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Deletion of voltage-gated calcium channels in astrocytes decreases neuroinflammation and demyelination in a murine model of multiple sclerosis
Published 2023-11-01Subjects: Get full text
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Anti-Neurofascin Antibodies Associated with White Matter Diseases of the Central Nervous System: A Red Flag or a Red Herring?
Published 2022-08-01Subjects: Get full text
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Editorial: Demyelinating neurological syndromes: The role of autoimmunity
Published 2023-03-01Subjects: “…demyelinating diseases…”
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Nerve Growth Factor Neutralization Promotes Oligodendrogenesis by Increasing miR-219a-5p Levels
Published 2021-02-01Subjects: Get full text
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Anti-MOG Antibody-Associated Unilateral Cortical Encephalitis with Bilateral Meningeal Involvement: A Case Report
Published 2023-02-01Subjects: Get full text
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188
Developing Hypoimmunogenic Human iPSC‐Derived Oligodendrocyte Progenitor Cells as an Off‐The‐Shelf Cell Therapy for Myelin Disorders
Published 2023-08-01Subjects: Get full text
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189
Reduced serum IgG galactosylation is associated with increased inflammation during relapses of neuromyelitis optica spectrum disorders
Published 2024-03-01Subjects: Get full text
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A cross‐sectional study of MRI features and the gut microbiome in pediatric‐onset multiple sclerosis
Published 2024-02-01“…Methods A cross‐sectional study involving the Canadian Paediatric Demyelinating Disease Network study participants. Gut microbiome features (alpha diversity, phylum‐ and genus‐level taxa) were derived using 16S rRNA sequencing from stool samples. …”
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192
Study of the mechanisms by which CD4+ T cells contribute to protection in Theiler's murine encephalomyelitis.
Published 1993“…However, surviving animals had high levels of persisting virus in the CNS and they developed very severe symptoms of chronic demyelinating disease. The appearance of infectious virus was not due to selection of neutralizing antibody-resistant viral variants. …”
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A Tumefactive Multiple Sclerosis Case Mimicking a Focal Cerebral Mass
Published 2013-04-01“…Tumefactive multiple sclerosis is a rare demyelinating disease presenting with a focal cerebral mass. …”
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Critical role of TLR activation in viral replication, persistence, and pathogenicity of Theiler’s virus
Published 2023-04-01“…Theiler’s murine encephalomyelitis virus (TMEV) establishes persistent viral infections in the central nervous system and induces chronic inflammatory demyelinating disease in susceptible mice. TMEV infects dendritic cells, macrophages, B cells, and glial cells. …”
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The role of CD8+T cells in the acute and chronic phases of Theiler's murine encephalomyelitis virus-induced disease in mice.
Published 1992“…Mice rendered CD8-deficient prior to infection with TMEV were less efficient at clearing virus from the central nervous system compared to intact animals and also suffered demyelinating disease of earlier onset and increased severity. …”
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Intracranial Inoculation Is More Potent Than Intranasal Inoculation for Inducing Optic Neuritis in the Mouse Hepatitis Virus-Induced Model of Multiple Sclerosis
Published 2018-09-01“…Intracranial inoculation should continue to be considered a preferred method for studies of MHV-induced optic neuritis and central nervous system (CNS) demyelinating disease.…”
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A Case Report of Pediatric Patient with Tuberous Sclerosis and Radiologically Isolated Syndrome
Published 2023-05-01“…Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the CNS characterized by symptomatic episodes that occur months or years apart and affect different anatomic locations. …”
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Infection and Activation of B Cells by Theiler’s Murine Encephalomyelitis Virus (TMEV) Leads to Autoantibody Production in an Infectious Model of Multiple Sclerosis
Published 2020-07-01“…Theiler’s murine encephalomyelitis virus (TMEV) induces immune-mediated inflammatory demyelinating disease in susceptible mice that is similar to human multiple sclerosis (MS). …”
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Acute Myelopathy in Childhood
Published 2021-11-01“…Assessment should include neuroimaging of the brain and spinal cord, with further investigations targeted based on the most likely differential diagnoses; for example, a child with suspected demyelinating disease may require specialist cerebrospinal fluid and serological testing. …”
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