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221
Pregnancy and neuromyelitis optica
Published 2016-10-01“…<p>Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease, which mainly affects the optic nerve and spinal cord. …”
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222
Role of therapeutic plasma exchange in neuromyelitis optica: A case series
Published 2022-01-01“…Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the optic nerves and spinal cord and generally has a relapsing course. …”
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223
Rehabilitation treatment in multiple sclerosis
Published 2018-07-01“…Multiple sclerosis (Latin: sclerosis multiplex, SM) it is a chronic demyelinating disease, which requires a comprehensive and continuous physiotherapy By improving the complexity of therapy, the lifespan of patients with multiple sclerosis has been equal to the average life expectancy of a healthy individual. …”
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224
Neuromyelitis optica spectrum disorders in pediatric patients
Published 2018-04-01“…Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord. …”
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225
Practice current: how do you treat neuromyelitis optica?
Published 2017“…It is estimated to affect about 1-3 individuals per 100,000 in the general world population, but is overrepresented in nonwhite populations (particularly Asians and those of Afro-Caribbean descent) as a major proportion of CNS demyelinating disease. 1-5 It follows a relapsing course in the majority of individuals, and most patients have early disability due to severe relapses; within 5 years of disease onset, over 50% of patients with relapsing NMO are blind in one eye or both eyes or require ambulatory support. 6,7…”
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226
Genetics of multiple sclerosis.
Published 1998“…Multiple sclerosis (MS) is a common demyelinating disease of the central nervous system affecting primarily young adults. …”
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227
The emerging role of vitamin D binding protein in multiple sclerosis.
Published 2011“…Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS). …”
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228
B cells in multiple sclerosis
Published 2017-01-01“…Multiple sclerosis is commonly considered as an autoimmune demyelinating disease, where myelin-reactive T cells enter the CNS from outside, and drive the inflammatory changes that ultimately create the degenerative MS plaque. …”
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229
Optical coherence tomography – a useful examination in the fight against multiple sclerosis
Published 2018-12-01“…Multiple sclerosis is a demyelinating disease that affects the young adult and produces major disability. …”
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230
Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report
Published 2023-03-01“…Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal, demyelinating disease of the central nervous system. The disease almost exclusively presents in immunosuppressed patients, such as those with acquired immunodeficiency syndrome, a hematopoietic malignancy, or a transplanted organ; it is extremely rare in patients without immunosuppression. …”
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231
Comorbidity of Bipolar Disorder and Multiple Sclerosis: A Case Report
Published 2013-08-01“…Multiple sclerosis is a chronic demyelinating disease of a central nervous system. Neuropsychiatric symptoms are common in multiple sclerosis and bipolar disorder is one of the most common psychiatric disorders that coexist with multiple sclerosis. …”
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232
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing
Published 2024-02-01“…Genetic alterations in the PLP1 gene, i.e. point mutations and duplications, are associated with demyelinating disease Pelizaeus-Merzbacher. Here, we describe the generation of a human iPSC line harboring a PLP1 variant in codon 33 which leads to an amino acid change from cysteine to tyrosine. …”
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233
MOG antibody associated disorder (MOGAD)
Published 2021-01-01“…The existence of antibodies to myelin oligodendrocyte glycoprotein (MOG) in some patients with CNS demyelinating disease has been recognised for 30 years, but their clinical utility as biomarkers, and potential pathogenicity in humans has only become apparent in the past 15 years. …”
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234
Recurrent tumefactive demyelinating lesions in an elderly woman
Published 2022-12-01“…This case highlights several atypical features associated with tumefactive demyelinating disease, including an older age of onset and recurrent, treatment-resistant lesions. …”
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235
Update on immunopathogenesis and immunotherapy in multiple sclerosis
Published 2013-04-01“…Rebecca C Selter,1 Bernhard Hemmer1–3 1Department of Neurology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany; 2Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; 3Competence Network on Multiple Sklerosis, Munich, Germany Abstract: Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. Both genetic and environmental factors are believed to contribute to the pathogenesis of the disease. …”
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236
AIDS-related progressive multifocal leukoencephalopathy
Published 2020-12-01“…Abstract INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV). …”
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237
Risk factors increasing the incidence of multiple sclerosis (MS)
Published 2022-08-01“… Multiple sclerosis is a chronic demyelinating disease. The etiology of MS is complex and can be associated with many different factors acting simultaneously or in a cascade. …”
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238
Newly Diagnosed Multiple Sclerosis Presenting as Brown-Séquard Syndrome: A Case Report
Published 2022-05-01“…Conclusion: This case highlights the need to have demyelinating disease on the differential as an exceedingly rare, but important, possible cause of Brown-Séquard syndrome.…”
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239
Leucoencefalopatía hipóxica tardía Delayed Hypoxic Leukoencephalopathy
Published 2012-06-01“…<br>Delayed Hypoxic Leukoencephalopathy (DHL) is a rare demyelinating disease. This condition occurs days or weeks after a hypoxic-anoxic injury. …”
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240
Double Filtration Plasmapheresis in the Treatment of a Case with Acute Disseminated Encephalomyelitis
Published 2013-06-01“…Acute disseminated encephalomyelitis (ADEM), is a monophasic autoimmune demyelinating disease of the central nervous system. Although high-dose steroid management has been considered the mainstay of treatment for ADEM, some patients are unresponsive to steroid therapy. …”
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