A molecular characterization of the meiotic initiation factor STRA8 in mice by Kojima, Mina L

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Studies of DNA repair and mutagenesis in Escherichia coli and Bacillus subtilis by Smith, Bradley Theodore

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Drug delivery strategies for platinum-based chemotherapy by Browning, R, Reardon, P, Parhizkar, M, Pedley, B, Edirisinghe, M, Knowles, J, Stride, E

“…The first member of the platinum based drug family, CDDP’s potent toxicity in disrupting DNA replication has led to its widespread use in multi-drug therapies, with particular benefit in patients with testicular cancers. …”

Early diagnosis of oesophageal cancer. by Bird-Lieberman, E, Fitzgerald, R

“…Inflammation leads to somatically inherited genetic mutations altering control of the cell cycle, DNA replication and apoptosis, which together result in autonomous and uncontrolled proliferation. …”

Regulated protein kinases and phosphatases in cell cycle decisions by Novak, B, Kapuy, O, Domingo-Sananes, MR, Tyson, J

“…These general principles are applied to cell cycle transitions, with special emphasis on the roles of regulated phosphatases in orchestrating progression from one phase to the next of the DNA replication-division cycle. © 2010 Elsevier Ltd.…”

Regulated protein kinases and phosphatases in cell cycle decisions. by Novak, B, Kapuy, O, Domingo-Sananes, MR, Tyson, J

“…These general principles are applied to cell cycle transitions, with special emphasis on the roles of regulated phosphatases in orchestrating progression from one phase to the next of the DNA replication-division cycle.…”

ADP-ribosylation: new facets of an ancient modification by Palazzo, L, Mikoč, A, Ahel, I

“…Amongst these, ADP-ribosylation is of emerging interest because of its ability to modify different macromolecules in the cells, and its association with many key biological processes, such as DNA-damage repair, DNA replication, transcription, cell division, signal transduction, stress and infection responses, microbial pathogenicity and aging. …”

Mitochondrial genome repositioning during the differentiation of the African trypanosome between life cycle forms is microtubule mediated. by Matthews, K, Sherwin, T, Gull, K

“…We have found that repositioning occurs simultaneously with the DNA replication phase of the cell cycle of the differentiating parasite. …”

The DNA helicase Pfh1 promotes fork merging at replication termination sites to ensure genome stability. by Steinacher, R, Osman, F, Dalgaard, J, Lorenz, A, Whitby, M

“…Bidirectionally moving DNA replication forks merge at termination sites composed of accidental or programmed DNA-protein barriers. …”

The emerging role of Mule and ARF in the regulation of base excision repair. by Khoronenkova, S, Dianov, G

“…In this review, we will summarise the major properties of Mule and ARF and their roles in the coordination of DNA repair and DNA replication.…”

The Fml1-MHF complex suppresses inter-fork strand annealing in fission yeast by Wong, I, Neo, J, Oehler, J, Schafhauser, S, Osman, F, Carr, S, Whitby, M

“…Previously we reported that a process called inter-fork strand annealing (IFSA) causes genomic deletions during the termination of DNA replication when an active replication fork converges on a collapsed fork (Morrow et al., 2017). …”

The replication fork trap and termination of chromosome replication. by Duggin, I, Wake, R, Bell, S, Hill, T

“…Bacteria that have a circular chromosome with a bidirectional DNA replication origin are thought to utilize a 'replication fork trap' to control termination of replication. …”

Decatenation of DNA circles by FtsK-dependent Xer site-specific recombination. by Ip, S, Bregu, M, Barre, F, Sherratt, D

“…DNA replication results in interlinked (catenated) sister duplex molecules as a consequence of the intertwined helices that comprise duplex DNA. …”

A novel checkpoint mechanism regulating the G1/S transition. by Tvegård, T, Soltani, H, Skjølberg, H, Krohn, M, Nilssen, E, Kearsey, S, Grallert, B, Boye, E

“…However, the G1-specific synthesis of factors required for DNA replication was not reduced by ultraviolet radiation. …”

The emerging role of Mule and ARF in the regulation of base excision repair by Khoronenkova, S, Dianov, G

“…In this review, we will summarise the major properties of Mule and ARF and their roles in the coordination of DNA repair and DNA replication. © 2011 Federation of European Biochemical Societies. …”

Mammalian base excision repair: the forgotten archangel. by Dianov, G, Hübscher, U

“…The major goal of this review is to critically examine controversial and newly emerging questions about mammalian BER pathways, mechanisms regulating BER capacity, BER responses to DNA damage and their links to checkpoint control of DNA replication.…”

Visualization of replication sites in unfixed human cells. by Hassan, A, Cook, P

“…Sites of DNA replication in nuclei are focally concentrated, suggesting that an underlying structure organizes the activity of many polymerases. …”

System-level feedbacks control cell cycle progression. by Kapuy, O, He, E, López-Avilés, S, Uhlmann, F, Tyson, J, Novák, B

“…Oscillations of Cdk1/CycB activity between low and high levels during the cycle trigger DNA replication and mitosis in the correct order. Based on computational modeling, we proposed that the low and the high kinase activity states are alternative stable steady states of a bistable Cdk-control system. …”

The DNA-remodelling activity of DnaD is the sum of oligomerization and DNA-binding activities on separate domains. by Carneiro, M, Zhang, W, Ioannou, C, Scott, D, Allen, S, Roberts, C, Soultanas, P

“…The Bacillus subtilis DnaD protein is an essential protein that has been implicated in the primosomal step of DNA replication, and recently in global DNA remodelling. …”

Structure of the heterodimeric core primase. by Lao-Sirieix, S, Nookala, R, Roversi, P, Bell, S, Pellegrini, L

“…Primases are DNA-dependent RNA polymerases that synthesize the oligoribonucleotide primers essential to DNA replication. In archaeal and eukaryotic organisms, the core primase is a heterodimeric enzyme composed of a small and a large subunit. …”