Localization studies of sister-chromatid cohesion proteins MEI-S332 and RAD21 in Drosophila מאת Lee, Janice Ying, 1974-

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The role of retinoic acid in germ cell development in embryonic mouse gonads מאת Koubová, Jana C

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Autonomous Plasmid-like Replication of a Conjugative Transposon מאת Babic, Ana, Lee, Catherine Ann, Grossman, Alan Davis

"...Transfer of ICEBs1 from the donor required PcrA, but did not require replication, indicating that PcrA, and not DNA replication, facilitates unwinding of ICEBs1 DNA for horizontal transfer. ..."
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Computational analysis of core promoters in the Drosophilagenome מאת Ohler, Uwe, Liao, Guo-chun, Niemann, Heinrich, Rubin, Gerald M

"...Among the prevalent motifs is the DNA-replication-related element DRE, recently shown to be part of the recognition site for the TBP-related factor TRF2. ..."
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Analysis of a Drosophila amplicon in follicle cells highlights the diversity of metazoan replication origins מאת Kim, Jane C., Orr-Weaver, Terry

"...Drosophila amplicon in follicle cells (DAFCs), genomic regions that undergo repeated rounds of DNA replication to increase DNA copy number, serve as powerful in vivo model replicons. ..."
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The oocyte-to-embryo transition : regulation of oocyte maturation and egg activation in Drosophila מאת Weingarten, Lisa Suzanne

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A Cell-Type-Specific Protein-Protein Interaction Modulates Transcriptional Activity of a Master Regulator in Caulobacter crescentus מאת Gora, Kasia G., Tsokos, Christos G., Chen, Y. Erin, Srinivasan, Balaji S., Perchuk, Barrett, Laub, Michael T

"...CtrA is abundant throughout the cell cycle except immediately prior to DNA replication. However, the expression of CtrA-activated genes is generally restricted to S phase. ..."
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High-Resolution Mapping of the Spatial Organization of a Bacterial Chromosome מאת Imakaev, Maksim Viktorovich, Le, Tung, Mirny, Leonid A, Laub, Michael T

"...These domains are stable throughout the cell cycle and are reestablished concomitantly with DNA replication. We provide evidence that domain boundaries are established by highly expressed genes and the formation of plectoneme-free regions, whereas the histone-like protein HU and SMC (structural maintenance of chromosomes) promote short-range compaction and the colinearity of chromosomal arms, respectively. ..."
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A conserved MCM single-stranded DNA binding element is essential for replication initiation מאת Froelich, Clifford A., Kang, Sukhyun, Epling, Leslie B., Enemark, Eric J., Bell, Stephen P

"...The ring-shaped MCM helicase is essential to all phases of DNA replication. The complex loads at replication origins as an inactive double-hexamer encircling duplex DNA. ..."
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The SMC Complex MukBEF Recruits Topoisomerase IV to the Origin of Replication Region in Live Escherichia coli מאת Nicolas, Emilien, Upton, Amy L., Uphoff, Stephan, Henry, Olivia, Badrinarayanan, Anjana, Sherratt, David

"...Using live-cell quantitative imaging, we show that MukBEF directs TopoIV to ori, with fluorescent fusions of ParC and ParE both forming cellular foci that colocalize with those formed by MukBEF throughout the cell cycle and in cells unable to initiate DNA replication. Removal of MukBEF leads to loss of fluorescent ParC/ParE foci. ..."
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Conserved electron donor complex Dre2-Tah18 is required for ribonucleotide reductase metallocofactor assembly and DNA synthesis מאת Zhang, Yan, Li, Haoran, Zhang, Caiguo, An, Xiuxiang, Liu, Lili, Stubbe, JoAnne, Huang, Mingxia

"...Eukaryotic ribonucleotide reductases (RNRs) require a diferric-tyrosyl radical (Fe[III over 2]-Y•) cofactor to produce deoxynucleotides essential for DNA replication and repair. This metallocofactor is an important target of RNR-based therapeutics, although mechanisms of in vivo cofactor assembly, inactivation, and reactivation are poorly understood. ..."
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A DNA Damage-Induced, SOS-Independent Checkpoint Regulates Cell Division in Caulobacter crescentus מאת Modell, Joshua W., Kambara, Tracy K., Perchuk, Barrett, Laub, Michael T

"...Cells must coordinate DNA replication with cell division, especially during episodes of DNA damage. ..."
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Redox-Linked Changes to the Hydrogen-Bonding Network of Ribonucleotide Reductase β2 מאת Offenbacher, Adam R., Minnihan, Ellen Catherine, Stubbe, JoAnne, Barry, Bridgette A.

"...Ribonucleotide reductase (RNR) catalyzes conversion of nucleoside diphosphates (NDPs) to 2′-deoxynucleotides, a critical step in DNA replication and repair in all organisms. Class-Ia RNRs, found in aerobic bacteria and all eukaryotes, are a complex of two subunits: α2 and β2. ..."
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Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast מאת Sheltzer, Jason Meyer, Blank, Heidi Marie, Meehl, Colleen M., Amon, Angelika B

"...We show that Rad52-GFP foci form during S phase, consistent with the observation that DNA replication initiation and elongation are impaired in some aneuploid yeast strains. ..."
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Direct quantification of the translocation activities of Saccharomyces cerevisiae Pif1 helicase מאת Lu, Chen, Le, Shimin, Chen, Jin, Byrd, Alicia K., Rhodes, Daniela, Raney, Kevin D., Yan, Jie

"...Saccharomyces cerevisiae Pif1 (ScPif1) is known as an ATP-dependent DNA helicase that plays critical roles in a number of important biological processes such as DNA replication, telomere maintenance and genome stability maintenance. ..."
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Manipulation of G-quadruplex nanostructures using sequence engineering and chemical modifications: towards development of functional G-quadruplex scaffolds מאת Singh, Abhishek

"...These structures are shown to exist inside the cells and play important roles in various crucial processes like gene expression, DNA replication, transcription and translation. Synthetic G4s are shown to have different functional applications in therapeutics and nanotechnology. ..."
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Unravelling gene regulation in the epidermis during differentiation מאת Anisa Banu Abdul Rahim

"...Polyamines are small polycationic molecules that are essential for many cellular processes including DNA replication, RNA modification and protein synthesis. ..."
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Expression of S-phase cyclins affects sensitivity to DNA damage response modulators מאת Jung, H

"...<p>DNA replication stress triggers an intra-S phase checkpoint that is dependent on Ataxia- Telangiectasia and Rad3 related (ATR) kinase signalling. ..."

Microsatellite instability in early onset and familial colorectal cancer. מאת Brassett, C, Joyce, J, Froggatt, N, Williams, G, Furniss, D, Walsh, S, Miller, R, Evans, D, Maher, E

"...The majority of HNPCC families have germline mutations in mismatch repair (MMR) genes, such as MSH2 or MLH1, so that HNPCC cancers characteristically exhibit DNA replication errors (RERs) at microsatellite loci. ..."

Roles for NUCKS1 in cell cycle progression and the DNA damage response מאת Hume, S

"...NUCKS1 is a transcription factor implicated in cell cycle progression, DNA replication, and tumourigenesis. However, detailed mechanistic studies explaining how NUCKS1 controls these functions have not been performed. ..."