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621
Transcriptome profile of 28-4+ intraepithelial lymphocyte natural killer cells of chicken infected by virulent infectious bursal disease virus
Published 2019“…The DE genes at 1 dpi mainly involved in DNA replication, cell cycle, apoptosis whereas the DE genes at 3 dpi involved in inflammation, antiviral response and interferon stimulation. …”
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Thesis -
622
An endogenous dAMP ligand in
Published 2018“…The high fidelity of DNA replication and repair is attributable, in part, to the allosteric regulation of ribonucleotide reductases (RNRs) that maintains proper deoxynucleotide pool sizes and ratios in vivo. …”
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623
Studies of bacterial homeostasis Sinorhizobium meliloti and Escherichia coli
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Thesis -
624
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625
Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection
Published 2023“…In addition to HR repair, the role of RAD51C in DNA replication is emerging when replication forks are transiently or irreversibly stalled. …”
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Journal Article -
626
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627
TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
Published 2025“…Mechanistically, the autophagy receptor TEX264 acts as a TOP1cc sensor at DNA replication forks, triggering TOP1cc processing by the p97 ATPase and mediating the delivery of TOP1cc to lysosomes in an MRE11-nuclease- and ATR-kinase-dependent manner. …”
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Journal Article -
628
Structural studies of the RPFF protein involved in Quorum Sensing and the IGHMBP2 protein involved in Spinal Muscular Atrophy with Respiratory Distress type 1
Published 2012“…Although several studies have pointed out Ighmbp2 involvement in DNA replication, transcription, pre-mRNA splicing, and RNA metabolism, its exact role remains elusive. …”
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Thesis -
629
Structural investigation of the ubiquitylation of nucleosome core particles by the E3 ligase BRCA1/BARD1
Published 2019“…Results over the last two decades have provided evidence that histone post-translational modifications (e.g., acetylation, methylation, and ubiquitylation) play a vital role in regulating numerous processes within the eukaryotic cell, such as transcriptional regulation, DNA replication, and repair, leading to genomic instability and tumor progression. …”
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Thesis -
630
Antimicrobial activities of Cynodon dactylon (L.) Pers. (Bermuda Grass) from Kota Kinabalu, Sabah
Published 2014“…Luminometric assessment based on ATP quantification however suggested some bacterial pathogens were dead due to other metabolic factors such as inhibition or interference with proteins synthesis, DNA replication, metabolic pathways etc. C. dactylon possesses great potential in combating both human and plant microbial pathogens and have bright future to be further investigated for supplement, alternative medications, or as a biological control agent in combating crop pathogen.…”
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Thesis -
631
Effect of combination therapy of ruthenium polypyridyl complex, [Ru(dppz)2(PIP)]2+ and parp inhibitors against several cancer cell lines
Published 2020“…The RPC, [Ru(dppz)2(PIP)]2+ or RuPIP where dppz = dipyrido[3,2-a:2’,3’-c]phenazine and PIP = 2-(pheny)- imidazo[4,5-f][1,10]phenantroline has demonstrated anticancer properties where it was shown to stall DNA replication fork progression resulting in the initiation of DNA damage response (DDR) signaling which further lead to the inhibition of cell proliferation through G1/S-mediated cell cycle arrest. …”
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Thesis -
632
Profiling dynamic chromatome reveals HP1BP3 as a key regulator of cell cycle and hypoxia cancer progression
Published 2014“…Data mining suggested that identified proteins were involved in chromatin-dependent events including transcriptional regulation, chromatin re-organization, and DNA replication and repair, while the quantitative data of differential released chromatin-associated proteins by partial nuclease digestion revealed the temporal interactions of these proteins with euchromatin and heterochromatin during interphase progression and different hypoxia stress conditions. …”
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Thesis -
633
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634
Environmental characterization and metagenomics analysis of biotic and abiotic factors in North Selangor Peat Swamp Forest, Malaysia
Published 2020“…The functional biomarkers detected in DS samples were connected to synthesis of proteins and amino acid related enzymes such as DNA replication, translation factors, RNA polymerase and aminoacyl_tRNAbiosynthesis were observed. …”
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Thesis -
635
Conserved imprinting associated with unique epigenetic signatures in the Arabidopsis genus
Published 2017“…Methylation within gene bodies is usually restricted to the CG context, which is maintained after DNA replication by the maintenance methyltransferase MET1. …”
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Article -
636
The two Escherichia coli chromosome arms locate to separate cell halves.
Published 2006“…DNA replication divides the circular Escherichia coli chromosome into equal arms (replichores). …”
Journal article -
637
EFFECTOF HIRA PROTEINONTRANSCRIPTIONALREGULATIONSOF GENESIN VERTEBRATECELLS
Published 2008“…ABSTRACT For better understanding of DNA replicating-coupled chromatin assembly and transcription regulation in eukaryotes, we studied biochemical and genetic analysis of nuclear-related proteins from chicken DT40 cell lines. …”
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638
Measurement of replication structures at the nanometer scale using super-resolution light microscopy.
Published 2010“…DNA replication, similar to other cellular processes, occurs within dynamic macromolecular structures. …”
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639
Measurement of replication structures at the nanometer scale using super-resolution light microscopy.
Published 2010“…DNA replication, similar to other cellular processes, occurs within dynamic macromolecular structures. …”
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640
Defects in maintenance of mitochondrial DNA are associated with intramitochondrial nucleotide imbalances
Published 2007“…Most are associated with defects in genes involved in mitochondrial deoxynucleotide metabolism or utilization, such as mutations in thymidine kinase 2 (TK2) as well as the mtDNA replicative helicase, Twinkle and gamma polymerase (POLG). …”
Journal article