Head to head comparison of short-term treatment with the NAD+ precursor nicotinamide mononucleotide (NMN) and six weeks of exercise in obese female mice by Golam Mezbah Uddin, Neil A Youngson, David A Sinclair, David A Sinclair, Margaret J Morris

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Can artificial intelligence identify effective COVID‐19 therapies? by Michael B Schultz, Daniel Vera, David A Sinclair

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MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. by Oliver Medvedik, Dudley W Lamming, Keyman D Kim, David A Sinclair

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Correction: nicotinamide impairs entry into and exit from meiosis I in mouse oocytes. by Angelique Riepsamen, Lindsay Wu, Laurin Lau, Dave Listijono, William Ledger, David A Sinclair, Hayden Homer

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Novel feature selection methods for construction of accurate epigenetic clocks. by Adam Li, Amber Mueller, Brad English, Anthony Arena, Daniel Vera, Alice E Kane, David A Sinclair

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Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers by Golam M. Uddin, Neil A. Youngson, Sabiha S. Chowdhury, Christopher Hagan, David A. Sinclair, Margaret J. Morris

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The Sirt1 activator SRT3025 expands hematopoietic stem and progenitor cells and improves hematopoiesis in Fanconi anemia mice by Qing-Shuo Zhang, Matthew Deater, Kathryn Schubert, Laura Marquez-Loza, Carl Pelz, David A. Sinclair, Markus Grompe

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The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function by João S. Teodoro, João A. Amorim, Ivo F. Machado, Ana C. Castela, Clemens Steegborn, David A. Sinclair, Anabela P. Rolo, Carlos M. Palmeira

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Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung by Pierre Montay-Gruel, Yafeng Zhu, Benoit Petit, Ron Leavitt, Mike Warn, Erich Giedzinski, Jonathan Ollivier, David A. Sinclair, Marie-Catherine Vozenin, Charles L. Limoli

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Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila by Justin A Bosch, Berrak Ugur, Israel Pichardo-Casas, Jordan Rabasco, Felipe Escobedo, Zhongyuan Zuo, Ben Brown, Susan Celniker, David A Sinclair, Hugo J Bellen, Norbert Perrimon

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Aging-like Phenotype and Defective Lineage Specification in SIRT1-Deleted Hematopoietic Stem and Progenitor Cells by Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, Brigitte Izac, Rebeca Dieguez-Gonzalez, Gaetan Barbet, Michael Donovan, Carlo Brugnara, Julie M. Blander, David A. Sinclair, Saghi Ghaffari

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Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty by Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair

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NMN Supplementation Rescues Fertility and Bone Strength in Chemotherapy-Treated Mice by Maria B. MARINOVA, Wing-Hong Jonathan HO, Michael J. BERTOLDO, Vedran LOVRIC, Kaisa SELESNIEMI, William R. WALSH, David A. SINCLAIR, Kirsty WALTERS, Robert B. GILCHRIST, Lindsay E. WU

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Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy. by Shaday Michan, Aimee M Juan, Christian G Hurst, Zhenghao Cui, Lucy P Evans, Colman J Hatton, Dorothy T Pei, Meihua Ju, David A Sinclair, Lois E H Smith, Jing Chen

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The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth. by Ron Firestein, Gil Blander, Shaday Michan, Philipp Oberdoerffer, Shuji Ogino, Jennifer Campbell, Anupama Bhimavarapu, Sandra Luikenhuis, Rafael de Cabo, Charles Fuchs, William C Hahn, Leonard P Guarente, David A Sinclair

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Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice by Shanlin Ke, Sarah J. Mitchell, Michael R. MacArthur, Alice E. Kane, David A. Sinclair, Emily M. Venable, Katia S. Chadaideh, Rachel N. Carmody, Francine Grodstein, James R. Mitchell, Yang-Yu Liu

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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mic... by Stefano Tarantini, Marta Noa Valcarcel-Ares, Peter Toth, Andriy Yabluchanskiy, Zsuzsanna Tucsek, Tamas Kiss, Peter Hertelendy, Michael Kinter, Praveen Ballabh, Zoltán Süle, Eszter Farkas, Joseph A. Baur, David A. Sinclair, Anna Csiszar, Zoltan Ungvari

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Quantitative proteomic analysis of extracellular vesicle subgroups isolated by an optimized method combining polymer‐based precipitation and size exclusion chromatography by Juan A. Martínez‐Greene, Karina Hernández‐Ortega, Ricardo Quiroz‐Baez, Osbaldo Resendis‐Antonio, Israel Pichardo‐Casas, David A. Sinclair, Bogdan Budnik, Alfredo Hidalgo‐Miranda, Eileen Uribe‐Querol, María del Pilar Ramos‐Godínez, Eduardo Martínez‐Martínez

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Comparing the Effects of Low-Protein and High-Carbohydrate Diets and Caloric Restriction on Brain Aging in Mice by Devin Wahl, Samantha M. Solon-Biet, Qiao-Ping Wang, Jibran A. Wali, Tamara Pulpitel, Ximonie Clark, David Raubenheimer, Alistair M. Senior, David A. Sinclair, Gregory J. Cooney, Rafael de Cabo, Victoria C. Cogger, Stephen J. Simpson, David G. Le Couteur

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Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload by Angela H. Guo, Rachael Baliira, Mary E. Skinner, Surinder Kumar, Anthony Andren, Li Zhang, Robert S. Goldsmith, Shaday Michan, Norma J. Davis, Merissa W. Maccani, Sharlene M. Day, David A. Sinclair, Matthew J. Brody, Costas A. Lyssiotis, Adam B. Stein, David B. Lombard

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