#198 : When to Transfer Day 6 Vitrified Embryos? On Day 5 vs Day 6 of Progesterone, a Retrospective Analysis by Nihar Bhoi, Vipin Chandra, Kshitiz Murdia

“…Conclusion: In this study Frozen Embryo Transfer of D-6 blastocysts on the day-5 of progesterone results in better pregnancy outcomes than the day-6 of progesterone.…”
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Tobacco consumption is associated with slow-growing day-6 blastocysts by Mathilde Bourdon, M.D., Lucile Ferreux, M.D., Chloé Maignien, M.D., Catherine Patrat, M.D., Louis Marcellin, M.D, Ph.D., Khaled Pocate-Cheriet, M.D, Charles Chapron, M.D., Pietro Santulli, M.D., Ph.D.

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Correlation between endometrial dating of luteal phase days 6 and 10 of the same menstrual cycle by Jorge Haddad Filho, Agnaldo Pereira Cedenho, Vilmon de Freitas

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Effects of 15-Days −6° Head-Down Bed Rest on the Attention Bias of Threatening Stimulus by Shan Jiang, YI-Ming Qian, Yuan Jiang, Zi-Qin Cao, Bing-Mu Xin, Bing-Mu Xin, Ying-Chun Wang, Bin Wu

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The effect of day 6 endometrial injury of the ICSI cycle on pregnancy rate: A randomized controlled trial by Ahmed Sherif, Yasser Abou-Talib, Moustafa Ibrahim, Rasha Arafat

“…Aim: To determine the effect of endometrial injury done on day 6 of the ICSI cycle on pregnancy rate. Patients & methods: Sixty qualified patients undergoing IVF/ICSI were randomized to either endometrial injury on day 6 of the cycle or no intervention. …”
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Seminal Plasma Induces Overexpression of Genes Associated with Embryo Development and Implantation in Day-6 Porcine Blastocysts by Cristina A. Martinez, Josep M. Cambra, Maria A. Gil, Inmaculada Parrilla, Manuel Alvarez-Rodriguez, Heriberto Rodriguez-Martinez, Cristina Cuello, Emilio A. Martinez

“…In conclusion, the results demonstrate that SP infusions prior to AI upregulates the expression of embryo development related genes in Day 6 pig embryos.…”
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Day 5 vitrified blastocyst transfer versus day 6 vitrified blastocyst transfer in oocyte donation program by G. M. Yerushalmi, T. Shavit, S. Avraham, M. Youngster, A. Kedem, I. Gat, U. S. Dorofeyeva, S. Mashiach, E. Schiff, A. Shulman, D. S. Seidman, A. Wiser, E. Maman, A. Hourvitz, M. Baum

“…Abstract The superiority of day 5 blastocysts compared to day 6 blastocysts in fresh cycle transfers was previously demonstrated and attributed mainly to endometrial asynchrony. …”
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Comparative Embryo Development Outcomes following Extending Embryo Culture to Day 6: A Retrospective Cohort Study by Clara Q. Wu, Molly Campbell, Doron Shmorgun, Samantha Torrance, Jenna Gale, Marie-Claude Leveille

“…Background: Past studies have shown that culturing slow-growing embryos from day 5 to day 6 may increase vitrification yield. This study aims to evaluate if the proportion of embryos eligible for vitrification increases by growing embryos not vitrified by day 5 to day 6.Materials and Methods: In this retrospective cohort study, a Canadian tertiary-care clinic-based cohort was identified between August 2019 and December 2020. …”
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Effect of 15 days −6° head-down bed rest on microbial communities of supragingival plaque in young men by Di Zhu, Di Zhu, Pengyan Qiao, Qian Zhou, Hui Sun, Hui Sun, Bingmu Xin, Bin Wu, Chuhua Tang, Chuhua Tang

“…Moreover, compared with those at pre-HDBR, the relative abundance of Leptotrichia increased significantly on day 6 of recovery, whereas the relative abundances of Porphyromonas and Streptococcus decreased significantly. …”
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Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos by Tzu-Hsuan Chuang, Tzu-Hsuan Chuang, Chih-Yen Chen, Chin-Sheng Kuan, Hsing-Hua Lai, Chia-Lin Hsieh, Meng-Ju Lee, Yi-Ting Liang, Yu-Jen Chang, Chien-Yu Chen, Shee-Uan Chen

“…Lower mtDNA ratios were observed in the day 6 eSET with adverse outcomes. The present stratification analyses reveal that the timeline of embryo is an important covariate to the mtDNA content.…”
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The Relationship Between Plasma Progesterone Concentration on Day 6 After Artificial Insemination and Pregnancy Rate of Dairy Cows in Vietnam by N. V. Thanh, P. T. Hang, P. V. Gioi, N. C. Toan, S. T. Long

“… The study was conducted to determine the relationship between plasma progesterone (P4) concentration on day 6 following artificial insemination (AI) and the pregnancy rate to provide recommendations for measuring P4 concentration before embryo transfer in cows. …”
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D6 blastocyst transfer on day 6 in frozen-thawed cycles should be avoided: a retrospective cohort study by Huiling Xu, Shumin Qiu, Xiaojing Chen, Suqin Zhu, Yan Sun, Beihong Zheng

“…Abstract Background There is no definitive evidence about the suitable timing to transfer blastocysts formed and cryopreserved on day 6 (D6 blastocysts) in frozen-thawed embryo transfer (FET) cycles. …”
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#105 : Single Day 5 Versus Day 6 Euploid Blastocyst Transfer: The Impact of Embryo Quality on Pregnancy Outcomes by Thang Le, Thuy Nguyen, Quy Phan, Anh Phi, Phuong Giap, Huong Nguyen, Hoang Le

“…The day of biopsy, Day 5 (D5) or Day 6 (D6), and embryo quality have been suggested as influential factors in determining the clinical outcomes of single euploid blastocyst transfers. …”
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REPRODUCTIVE OUTCOMES FOLLOWING FROZEN-THAWED EMBRYO TRANSFER IS SUPERIOR WITH THE TRANSFER OF BLASTOCYSTS EXPANDED ON DAY 5 THAN ON DAY 6 by Aytek ŞIK

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Blastocyst-Bearing Sows Display a Dominant Anti-Inflammatory Cytokine Profile Compared to Cyclic Sows at Day 6 of the Cycle by Inmaculada Parrilla, Cristina A. Martinez, Josep M. Cambra, Xiomara Lucas, Graça Ferreira-Dias, Heriberto Rodriguez-Martinez, Cristina Cuello, Maria A. Gil, Emilio A. Martinez

“…The present study postulated that the anti- and proinflammatory cytokine profile 6 days after the onset of estrus differs between endometria from uninseminated cyclic sows and blastocyst-bearing sows. On Day 6 of the cycle, endometrial explants were collected from sows inseminated or not inseminated during the postweaning estrus and cultured for 22 h. …”
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Increased incidence of live births in implanted day 5 versus day 6 blastocysts following single embryo transfers with PGT-A by Chien-Hong Chen, Chun-I Lee, Chun-Chia Huang, Hsiu-Hui Chen, Chih-Ying Chang, En-Hui Cheng, Pin-Yao Lin, Chung-I Chen, Tsung-Hsien Lee, Maw-Sheng Lee

“…Abstract Elective single-embryo transfers of euploid or low-level mosaic blastocysts were analyzed in this retrospective study to determine the correlations of live birth (LB) probability with embryonic developmental features of implanted day 5 (D5, n = 245) or day 6 (D6, n = 73) blastocysts using time-lapse (TL) monitoring. …”
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#193 : Comparison of the Different Expression of OCT-4, GATA-3 and Clinical Pregnancy Outcome Between the Day 5 and Day 6 Blastocysts by Jui-Hua Lee, Wei-Fang Chang, Shang-Yu Tzeng, Yi-Xuan Lee, Shun-Jen Tan, Ruey-Sheng Wang, Jason Yen-Ping Ho, Shyr-Yeu Lin, Yu-Ming Hu, Chii-Ruey Tzeng

“…Background and Aims: In common experience of in vitro-fertilization (IVF) cycle, blastocysts formed at Day 5 (D5) are regarded as higher quality and are more desirable for embryo transfer compared with those formed at Day 6 (D6). How those delayed D6 embryo differs from D5 embryo is less discussed. …”
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Comparison of clinical outcome between day 5 and day 6 single blastocyst transfers in cycles undergoing preimplantation genetic testing for aneuploidy by Ting-Feng Wu, Ming-Jer Chen, Maw-Sheng Lee, Chun-Chia Huang, Shu-Ting Ho, En-Hui Cheng, Tsung-Hsien Lee

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Tolerability of daily intermittent or continuous short-arm centrifugation during 60-day 6o head down bed rest (AGBRESA study) by Timo Frett, David Andrew Green, Edwin Mulder, Alexandra Noppe, Michael Arz, Willi Pustowalow, Guido Petrat, Uwe Tegtbur, Jens Jordan, Shigehiko Ogoh

“…During the Artificial Gravity Bed Rest with European Space Agency (AGBRESA) 60 day 6° head down tilt bed rest study we compared the tolerability of daily +1 Gz exposure at the center of mass centrifugation, either performed continuously for 30 minutes, or intermittedly (6 x 5 minutes). …”
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Live birth rate following frozen-thawed blastocyst transfer is higher in high-grade day 6 blastocysts than in low-grade day 5 blastocysts by Wenhao Shi, Hanying Zhou, Lijuan Chen, Xia Xue, Juanzi Shi

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