Hypoalbuminemia is a predictor of mortality and rebleeding in peptic ulcer bleeding under proton pump inhibitor use by Hsiu-Chi Cheng, Er-Hsiang Yang, Chung-Tai Wu, Wen-Lun Wang, Po-Jun Chen, Meng-Ying Lin, Bor-Shyang Sheu

“…The secondary outcome of recurrent bleeding rates were also increased in the same fashion (0–28th day: 6.4%, 15.4%, 24.6%, p < 0.001; 29th–84th day: 0%, 3.0%, 4.2%, p = 0.01). …”
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Molecular characterisation and pathogenicity of chicken astrovirus isolated from commercial broiler chickens in Malaysia by Abdullahi, Raji Abdullahi

“…In contrast, the exposed sentinel group has a peak mean virus copy number (log10 9.04) on day 6 postinoculation. In conclusion, the isolated Malaysian CAstV is pathogenic in SPF chickens, causing lesions in the gut and kidneys in both the infected and exposed chickens. …”
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Equine chorionic gonadotrophin influences on follicular development, ovulation rate and gestational development in cross-bred goats by Mohamad Mohtar, Mohamad Shuib

“…Based on progesterone concentration analysis, all treatments does except unsuccessful mated does in G3 showed increasing level of progesterone starting on Day 0 (CIDR inserted) until next 6 days. After Day 6, the progesterone level for all treatments does have continuously decline until Day 18 (CIDR removal), 19 and lastly Day 20. …”
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Plant Regeneration And Biochemical Changes in Rice (Oryza Sativa L.) Under NaCl Stress by Khan Khattak, Mohammad Saeed

“…The growth rate of cell suspension of Basmati-370 increased from day 4 up to day 1 0 and the activities of ACP, ALP, GS, MDH, NADP-ICDH and SDH were highest on day 10 while GDH and GOGAT on day 8 and NR on day 6 during the 14 days of culture period. The activities of GDH, GOGAT, NR, ACP, ALP, MDH and NADP-ICDH extracted from NaCI-treated cell suspension of Basmati-3 70 increased while GS and SDH activities decreased. …”
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Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial by Jozefien Declercq, Cedric Bosteels, Karel Van Damme, Elisabeth De Leeuw, Bastiaan Maes, Ans Vandecauter, Stefanie Vermeersch, Anja Delporte, Bénédicte Demeyere, Marnik Vuylsteke, Marianna Lalla, Trevor Smart, Laurent Detalle, René Bouw, Johannes Streffer, Thibo Degeeter, Marie Vergotte, Tanguy Guisez, Eva Van Braeckel, Catherine Van Der Straeten, Bart N. Lambrecht

“…Main outcomes The primary endpoint is the improvement of oxygenation as measured by mean and/or median change from pre-treatment (day 1) to post-treatment (day 6 and 15 or at discharge, whichever comes first) in PaO2/FiO2 ratio, P(A-a)O2 gradient and a/A PO2 ratio. …”
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Exosomes Derived from Dendritic Cells Treated with Schistosoma japonicum Soluble Egg Antigen Attenuate DSS-Induced Colitis by Lifu Wang, Lifu Wang, Lifu Wang, Zilong Yu, Zilong Yu, Zilong Yu, Shuo Wan, Shuo Wan, Shuo Wan, Feng Wu, Wei Chen, Beibei Zhang, Beibei Zhang, Beibei Zhang, Datao Lin, Datao Lin, Datao Lin, Jiahua Liu, Jiahua Liu, Jiahua Liu, Hui Xie, Hui Xie, Hui Xie, Xi Sun, Xi Sun, Xi Sun, Zhongdao Wu, Zhongdao Wu, Zhongdao Wu

“….; 50 μg per mouse) from day 0 to day 6. Clinical scores were calculated based on weight loss, stool type, and bleeding. …”
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Real world effectiveness of early ensitrelvir treatment in patients with SARS-CoV-2, a retrospective case series by Shuichi Abe, Dhammika Leshan Wannigama, Yu Suzuki, Daisuke Akaneya, Junko Igarashi, Mayu Suto, Kazunori Moriya, Daisuke Ishizawa, Yoshikazu Okuma, Parichart Hongsing, Cameron Hurst, Thammakorn Saethang, Paul G. Higgins, Stephen M. Stick, Anthony Kicic

“…Viral loads, as measured by Ct values, increased significantly from 21.82 at symptom onset to 37.65 b y day 6, with SARS-CoV-2 RNA undetectable in most patients by day 9. …”
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Role of intestinal flora and 5-HT in depression- and anxiety-like behaviors in mice exposed to PM2.5 by Jiajie TANG, Jiaxue ZHENG, Qian SONG, Huiwen KANG, Yaqi CUI, Xuemei ZHANG, Xuan SHANG, Shoufang JIANG

“…Mice in the PM group and the PML group were exposed to PM2.5 in a dynamic exposure cabinet for 6 h per day, 6 d a week for 7 consecutive weeks, and the PM2.5 concentrations were approximately 8 times higher than the outdoor concentration. …”
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Matrix Metalloproteinase-9 Relationship With Infarct Growth and Hemorrhagic Transformation in the Era of Thrombectomy by Laura Mechtouff, Laura Mechtouff, Thomas Bochaton, Thomas Bochaton, Alexandre Paccalet, Claire Crola Da Silva, Marielle Buisson, Camille Amaz, Morgane Bouin, Laurent Derex, Elodie Ong, Elodie Ong, Yves Berthezene, Yves Berthezene, Omer Faruk Eker, Nathalie Dufay, Nathan Mewton, Michel Ovize, Michel Ovize, Norbert Nighoghossian, Norbert Nighoghossian, Tae-Hee Cho, Tae-Hee Cho

“…Patients underwent sequential assessment of MMP-9, follow-up CT at day 1, and MRI at day 6. The CT scan at day 1 classified any hemorrhagic transformation according to the European Co-operative Acute Stroke Study-II (ECASS II) classification. …”
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Desempenho de bovinos jovens das raças Aberdeen Angus e Hereford, confinados e alimentados com dois níveis de energia Feedlot performance of young Aberdeen Angus and Hereford steer... by Ivan Luiz Brondani, Alexandre Amstalden Moraes Sampaio, João Restle, Joilmaro Rodrigo Pereira Rosa, Cássio Vieira Marques dos Santos, Maurício dos Santos Fernandes, Fábio Cervo Garagorry, Ivan Heck

“…Animals fed with the higher energy level showed higher DM intakes per day (6.31vs 5.71kg), per 100kg of live weight (2.26 vs 2.11%), per unit of metabolic weight (92.28 vs 85.44g), of digestible energy (DE) (20.58 vs 18.13 Mcal/day) and crude protein (CP) (0.845 vs 0.759 kg/day), beyond a higher daily weight gain (1.409 vs 1.250 kg). …”
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Effect of GSK-3β-mediated DRP1 on inhibition of primary hippocampal neuronal growth induced by aluminum by Meng LI, Liyuan LU, Xiaoyu HE, Changxin XIANG, Xiaoya CAI, Huifang ZHANG

“…BackgroundAluminum (Al) can cause irreversible damage to neurons and synapses function, and the mechanism may be connected to mitochondrial damage caused by glycogen synthase kinase-3β (GSK-3β) regulating dynamin-related protein 1 (DRP1), resulting in inhibition of the growth of neuronal protrusions.ObjectiveTo investigate the role of GSK-3β regulating DRP1 in the inhibition of primary hippocampal neurite growth induced by Al.MethodsNeurons were extracted from the hippocampus of newborn mice (≤24 h old) for primary culture. On day 6, the purity of neurons was detected by immunofluorescence. …”
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Bisphosphonates attenuate age‐related muscle decline in Caenorhabditis elegans by Luke Slade, Shelby E. Bollen, Joseph J. Bass, Bethan E. Phillips, Kenneth Smith, Daniel J. Wilkinson, Nathaniel J. Szewczyk, Philip J. Atherton, Timothy Etheridge

“…ZA (1 μM) significantly improved myofibrillar structure on days 4 and 6 post‐adulthood (83 and 71% well‐organized myofibres, respectively, vs. 56 and 34% controls, P < 0.0001) and increased well‐networked mitochondria at day 6 (47 vs. 16% in controls, P < 0.01). Genes required for ZA‐mediated healthspan extension included fdps‐1/FDPS‐1 (278 ± 9 vs. 894 ± 17% population activity AUC in knockdown + 1 μM ZA vs. untreated controls, respectively, P < 0.0001), daf‐16/FOXO (680 ± 16 vs. 894 ± 17%, P < 0.01) and agxt‐2/BAIBA (531 ± 23 vs. 552 ± 8%, P > 0.05). …”
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ANÁLISIS DE LAS PROPIEDADES DE TEXTURA DURANTE EL ALMACENAMIENTO DE SALCHICHAS ELABORADAS A PARTIR DE TILAPIA ROJA (Oreochromis sp.) ANALISE DAS PROPRIEDADES DE TEXTURA DURANTE O A... by JOSÉ IGOR HLEAP, VIVIANA ANDREA VELASCO

“…Elasticity cohesiveness and adhesiveness showed no significant difference (&alpha; > 0.05) during the time of storage of the sausages, while the elasticity and chewing showed a difference only on day 6 compared with 100. It was concluded that during the time of storage the texture profile parameters and shear force, but had not directly influenced variations in the times of storage of the sausages kept under the conditions listed.…”
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Efeito do tempo da aplicação de prostaglandina na resposta folicular em ovelhas durante o ciclo estral Effect of time of prostaglandin administration on follicular response in ewes... by Luis Fernando Uribe-Velásquez, Maria Inês Lenz Souza, Jose Henry Osorio

“…Number of small follicles (2-2.5 mm) was greater (4.57 ± 0.78 vs 8.42 ± 1.36) at day 6, for PG7 and PG9, respectively, whereas no changes were observed in medium follicles (3-3.5 mm) between groups treated. …”
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Divergent age-related humoral correlates of protection against respiratory syncytial virus infection in older and young adults: a pilot, controlled, human infection challenge model by Stephanie Ascough, PhD, Pete Dayananda, MBChB, Mohini Kalyan, MSc, Seng Ung Kuong, MSc, Zoe Gardener, BSc, Emma Bergstrom, BSc, Suzanna Paterson, MbBChBAO, Satwik Kar, PhD, Vedika Avadhan, MRes, Ryan Thwaites, PhD, Ashley Sanchez Sevilla Uruchurtu, BSc, Tracy J Ruckwardt, PhD, Man Chen, MD, Deepika Nair, MS, Alexandrine Derrien-Colemyn, PhD, Barney S Graham, MD, Malcolm Begg, PhD, Edith Hessel, PhD, Peter Openshaw, ProfFMedSci, Christopher Chiu, ProfPhD

“…Nine (67%) of the 12 older volunteers became infected, developing mild-to-moderate upper respiratory tract symptoms that resolved without serious adverse events or sequelae. Viral load peaked on day 6 post-inoculation and symptoms peaked between days 6 and 8. …”
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Effect of short-term exposure to ambient inhalable particulate matter on daily mortality in six typical cities in central and western Inner Mongolia Autonomous Region, 2017 – 2022:... by Nana WEI, Shengmei YANG, Xiangnan ZHANG, Yaochun FAN, Yuhan QIN, Chenguang ZHANG

“…Cumulative lag effect analysis showed that a 10 μg/m3 increase in daily mean PM10 concentration was associated with increased total non-accidental mortality (ER = 0.25%, 95%CI: 0.08% – 0.42%) and circulatory disease mortality (ER = 0.26%, 95%CI: 0.03% – 0.50%) at lag day 7 in all residents and increased non-accidental mortality in female residents (ER = 0.47%, 95%CI: 0.22% – 0.72%), older residents ≥ 65 years (ER = 0.33%, 95%CI: 0.13% – 0.52%), residents with a junior high school education or less (ER = 0.25%, 95%CI: 0.06% – 0.45%), and married residents (ER = 0.32%, 95%CI: 0.03% – 0.61%); a 10 μg/m3 increase in daily mean PM10 concentration was also associated with increased total non-accidental mortality among married residents (ER = 0.34%, 95%CI : 0.07% – 0.61%) on lag day 6. ConclusionExposure to PM10 is associated with increased total non-accidental mortality and circulatory disease mortality among all residents and the increased total non-accidental mortality and circulatory disease mortality are much more significant among female residents, older residents ≥ 65 years, residents with a junior high school education or less, and unmarried residents in six typical cities in central and western Inner Mongolia.…”
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Nitrate radicals and biogenic volatile organic compounds: oxidation, mechanisms, and organic aerosol by N. L. Ng, S. S. Brown, A. T. Archibald, E. Atlas, R. C. Cohen, J. N. Crowley, D. A. Day, N. M. Donahue, J. L. Fry, H. Fuchs, R. J. Griffin, M. I. Guzman, H. Herrmann, A. Hodzic, Y. Iinuma, J. L. Jimenez, A. Kiendler-Scharr, B. H. Lee, D. J. Luecken, J. Mao, R. McLaren, A. Mutzel, H. D. Osthoff, B. Ouyang, B. Picquet-Varrault, U. Platt, H. O. T. Pye, Y. Rudich, R. H. Schwantes, M. Shiraiwa, J. Stutz, J. A. Thornton, A. Tilgner, B. J. Williams, R. A. Zaveri

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Implementing Germ Defence digital behaviour change intervention via all primary care practices in England to reduce respiratory infections during the COVID-19 pandemic: an efficien... by Ben Ainsworth, Jeremy Horwood, Scott R. Walter, Sascha Miller, Melanie Chalder, Frank De Vocht, James Denison-Day, Martha M. C. Elwenspoek, Helen J. Curtis, Chris Bates, Amir Mehrkar, Seb Bacon, Ben Goldacre, The OpenSAFELY Collaborative, Pippa Craggs, Richard Amlôt, Nick Francis, Paul Little, John Macleod, Michael Moore, Kate Morton, Cathy Rice, Jonathan Sterne, Beth Stuart, Lauren Towler, Merlin L. Willcox, Lucy Yardley

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An online tool for predicting ovarian responses in unselected patients using dynamic inhibin B and basal antimüllerian hormone levels by Congcong Ma, Congcong Ma, Congcong Ma, Congcong Ma, Huiyu Xu, Huiyu Xu, Huiyu Xu, Huiyu Xu, Haiyan Wang, Haiyan Wang, Haiyan Wang, Haiyan Wang, Guoshuang Feng, Yong Han, Kannan Alpadi, Rong Li, Rong Li, Rong Li, Rong Li, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao, Jie Qiao

“…Early Δinhibin B was defined as an increment in inhibin B from menstrual day 2 to day 6 through to the day of COS. Least Absolute Shrinkage and Selection Operator (LASSO) logistic regression with 5-fold cross-validation was applied to construct ovarian response prediction models. …”
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Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants by Muhammad Imtiaz Ashraf, Joerg Mengwasser, Joerg Mengwasser, Anja Reutzel-Selke, Dietrich Polenz, Kirsten Führer, Steffen Lippert, Peter Tang, Edward Michaelis, Rusan Catar, Johann Pratschke, Christian Witzel, Igor M. Sauer, Stefan G. Tullius, Stefan G. Tullius, Barbara Kern, Barbara Kern, Barbara Kern

“…By post-transplantation day 6, skin grafts demonstrated severe rejections, characterized by predominance of recipient CD4 T cells. …”
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