In vitro and in vivo antiviral effect of Fufang Yinhua Jiedu granules (FFYH) combined with oseltamivir against influenza A virus by Zhihui Zheng, Yuqian Zhang, Ming Li, Wenlei Wang, Hailin Wei, Qin Su, Ronghua Wang, Weiqing Shi, Lei Wang, Jianxiong Wu, Shuheng He, Xiaoquan Wang, Pinghu Zhang

“…In addition, virus titers in lung tissue and lung index were markedly reduced on day 6 post-infection by combination therapy of oseltamivir combined with FFYH at 0.25 and 0.5 g/kg/d. …”
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Oviductal extracellular matrix hydrogels enhance in vitro culture of rabbit embryos and reduce deficiencies during assisted reproductive technologies by Emilio Francés-Herrero, Laura Lorenzo-Rebenaque, Cristina Casto-Rebollo, José Salvador Vicente, Patricia Sebastian-Leon, Clara Bueno-Fernandez, Adolfo Rodríguez-Eguren, María Gómez-Álvarez, Amparo Faus, Patricia Diaz-Gimeno, Francisco Marco-Jiménez, Irene Cervelló

“…A subset of embryos was recovered on day 6 for transcriptomic analysis (n = 75–80/group), while the remaining embryos were used to assess implantation and birth rates. …”
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Chronic adolescent stress causes sustained impairment of cognitive flexibility and hippocampal synaptic strength in female rats by M.M. Hyer, G.A. Shaw, P. Goswamee, S.K. Dyer, C.M. Burns, E. Soriano, C.S. Sanchez, S.A. Rowson, A.R. McQuiston, G.N. Neigh

“…Male and female Wistar rats born in-house remained non-stressed (NS), unmanipulated aside from standard cage cleaning, or were exposed to either physical restraint (60 min) or social defeat (CAS) each day (6 trials each), along with social isolation, throughout the adolescent period (PND 35–47). …”
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Preventive effects of resveratrol against early-life impairments in the animal model of autism induced by valproic acid by Gustavo Brum Schwingel, Mellanie Fontes-Dutra, Bárbara Ramos, Rudimar Riesgo, Victorio Bambini-Junior, Carmem Gottfried

“…Method: We monitored gestational weight from embryonic day 6.5 until 18.5 and assessed the onset of developmental milestones and morphometric parameters in litters. …”
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Netupitant/palonosetron (NEPA) and dexamethasone for prevention of emesis in breast cancer patients receiving adjuvant anthracycline plus cyclophosphamide: a multi-cycle, phase II... by Roberta Caputo, Marina Elena Cazzaniga, Andrea Sbrana, Rosalba Torrisi, Ida Paris, Monica Giordano, Vincenzo Montesarchio, Valentina Guarneri, Laura Amaducci, Domenico Bilancia, Giuseppina Cilenti, Alessandra Fabi, Elena Collovà, Alessio Schirone, Erminio Bonizzoni, Luigi Celio, Sabino De Placido, Michelino De Laurentiis

“…The study also describes the relationship between efficacy on day 1 through 5 (overall period) and control of CINV on day 6 through 21 (very late period) in each cycle. …”
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Platelet-rich plasma combined with gypenosides for the treatment of psoriasis-like inflammation in mice by LI Dandan, WANG Bing, GE Yu, CHENG Hong, LI Mengxue, WANG Zhicheng, XIA Rong

“…[Results] At the end of the experiment (on day 6), scale scores of model, PRP, GPs and PRP+GPs group were 3.6±0.49, 1.8±0.75, 1.8±0.75, 1.2±0.40, respectively; the ratios of skin thickness (μm) were 0.86±0.18, 0.59±0.10, 0.56±0.07 and 0.42±0.09; PASI scores were 10.6±1.02, 4.0±0.63, 4.0±1.10 and 3.2±0.75. …”
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Optimization and characterization of oil palm empty fruit bunch fermentation for cellulase production by Botryosphaeria rhodina UPM3 by Kamal Bahrin, Ezyana

“…While β-glucosidase (0.09 U/g) indicated high activity on day 6 of SSF. Maximum FPase activity was obtained at the optimum levels of SSF parameters (fungal agar plug, 30°C incubation temperature,20% initial moisture content, 5.0 g of substrate, initial pH of nutrient at 7.0 and without mixing). …”
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Microencapsulation and flavor stability of spray-dried oleoresin from water dropwort (Oenanthe javanica) and kacip fatimah (Labisia pumila) by Pattiram, Parveen Devi

“…For instance, at drying temperature 170±2 oC, encapsulated water dropwort has reduced to 2 compounds as compared with day 6 (6 compounds). Encapsulated “Kacip Fatimah” also showed the same reduction whereby, a total of 5 compounds were detected at 24 days of storage as compared to 25 compounds detected at 6 days storage. …”
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Bioremediation kinetics of pyrene by microbial consortium isolated from local polluted soil by Ibn Abubakar, Baba Shehu Umar

“…Degradation of 1.5 ppm and 3.0 ppm of Pyr and biomass growth in aqueous medium occurred within six days with a short lag period followed by log phase from day 2- day 6 with moderate specific growth rate, _ at 0.07 h 1 and 0.024 h 1 respectively. …”
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URO protective effect of Luteolin Nano Suspension on Cyclophosphamide-Induced Hemorrhagic Cystitis in rats by Harikumar, Ravindran Pillai

“…Group- 1 (vehicle control) received normal saline (10 ml/kg/b.w/p.o); group-2 (negative control) received three doses of CP (100 mg/kg/b.w/p.o) on day 6, 8, 10; group-3 (positive control) received MESNA (20 mg/kg/b.w/p.o) and group-4 (test) received LNS (30 mg/kg/b.w/p.o). …”
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Characterization and growth optimization of marine fungi, and antibacterial and biofilm removal activities of its extracts by Mat Daud, Noor Ifatul Hanim

“…All bacteria except S. typhimurium, showed highest viable counts (log CFU/cm2) (6.80-7.38) on Day 6 and the counts decreased to lowest (3.98-4.25) on the Day 15 while S. typhimurium reached its maximum counts (7.26±0.05) after 9 days of incubation and decreased to 5.10±0.09 on Day 15. …”
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Use of Lactobacillus plantarum and Propionibacterium freudenreichii ssp. Shermanii as inoculants in corn silage fermentation by Abdul Rahman, Norafizah

“…The time course study in fermentation indicated that the ensilation process was completed at day 6 even without using bacterial additives. …”
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Characterization of T-lymphocyte populations and selected cytokine expressions of chickens vaccinated with H5-recombinant fowl pox viruses co-expressing IL-15 gene by Nor Majid, Nadzreeq

“…The rFPV/H5/IL-15 group showed an increased level of IL-15 and IL-18 genes expression up to 2 and 3.5 folds, respectively, within 6 days post-vaccination, compared with other inoculated groups. rFPV/H5 group showed an increased level of IL-15 gene expression at day 2 and maintained at day 4 until day 6, while the IL-18 expression was decreasing within 6 days. …”
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Culture and characterization of Microcystis spp. and their effects on cladoceran population growth by Shakri, Adibah

“…micrura’s first offspring, which only occurred on day 6 compared to M. micrura fed with C. vulgaris which produced their first offspring on day 3. …”
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Consumo de café y té en población mediterránea de alto riesgo cardiovascular Coffee and tea consumption in a high cardiovascular risk Mediterranean population by M. Sotos-Prieto, P. Carrasco, J. V. Sorlí, M. Guillén, P. Guillém-Sáiz, L. Quiles, D. Corella

“…By contrast, coffee consumption averaged nearly one cup per day (6,5 ± 5,2 cups/weeks). Hypertensive patients showed a lower overall consumption of coffee than in non-hypertensive patients (6,6 ± 5,1 vs 7,3 ± 5,9; P = 0,023 respectively). …”
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A phase I study of weekly doxorubicin and oral topotecan for patients with relapsed or refractory small cell lung cancer (SCLC): A Fred and Pamela Buffet Cancer Center Clinical Tri... by Vinicius Ernani, Rahat Jahan, Lynette M. Smith, Alissa S. Marr, Sarah E. Kimbrough, Mary E. Kos, Jolene Tijerina, Shannon Pivovar, Imayavaramban Lakshmanan, Marsha Ketcham, Sanchita Rauth, Kavita Mallya, Mohd W Nasser, Maneesh Jain, Anne Kessinger, Surinder K. Batra, Apar Kishor Ganti

“…All patients received weekly doxorubicin 20 mg/m2 intravenously starting day 6 of the first cycle and continued weekly for a maximum of 15 weeks. …”
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Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients by Laura Sánchez-de Prada, Laura Sánchez-de Prada, Óscar Gorgojo-Galindo, Óscar Gorgojo-Galindo, Inmaculada Fierro, Ana María Martínez-García, Guillermo Sarmentero-López de Quintana, Rocío Gutiérrez-Bustillo, Rocío Gutiérrez-Bustillo, María Teresa Pelaez-Jareño, Elisa Álvarez-Fuente, Esther Gómez-Sánchez, Esther Gómez-Sánchez, Esther Gómez-Sánchez, Eduardo Tamayo, Eduardo Tamayo, Eduardo Tamayo, Eduardo Tamayo, Álvaro Tamayo-Velasco, Álvaro Tamayo-Velasco, Álvaro Tamayo-Velasco, Marta Martín-Fernández, Marta Martín-Fernández, Marta Martín-Fernández

“…The combined mortality prediction accuracy of PC3 at day 1 and PC1 and PC2 at day 6 is 89.00% (p<0.001).ConclusionsHypercytokinemia is a hallmark of COVID-19 but relevant differences between survivors and non-survivors can be early observed. …”
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Interferences with aerosol acidity quantification due to gas-phase ammonia uptake onto acidic sulfate filter samples by B. A. Nault, B. A. Nault, B. A. Nault, P. Campuzano-Jost, P. Campuzano-Jost, D. A. Day, D. A. Day, H. Guo, H. Guo, D. S. Jo, D. S. Jo, D. S. Jo, A. V. Handschy, A. V. Handschy, D. Pagonis, D. Pagonis, J. C. Schroder, J. C. Schroder, J. C. Schroder, M. K. Schueneman, M. K. Schueneman, M. J. Cubison, J. E. Dibb, A. Hodzic, W. Hu, B. B. Palm, J. L. Jimenez, J. L. Jimenez

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R-Spondin 1 (RSPO1) Increases Mouse Intestinal Organoid Unit Size and Survival in vitro and Improves Tissue-Engineered Small Intestine Formation in vivo by Gabriel Levin, Gabriel Levin, Gabriel Levin, Samuel M. Zuber, Anthony I. Squillaro, Mari Cleide Sogayar, Mari Cleide Sogayar, Mari Cleide Sogayar, Tracy C. Grikscheit, Ana Claudia O. Carreira, Ana Claudia O. Carreira, Ana Claudia O. Carreira

“…The explants were harvested after 30 days, weighed, fixed in formalin and embedded in paraffin for histological analysis and immunofluorescence for different cell markers.Results: After 3 days, rhRSPO1-treated OU attained a larger size, when compared to the control group, becoming 5.7 times larger on day 6. Increased survival was observed from the second day in culture, with a 2-fold increase in OU survival between days 3 and 6. …”
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Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam by Nguyen Lam Vuong, Nguyen Than Ha Quyen, Nguyen Thi Hanh Tien, Kien Duong Thi Hue, Huynh Thi Le Duyen, Phung Khanh Lam, Dong Thi Hoai Tam, Tran Van Ngoc, Thomas Jaenisch, Cameron P Simmons, Sophie Yacoub, Bridget A Wills, Ronald Geskus

“…Higher viremia levels were associated with decreased subsequent platelet counts from day 6 onwards. Elevated viremia levels on each illness day increased the risk of developing severe dengue and plasma leakage. …”
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