TOR Signaling and Rapamycin Influence Longevity by Regulating SKN-1/Nrf and DAF-16/FoxO by Robida-Stubbs, Stacey, Glover-Cutter, Kira, Lamming, Dudley W., Mizunuma, Masaki, Narasimhan, Sri Devi, Neumann-Haefelin, Elke, Sabatini, David M., Blackwell, T. Keith, Lamming, Dudley W., Sabatini, David

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Improving femtosecond laser pulse delivery through a hollow core photonic crystal fiber for temporally focused two-photon endomicroscopy by Choi, Heejin, So, Peter T. C.

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A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB by Settembre, Carmine, Zoncu, Roberto, Medina, Diego L., Vetrini, Francesco, Erdin, Serkan, Erdin, SerpilUckac, Huynh, Tuong, Ferron, Mathieu, Karsenty, Gerard, Vellard, Michel C., Facchinetti, Valeria, Ballabio, Andrea, Ballabio, Andrea, Sabatini, David

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A Diverse Array of Cancer-Associated MTOR Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity by Grabiner, Brian C., Nardi, Valentina, Birsoy, Kivanc, Possemato, Richard, Shen, Kuang, Sinha, Sumi, Jordan, Alexander, Beck, Andrew H., Sabatini, David

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Three-dimensional image cytometer based on widefield structured light microscopy and high-speed remote depth scanning by Choi, Heejin, Wadduwage, Dushan N., Tu, Ting Yuan, Matsudaira, Paul T., So, Peter T. C.

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A matrisome RNA signature from early-pregnancy mouse mammary fibroblasts predicts distant metastasis-free breast cancer survival in humans by Ayman M. Ibrahim, Alan Bilsland, Steffen Rickelt, Joanna S. Morris, Torsten Stein

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LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects by Hsin-Wei Liao, Christopher Garris, Christina Pfirschke, Steffen Rickelt, Sean Arlauckas, Marie Siwicki, Rainer H. Kohler, Ralph Weissleder, Vibeke Sundvold-Gjerstad, Baldur Sveinbjørnsson, Øystein Rekdal, Mikael J. Pittet

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Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis by Stefan Christen, Doriane Lorendeau, Roberta Schmieder, Dorien Broekaert, Kristine Metzger, Koen Veys, Ilaria Elia, Joerg Martin Buescher, Martin Franz Orth, Shawn Michael Davidson, Thomas Georg Philipp Grünewald, Katrien De Bock, Sarah-Maria Fendt

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Positioning SUMO as an immunological facilitator of oncolytic viruses for high-grade glioma by Paramesh V. Karandikar, Paramesh V. Karandikar, Lyle Suh, Jakob V. E. Gerstl, Sarah E. Blitz, Qing Rui Qu, Sae-Yeon Won, Florian A. Gessler, Omar Arnaout, Timothy R. Smith, Pier Paolo Peruzzi, Wei Yang, Gregory K. Friedman, Joshua D. Bernstock, Joshua D. Bernstock

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Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation by Zhengjian Zhang, Zarko Boskovic, Mahmud M Hussain, Wenxin Hu, Carla Inouye, Han-Je Kim, A Katherine Abole, Mary K Doud, Timothy A Lewis, Angela N Koehler, Stuart L Schreiber, Robert Tjian

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Rb interactome data and its modulations during cell cycle progression in HEK 293 cells by Shweta Duggal, Noor Jailkhani, Mukul Kumar Midha, Kanury V.S. Rao, Ajay Kumar

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Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons by Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W., Orlando, David A., Feldman, Danielle A., Bateup, Helen S., Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A., Sur, Mriganka, Young, Richard A., Jaenisch, Rudolf, Loven, Jakob, Vander Heiden, Matthew G., Feldman, Danielle A., Young, Richard A., Lewis, Caroline, Kwok, Show Ming

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Selective Mitogen Activated Protein Kinase Activity Sensors through the Application of Directionally Programmable D Domain Motifs by Peterson, Laura B, Yaffe, Michael B, Imperiali, Barbara

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Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors by Scherz-Shouval, R., Galie, P. A., Whitesell, L., Chen, C. S., Bagley, Alexander F, Zhang, Angela Q., Wyckoff, Jeffrey, Lindquist, Susan, Bhatia, Sangeeta N

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Beyond antigens and adjuvants: formulating future vaccines by Moyer, Tyson, Zmolek, Andrew Charles, Irvine, Darrell J

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Salt Effect Accelerates Site-Selective Cysteine Bioconjugation by Dai, Peng, Zhang, Chi, Welborn, Matthew Gregory, Shepherd, James J, Zhu, Tianyu, Van Voorhis, Troy, Pentelute, Bradley L.

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Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics by Kauffman, Kevin John, Xing, Yiping, Shaw, Taylor E., Mir, Faryal, Dlott, Chloe C., Langer, Robert S, Anderson, Daniel Griffith, Wang, Eric T, Dahlman, James E.

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Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles by Bekdemir, Ahmet, Watson, Nicki, Ingram, Jessica, Stellacci, Francesco R., Yang, Yu-Sang Sabrina, Moynihan, Kelly Dare, Dichwalkar, Tanmay M, Noh, Michelle M., Melo, Mariane Bandeira, Suh, Heikyung, Ploegh, Hidde, Irvine, Darrell J

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Functional Delivery of siRNA in Mice Using Dendriworms by Agrawal, Amit, Min, Dal-Hee, Singh, Neetu, Zhu, Haihao, Birjiniuk, Alona, Harris, Todd J., Xing, Deyin, Woolfenden, Stephen D., Sharp, Phillip A., Charest, Alain, von Maltzhan, Geoffrey, Bhatia, Sangeeta N

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mTORC1 in the Paneth cell niche couples intestinal stem cell function to calorie intake by Katajisto, Pekka, Lamming, Dudley W., Gultekin, Yetis, Bauer-Rowe, Khristian E., Sengupta, Shomit, Birsoy, Kivanc, Dursun, Abdulmetin, Yilmaz, V. Onur, Selig, Martin, Nielson, G. Petur, Mino-Kenudson, Mari, Zuckerberg, Lawrence, Bahn, Atul K., Deshpande, Vikram, Yilmaz, Omer, Sabatini, David

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