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The molecular biology of DNA replication in the archaeon Sulfolobus solfataricus
Published 2012“…<p>DNA replication is essential for the propagation of all living organisms. …”
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Asymmetry of DNA replication fork progression in Werner's syndrome.
Published 2002“…We propose that WRN acts in normal DNA replication to prevent collapse of replication forks or to resolve DNA junctions at stalled replication forks, and that loss of this capacity may be a contributory factor in premature aging.…”
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DNA replication with an unnaturally large replicon in Saccharomyces cerevisiae
Published 2019“…<p>Eukaryotic cells co-regulate DNA replication and the cell cycle, ensuring a single round of replication occurs during each cell cycle. …”
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Multiple mechanisms for overcoming lethal over‐initiation of DNA replication
Published 2022“…DNA replication is highly regulated and primarily controlled at the step of initiation. …”
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Cell cycle regulation of complex formation at origins of DNA replications
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Nutritional Control of Elongation of DNA Replication by (p)ppGpp
Published 2014“…DNA replication is highly regulated in most organisms. …”
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Adenovirus cores can function as templates in in vitro DNA replication.
Published 1983“…Using both cores and DNA-protein complexes as templates, it was also demonstrated that novobiocin, an inhibitor of DNA gyrase, inhibited in vitro DNA replication by preventing formation of the initiation complex.…”
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Enigmatic variations: divergent modes of regulating eukaryotic DNA replication.
Published 2003“…Proteins involved in DNA replication are conserved from yeast to mammals, suggesting that the mechanism was established at an early stage of eukaryotic evolution. …”
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Cohesin can remain associated with chromosomes during DNA replication
Published 2017“…To ensure disjunction to opposite poles during anaphase, sister chromatids must be held together following DNA replication. This is mediated by cohesin, which is thought to entrap sister DNAs inside a tripartite ring composed of its Smc and kleisin (Scc1) subunits. …”
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Sister chromatid cohesion establishment during DNA replication termination
Published 2024“…While the converging replisomes are removed during DNA replication termination, cohesin remains on nascent DNA and provides cohesion. …”
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The configuration of DNA replication sites within the Trypanosoma brucei kinetoplast.
Published 1994“…These studies provide a new method for observing kinetoplast DNA (kDNA) replication patterns at high resolution. The techniques reveal that initially the pattern of replicated DNA is antipodal and can be detected both on isolated complexes and in replicating kDNA in vivo. …”
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Stoichiometry and architecture of active DNA replication machinery in Escherichia coli.
Published 2010Journal article -
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Extra-chromosomal elements and the evolution of cellular DNA replication machineries.
Published 2008“…DNA replication is fundamental to the propagation of cellular life. …”
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The importance of DNA replication termination and the MHF complex to genome stability
Published 2015Thesis -
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The role of hypoxia-induced RRM2B in DNA replication
Published 2016“…Severe levels of hypoxia induce DNA replication stress characterised by an increased number of stalled replication forks and significantly reduced replication rates, which occurs in the absence of DNA damage. …”
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36
Mechanisms preventing DNA replication between Meiosis I and Meiosis II
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Separation of DNA Replication from the Assembly of Break-Competent Meiotic Chromosomes
Published 2012“…Thus, although pre-meiotic DNA replication and meiotic chromosome axis formation occur concurrently, they are not strictly coupled. …”
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In vivo single-molecule imaging of bacterial DNA replication, transcription, and repair.
Published 2014Journal article -
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Roles of BRCA1 and BRCA2 in DNA replication and genome stability
Published 2017“…This provides an important rationale for further exploring the roles of BRCA1 and BRCA2 in DNA replication and genome stability.</p> <p>G-quadruplexes, alternative DNA structures formed by guanine-rich single- stranded DNA, represent natural replication fork barriers. …”
Thesis