Showing 1 - 20 results of 295 for search '"DNA metabolism"', query time: 7.42s Refine Results
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    POLDIP3: At the Crossroad of RNA and DNA Metabolism by Manrose Singh, Sufang Zhang, Alexis M. Perez, Ernest Y. C. Lee, Marietta Y. W. T. Lee, Dong Zhang

    Published 2022-10-01
    “…We then propose a unified model to illustrate how POLDIP3 plays such a versatile role at the crossroad of the RNA and DNA metabolism.…”
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    Article
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    DNA Metabolism in Balance: Rapid Loss of a RecA-Based Hyperrec Phenotype. by Irina V Bakhlanova, Alexandra V Dudkina, Elizabeth A Wood, Vladislav A Lanzov, Michael M Cox, Dmitry M Baitin

    Published 2016-01-01
    “…The results indicate that the toxicity of RecA D112R is due to its persistent binding to duplex genomic DNA, creating barriers for other processes in DNA metabolism. A substantial selective pressure is generated to suppress the resulting barrier to growth.…”
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    Unravelling How Single-Stranded DNA Binding Protein Coordinates DNA Metabolism Using Single-Molecule Approaches by Longfu Xu, Matthew T. J. Halma, Gijs J. L. Wuite

    Published 2023-02-01
    “…Single-stranded DNA-binding proteins (SSBs) play vital roles in DNA metabolism. Proteins of the SSB family exclusively and transiently bind to ssDNA, preventing the DNA double helix from re-annealing and maintaining genome integrity. …”
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    Article
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    Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design by Attila Tököli, Brigitta Bodnár, Ferenc Bogár, Gábor Paragi, Anasztázia Hetényi, Éva Bartus, Edit Wéber, Zsófia Hegedüs, Zoltán Szabó, Gábor Kecskeméti, Gerda Szakonyi, Tamás A. Martinek

    Published 2023-03-01
    “…Understanding the structural adaptation of the disordered SSB C-terminus (SSB-Ct) to DNA metabolizing enzymes (e.g., ExoI and RecO) is essential for designing high-affinity SSB mimetic inhibitors. …”
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    Article
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    DNA polymerases and diseases by Ramadan, K, Maga, G, Hübscher, U

    Published 2007
    “…In this chapter, we would like to highlight the possible connections between DNA polymerases, the main enzymes in DNA metabolism, and human diseases, also critically evaluating those cases where the experimental data are not fully convincing. …”
    Journal article