damage repair. …”
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P1 Ref Endonuclease: A Molecular Mechanism for Phage-Enhanced Antibiotic Lethality. by Erin A Ronayne, Y C Serena Wan, Beth A Boudreau, Robert Landick, Michael M Cox

“…DNA binding by Ref interferes with normal DNA metabolism, and the nuclease activity of Ref enhances genome degradation. …”
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Genome maintenance and transcription integrity in ageing and disease by Stefanie eWolters, Björn eSchumacher, Björn eSchumacher

“…DNA damage interferes with DNA metabolism by blocking replication and transcription. …”
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Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease. by Bird, J, Jennert-Burston, K, Bachler, M, Mason, P, Lowe, J, Heo, S, Campisi, J, Faragher, R, Cox, L

“…WRN is a RecQ helicase with an associated exonuclease activity important in DNA metabolism, including DNA replication, repair and recombination. …”

DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda. by Monika Hlavová, Mária Čížková, Milada Vítová, Kateřina Bišová, Vilém Zachleder

“…The cells delayed S phase and underwent a permanent G2 phase block if DNA metabolism was affected prior to S phase; the G2 phase block imposed by zeocin was partially abolished by caffeine. …”
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3D structure prediction of replication factor C subunits (RFC) and their interactome in Arabidopsis thaliana by Mohamed Ragab Abdel Gawwad, Jasmin Sutkovic, Emina Zahirovic, et al.

“…RFC1 is identical to CDC44, a gene identified as a cell division cycle gene encoding a protein involved in DNA metabolism. Subcellular localization and interactions of each protein RFC protein subunit is determined. …”
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Extracellular DNA release by undomesticated Bacillus subtilis is regulated by early competence. by Olga Zafra, María Lamprecht-Grandío, Carolina González de Figueras, José Eduardo González-Pastor

“…Transposon insertions in genes related to quorum sensing and competence (oppA, oppF and comXP) and to DNA metabolism (mfd and topA) were impaired in eDNA release. …”
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Rtt105 regulates RPA function by configurationally stapling the flexible domains by Sahiti Kuppa, Jaigeeth Deveryshetty, Rahul Chadda, Jenna R. Mattice, Nilisha Pokhrel, Vikas Kaushik, Angela Patterson, Nalini Dhingra, Sushil Pangeni, Marisa K. Sadauskas, Sajad Shiekh, Hamza Balci, Taekjip Ha, Xiaolan Zhao, Brian Bothner, Edwin Antony

“…The single stranded DNA binding protein RPA coordinates DNA metabolism using multiple protein and DNA interaction domains. …”
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Hypomorphic PCNA mutation underlies a human DNA repair disorder. by Baple, E, Chambers, H, Cross, H, Fawcett, H, Nakazawa, Y, Chioza, B, Harlalka, G, Mansour, S, Sreekantan-Nair, A, Patton, M, Muggenthaler, M, Rich, P, Wagner, K, Coblentz, R, Stein, C, Last, J, Taylor, A, Jackson, A, Ogi, T, Lehmann, A, Green, C, Crosby, A

“…The p.Ser228Ile change also profoundly altered PCNA's interaction with Flap endonuclease 1 and DNA Ligase 1, DNA metabolism enzymes. Together, our findings detail a mutation of PCNA in humans associated with a neurodegenerative phenotype, displaying clinical and molecular features common to other DNA repair disorders, which we showed to be attributable to a hypomorphic amino acid alteration.…”

Recapitulation of Werner syndrome sensitivity to camptothecin by limited knockdown of the WRN helicase/exonuclease by Bird, J, Jennert-Burston, K, Bachler, M, Mason, P, Lowe, J, Heo, S, Campisi, J, Faragher, R, Cox, L

“…WRN is a RecQ helicase with an associated exonuclease activity important in DNA metabolism, including DNA replication, repair and recombination. …”

Replication fork blockage by transcription factor-DNA complexes in Escherichia coli. by Payne, B, van Knippenberg, I, Bell, H, Filipe, SR, Sherratt, D, McGlynn, P

“…We conclude that there is a trade-off between efficient genome duplication and other aspects of DNA metabolism such as transcriptional control, and that recombination enzymes, either directly or indirectly, provide the means to tolerate such conflicts.…”

Mgm101: A double-duty Rad52-like protein. by Rendeková, J, Ward, T, Šimoničová, L, Thomas, P, Nosek, J, Tomáška, Ľ, McHugh, P, Chovanec, M

“…Recent work has demonstrated a further role for Mgm101 in nuclear DNA metabolism, contributing to an S-phase specific DNA interstrand cross-link repair pathway that acts redundantly with a pathway controlled by Pso2 exonuclease. …”