Showing 1 - 20 results of 320 for search '"Delta II"', query time: 1.05s Refine Results
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    A new mouse allele of glutamate receptor delta 2 with cerebellar atrophy and progressive ataxia. by Yuka Miyoshi, Yoshichika Yoshioka, Kinuko Suzuki, Taisuke Miyazaki, Minako Koura, Kazumasa Saigoh, Naoko Kajimura, Yoko Monobe, Susumu Kusunoki, Junichiro Matsuda, Masahiko Watanabe, Naoto Hayasaka

    Published 2014-01-01
    “…Based on the phenotypic similarities of the ts3 mutant with other known ataxic mutants, we performed immunohistological analyses and found that expression levels of two genes and their products, glutamate receptor delta2 (grid2) and its ligand, cerebellin1 (Cbln1), are significantly reduced or undetectable. …”
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    Loss of Gap Junction Delta-2 (GJD2) gene orthologs leads to refractive error in zebrafish by Wim H. Quint, Kirke C. D. Tadema, Erik de Vrieze, Rachel M. Lukowicz, Sanne Broekman, Beerend H. J. Winkelman, Melanie Hoevenaars, H. Martijn de Gruiter, Erwin van Wijk, Frank Schaeffel, Magda Meester-Smoor, Adam C. Miller, Rob Willemsen, Caroline C. W. Klaver, Adriana I. Iglesias

    Published 2021-06-01
    “…Quint et al. use zebrafish lines deficient in one of two orthologs of the Gap Junction Delta-2 (GJD2) gene, which is associated with myopia by genome-wide association studies. …”
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    Choosing the target difference ('effect size') for a randomised controlled trial - DELTA(2) guidance protocol. by Cook, JA, Julious, SA, Sones, W, Rothwell, JC, Ramsay, CR, Hampson, LV, Emsley, R, Walters, SJ, Hewitt, C, Bland, M, Fergusson, DA, Berlin, JA, Altman, D, Vale, LD

    Published 2017
    “…This article reports the protocol of the Difference ELicitation in TriAls (DELTA(2)) project, which will produce guidance on the specification and reporting of the target difference for the primary outcome in a sample size calculation for RCTs.…”
    Journal article
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    Neurodevelopmental Syndrome with Intellectual Disability, Speech Impairment, and Quadrupedia Is Associated with Glutamate Receptor Delta 2 Gene Defect by Anastasia P. Grigorenko, Maria S. Protasova, Alexandra A. Lisenkova, Denis A. Reshetov, Tatiana V. Andreeva, Gilberto De Lima Garcias, Maria Da Graça Martino Roth, Andreas Papassotiropoulos, Evgeny I. Rogaev

    Published 2022-01-01
    “…Using whole-genome sequencing analysis and homozygous genetic mapping, we identified genes bearing homozygous genetic variants and found a homozygous 36.2 kb deletion in the gene of glutamate receptor delta 2 (<i>GRID2</i>) in the patients, resulting in the lack of a coding region from the fifth to the seventh exons. …”
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    On the spectrum of 2-nd order generalized difference operator $\delta^2$ over the sequence space $c_0$ by S. Dutta, Pinakadhar Baliarsingh

    Published 2013-12-01
    “…The main purpose of  this article is to  determine the spectrum and the fine spectrum  of second order  difference operator $\Delta^2$  over the sequence space $c_0$. For any sequence $(x_k)_0^\infty$ in $c_0$, the generalized second order  difference operator $\Delta^2$  over  $c_0$ is defined by $\Delta^2(x_k)= \sum_{i=0}^2(-1)^i\binom{2}{i}x_{k-i}=x_k-2x_{k-1}+x_{k-2}$, with $ x_{n}  = 0$ for $n<0$.Throughout we use the convention that a term with a negative subscript is equal to zero.…”
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    Mitochondrial morphogenesis, dendrite development, and synapse formation in cerebellum require both Bcl-w and the glutamate receptor delta2. by Qiong A Liu, Helen Shio

    Published 2008-06-01
    “…Bcl-w belongs to the prosurvival group of the Bcl-2 family, while the glutamate receptor delta2 (Grid2) is an excitatory receptor that is specifically expressed in Purkinje cells, and required for Purkinje cell synapse formation. …”
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    DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial by Cook, J, Julious, S, Sones, W, Hampson, L, Hewitt, C, Berlin, J, Ashby, D, Emsley, R, Fergusson, D, Walters, S, Wilson, E, Maclennan, G, Stallard, N, Rothwell, J, Bland, M, Brown, L, Ramsay, C, Cook, A, Armstrong, D, Altman, D, Vale, L

    Published 2018
    “…In this article, the key messages from the DELTA2 guidance on determining the target difference and sample size calculation for a randomised controlled trial are presented. …”
    Journal article
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    Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA2 guidance by Sones, WR, Julious, SA, Rothwell, J, Ramsay, C, Hampson, L, Emsley, R, Walters, S, Hewitt, C, Bland, M, Fergusson, D, Berlin, J, Altman, D, Vale, L, Cook, JA

    Published 2018
    “…This article reports the development of the DELTA2 guidance on the specification and reporting of the target difference for the primary outcome in a sample size calculation for an RCT.…”
    Journal article
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    Chitosan Nanoparticles Strengthen V&gamma;9V&delta;2 T-Cell Cytotoxicity Through Upregulation Of Killing Molecules And Cytoskeleton Polarization by Lin L, He J, Li J, Xu Y, Li J, Wu Y

    Published 2019-11-01
    “…As one of several promising candidates for immunotherapy, V&gamma;9V&delta;2 &gamma;&delta; T cells have many unique biological advantages, such as non-MHC restriction and have been noted as the earliest source of IFN-&gamma;. …”
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    Practical help for specifying the target difference in sample size calculations for RCTs: the DELTA2 five-stage study, including a workshop by Jonathan A Cook, Steven A Julious, William Sones, Lisa V Hampson, Catherine Hewitt, Jesse A Berlin, Deborah Ashby, Richard Emsley, Dean A Fergusson, Stephen J Walters, Edward CF Wilson, Graeme MacLennan, Nigel Stallard, Joanne C Rothwell, Martin Bland, Louise Brown, Craig R Ramsay, Andrew Cook, David Armstrong, Douglas Altman, Luke D Vale

    Published 2019-10-01
    “…Methods: The Difference ELicitation in TriAls2 (DELTA2) recommendations and advice were developed through a five-stage process, which included two literature reviews of existing funder guidance and recent methodological literature; a Delphi process to engage with a wider group of stakeholders; a 2-day workshop; and finalising the core document. …”
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