DOENÇA AUTO-IMUNE SUGERINDO AO PET RECIDIVA DE LINFOMA HODGKIN - CONFIRMAÇÃO DA NECESSIDADE DE RE-BIOPSIAR SÍTIOS SUSPEITOS by MP Borim

“…Três meses após repetiu PET- CT - redução das dimensões e intensidade do metabolismo glicolítico nas linfonodomegalias supra e infradiafragmáticas (Deauville 2). VHS 18 mm. Conclui-se agora contexto de doença oncohematológica em remissão, assim como doença reumatológica em controle sob tratamento. …”
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Lesion-to-Liver SUVmax Ratio to Improve the Prognostic Value of the End of Treatment PET/CT in Diffuse Large B-Cell Lymphoma by Cristina Ferrari, Antonio Rosario Pisani, Tamara Masi, Giulia Santo, Paolo Mammucci, Dino Rubini, Angela Sardaro, Giuseppe Rubini

“…After first-line therapy, 30–40% of patients relapse or experiment with refractory disease. 18F-FDG PET/CT represents a validated diagnostic tool in post-treatment evaluation of FDG-avid lymphoma, and the Deauville Score (DS), a five-point visual scale, is usually used to assess response. …”
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How we treat NK/T-cell lymphomas by Eric Tse, Wei-Li Zhao, Jie Xiong, Yok-Lam Kwong

“…Therapeutic goals are to achieve undetectable plasma EBV DNA and normal PET/CT (Deauville score ≤ 3). NK/T-cell lymphomas express the multidrug resistance phenotype, rendering anthracycline-containing regimens ineffective. …”
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Value of 18F-FDG PET/CT in Evaluating Chemotherapeutic Effect of Diffuse Large B Cell Lymphoma Patients with Different CD5 Expression by YANG Ming, FENG Yanlin, XIAN Weijun, LU Shengnan, WANG Ying, LI Wen, HUANG Kemin

“…Methods We retrospectively analyzed the PET/CT manifestation of 55 patients initially diagnosed as DLBCL. Deauville 5-score(5-PS) standard was applied to compare the chemotherapy effect between DLBCL patients with CD5(+) and CD5(-), and analyze if there was difference in age, gender, Ann Arbor staging, B symptoms, invasion position, LDH, IPI or SUVmax in DLBCL patients with different CD5 expression. …”
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Dual-Layer Spectral Detector Computed Tomography Quantitative Parameters: A Potential Tool for Lymph Node Activity Determination in Lymphoma Patients by Hebing Chen, Yuxiang Fang, Jin Gu, Peng Sun, Lian Yang, Feng Pan, Hongying Wu, Tianhe Ye

“…A retrospective analysis of 55 lymphoma patients with 289 lymph nodes, assessed through ¹⁸FDG-PET/CT and the Deauville five-point scale, revealed significantly higher values of nIC, nZeff, nED, and ECV in active lymph nodes compared to inactive ones (<i>p</i> < 0.001). …”
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Patterns of pathologic lymph nodes in anal cancer: a PET-CT-based analysis with implications for radiotherapy treatment volumes by Anna Frennered, Jonas Scherman, Pamela Buchwald, Anders Johnsson, Hanna Sartor, Sophia Zackrisson, Elin Trägårdh, Martin P. Nilsson

“…Methods The baseline [18F]-FDG PET-CTs of 190 consecutive anal cancer patients were retrospectively assessed. LNs with a Deauville score (DS) of ≥3 were defined as PET-positive. …”
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Longitudinal Body Composition Changes Detected by [¹⁸F]FDG PET/CT during and after Chemotherapy and Their Prognostic Role in Elderly Hodgkin Lymphoma by Domenico Albano, Francesco Dondi, Giorgio Treglia, Alessandra Tucci, Marco Ravanelli, Davide Farina, Francesco Bertagna

“…Metabolic response applying Deauville score was evaluated at interim and end-of-treatment PET/CT. …”
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The Utility of Metabolic Parameters on Baseline F-18 FDG PET/CT in Predicting Treatment Response and Survival in Paediatric and Adolescent Hodgkin Lymphoma by Janet Denise Reed, Andries Masenge, Ane Buchner, Fareed Omar, David Reynders, Mariza Vorster, Christophe Van de Wiele, Mike Sathekge

“…Response assessment on end-of-treatment PET was evaluated according to the Deauville criteria. We found that bone marrow involvement (<i>p</i> = 0.028), effusion (<i>p</i> < 0.001), and treatment response (<i>p</i> < 0.001) on baseline PET, as well as HIV status (<i>p</i> = 0.036) and baseline haemoglobin (<i>p</i> = 0.039), were significantly related to progression-free survival (PFS), whereas only effusion (<i>p</i> = 0.017) and treatment response (<i>p</i> = 0.050) were predictive of overall survival (OS). …”
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Prognostic evaluation of extranodal natural killer/T-cell lymphoma, nasal type(ENKTL) with 18F-FDG PET/CT by WANG Jin, GUO Rui, LI Biao, ZHANG Xiaozhe

“…Methods: Forty-one pathologically confirmed ENKTL patients (from October, 2014 to June, 2021) received methotrexate, etoposide, dexamethasone and pegaspargase(MESA) regimen and pre-, mid-, and end-treatment 18F-FDG PET/CT scans were retrospectively analyzed. Deauville score (DS), maximal standardized uptake values (SUVmax) and the change of SUVmax (ΔSUVmax) were recorded for response assessment. …”
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Prognostic values of baseline, interim and end-of therapy 18F-FDG PET/CT in patients with follicular lymphoma by Zhou Y, Zhao Z, Li J, Zhang B, Sang S, Wu Y, Deng S

“…Interim (I-PET) and end-of treatment (E-PET) PET/CT responses were interpreted by Deauville five-point scale (D-5PS) and International Harmonization Project criteria (IHP). …”
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Imaging Features and Prognostic Value of FDG PET/CT in Patients with Intravascular Large B-Cell Lymphoma by Lim CH, Yoon SE, Kim WS, Lee KH, Kim SJ

“…The remaining 22 patients with extranodal (EN) involvement were categorized into Deauville score 3– 4 (EN/DS3-4; n = 14) and DS5 groups (EN/DS5; n = 8). …”
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Baseline total lesion glycolysis combined with interim positron emission tomography‐computed tomography is a robust predictor of outcome in patients with peripheral T‐cell lymphoma... by Akihiro Kitadate, Kentaro Narita, Kouta Fukumoto, Toshiki Terao, Takafumi Tsushima, Hiroki Kobayashi, Yoshiaki Abe, Daisuke Miura, Masami Takeuchi, Youichi Machida, Kosei Matsue

“…All iPET responses were analyzed using the Deauville 5‐point scale. Results On univariate analysis, a prognostic index for PTCL (PIT) higher than 2 (hazard ratio [HR], 2.03; P = .026), high TMTV (>389 cm3; HR, 2.24; P = .01), high TLG (>875; HR, 3.77; P = .0005), and positive iPET (HR, 2.18; P = .009) were significantly associated with poorer progression‐free survival (PFS). …”
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Limited benefit of additional contrast-enhanced CT to end-of-treatment PET/CT evaluation in patients with follicular lymphoma by Gaetano Paone, Mariana Raditchkova-Sarnelli, Teresa Ruberto-Macchi, Marco Cuzzocrea, Emanuele Zucca, Luca Ceriani, Luca Giovanella

“…Two blinded observers independently assessed PET/ldCT and PET/ceCT applying the Deauville score (DS) and Lugano classification criteria. …”
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Significance of metabolic parameters and biochemical indexes of 18F-FDG PET/CT in the mid-term evaluation and prognosis of diffuse large B-cell lymphoma by Zhang Fan, Zhang Guoxu, Liu Xiuting, Wang Jigang, Liu Yanqin, Tong Danjiang, Liu Jinghua, Zhou Fan

“…The proportion of patients who achieved complete remission （CR） was statistically compared among different clinical indexes（&#x003b2;2-microglobulin （&#x003b2;2-MG）, dual expression, triple expression, Ann Arbor stage, international prognostic index （IPI） and Deauville 5-point scale （D5PS） score） and metabolic parameters of 18F-FDG-PET/CT （the maximum standardized uptake value （SUVmax）, the sum of the maximum standardized uptake value （SUVmaxsum）, the mean standardized uptake value （SUVmean） and the maximum decrease range of SUV （&#x025B3;SUVmax））. …”
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Evaluation of therapeutic effect and prognostic value of 18F-FDG PET/CT in different treatment nodes of DLBCL patients by Wenyu Zhao, Xiaodong Wu, Shuo Huang, Hui Wang, Hongliang Fu

“…ΔSUVmax and ΔTMTV were the same algorithm. The visual Deauville 5-point scale (D-5PS) has been adopted as the major criterion for PET evaluation. …”
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The prognostic significance of [18F]FDG PET/CT in multiple myeloma according to novel interpretation criteria (IMPeTUs) by Christos Sachpekidis, Maximilian Merz, Marc-Steffen Raab, Uta Bertsch, Vivienn Weru, Annette Kopp-Schneider, Anna Jauch, Hartmut Goldschmidt, Antonia Dimitrakopoulou-Strauss

“…PET/CT analysis was based on the IMPeTUs criteria, which take into consideration—among others—the metabolic state of the bone marrow based on the 5-point Deauville score (DS), the number and metabolic state of focal [18F]FDG-avid lesions, as well as the presence of paramedullary disease (PMD) and extramedullary disease (EMD). …”
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Investigator choice of standard therapy versus sequential novel therapy arms in the treatment of relapsed follicular lymphoma (REFRACT): study protocol for a multi-centre, open-lab... by Graham McIlroy, Siân Lax, Charlotte Gaskell, Aimee Jackson, Malcolm Rhodes, Tania Seale, Sonia Fox, Lousie Hopkins, Jessica Okosun, Sally F. Barrington, Ingo Ringshausen, Alan G. Ramsay, Maria Calaminici, Kim Linton, Mark Bishton

“…The primary outcome is complete metabolic response by PET-CT at 24 weeks using the Deauville 5-point scale and Lugano 2014 criteria. Secondary outcomes include overall metabolic response, progression-free survival, overall survival, duration of response, and quality of life assessed by EQ-5D-5 L and FACT-Lym. …”
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Role of 18F-Fluorodeoxyglucose–Positron Emission Tomography/Computed Tomography Imaging in the Prediction of Prognosis in Patients With Indolent Lymphoma: Prospective Study by Nawal Faiez AlShehry, Raja Shanker, Syed Ziauddin Ahmed Zaidi, Fahad AlGhmlas, Ibraheem Hussein Motabi, Shahid Iqbal, Ahmad Ali Butt, Hassan AlShehri, Imran Khan Tailor, Syed Yasir Altaf, Mubarak AlGhamdi, Mohammed Marie, Mansour AlFayez, Kamal Al Zahrani, Mohammed Dwaimah, Tahani Al-Halouli, Wafaa Al-Shakweer, Maied Zaher AlShehery, Abdul Rehman Zia Zaidi, Atta Munawar Gill, Belal Mohammed Albtoosh, Musab Ahmed

“…Metabolic response on follow-up PET/CT was assessed using the maximum standardized uptake value (SUVmax) and Deauville criteria (DC). We aimed to obtain the best SUVmax and DC to predict optimal survival rates, risk stratification, and optimize therapeutic strategies. …”
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Interim FDG-PET/CT for therapy monitoring and prognostication in Hodgkin’s Lymphoma by Akram Al-Ibraheem, Farah Anwer, Malik E. Juweid, Qaid Ahmed Shagera, Aysar N. Khalaf, Shahed Obeidat, Areen Mansour, Mohammad Ma’koseh, Khalid Halahleh, Imad Jaradat, Nidal Almasri, Asem Mansour

“…The response status on iPET was defined according to the standard five-point Deauville scores (DS) as follows: complete metabolic response (CMR, DS 1–3) and non-complete metabolic response (nCMR) (DS 4 and 5). …”
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Baseline ¹⁸F-FDG PET/CT Radiomics in Classical Hodgkin’s Lymphoma: The Predictive Role of the Largest and the Hottest Lesions by Elizabeth Katherine Anna Triumbari, Roberto Gatta, Elena Maiolo, Marco De Summa, Luca Boldrini, Marius E. Mayerhoefer, Stefan Hohaus, Lorenzo Nardo, David Morland, Salvatore Annunziata

“…Two bPET/CT target lesions were selected for radiomic feature extraction: Lesion_A, with the largest axial diameter, and Lesion_B, with the highest SUV_max. Deauville score at interim PET/CT (DS) and 24-month progression-free-survival (PFS) were recorded. …”
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