Pregnancy and neuromyelitis optica by Qiu-ying MA, Jia-wei WANG

“…<p>Neuromyelitis optica (NMO) is an idiopathic inflammatory demyelinating disease, which mainly affects the optic nerve and spinal cord. …”
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Role of therapeutic plasma exchange in neuromyelitis optica: A case series by Rashmi Parashar, Amit Sharma, Ankit Sharma

“…Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the optic nerves and spinal cord and generally has a relapsing course. …”
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Rehabilitation treatment in multiple sclerosis by Katarzyna Ciechanowska, Alicja Roeske

“…Multiple sclerosis (Latin: sclerosis multiplex, SM) it is a chronic demyelinating disease, which requires a comprehensive and continuous physiotherapy By improving the complexity of therapy, the lifespan of patients with multiple sclerosis has been equal to the average life expectancy of a healthy individual. …”
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Neuromyelitis optica spectrum disorders in pediatric patients by Yu. V. Tokareva, A. S. Kotov, M. V. Panteleeva, M. S. Bunak

“…Neuromyelitis optica spectrum disorders (NMOSDs) is an inflammatory demyelinating disease of the central nervous system with a selective injury of the optic nerves and spinal cord. …”
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Practice current: how do you treat neuromyelitis optica? by Ganesh, A

“…It is estimated to affect about 1-3 individuals per 100,000 in the general world population, but is overrepresented in nonwhite populations (particularly Asians and those of Afro-Caribbean descent) as a major proportion of CNS demyelinating disease. 1-5 It follows a relapsing course in the majority of individuals, and most patients have early disability due to severe relapses; within 5 years of disease onset, over 50% of patients with relapsing NMO are blind in one eye or both eyes or require ambulatory support. 6,7…”

Genetics of multiple sclerosis. by Ebers, G, Dyment, D

“…Multiple sclerosis (MS) is a common demyelinating disease of the central nervous system affecting primarily young adults. …”

The emerging role of vitamin D binding protein in multiple sclerosis. by Disanto, G, Ramagopalan, S, Para, A, Handunnetthi, L

“…Multiple sclerosis (MS) is the most common demyelinating disease of the central nervous system (CNS). …”

B cells in multiple sclerosis by Hartmut Wekerle

“…Multiple sclerosis is commonly considered as an autoimmune demyelinating disease, where myelin-reactive T cells enter the CNS from outside, and drive the inflammatory changes that ultimately create the degenerative MS plaque. …”
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Optical coherence tomography – a useful examination in the fight against multiple sclerosis by Anabella-Cristiana Cioabla, Cecilia Adumitresi, Ninela Radulescu, Ileana Ion

“…Multiple sclerosis is a demyelinating disease that affects the young adult and produces major disability. …”
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Progressive multifocal leukoencephalopathy selectively affecting Broca's and Wernicke's areas in an immunocompetent patient: A case report by Renaid B. Kim, BS, David N. Irani, MD, John Kim, MD

“…Progressive multifocal leukoencephalopathy (PML) is a rare, often fatal, demyelinating disease of the central nervous system. The disease almost exclusively presents in immunosuppressed patients, such as those with acquired immunodeficiency syndrome, a hematopoietic malignancy, or a transplanted organ; it is extremely rare in patients without immunosuppression. …”
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Comorbidity of Bipolar Disorder and Multiple Sclerosis: A Case Report by Necla Keskin, Soner Cakmak, Lut Tamam, Ahmet Turan Evlice

“…Multiple sclerosis is a chronic demyelinating disease of a central nervous system. Neuropsychiatric symptoms are common in multiple sclerosis and bipolar disorder is one of the most common psychiatric disorders that coexist with multiple sclerosis. …”
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Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing by Marie-Kristin Schreiber, Maria-Patapia Zafeiriou

“…Genetic alterations in the PLP1 gene, i.e. point mutations and duplications, are associated with demyelinating disease Pelizaeus-Merzbacher. Here, we describe the generation of a human iPSC line harboring a PLP1 variant in codon 33 which leads to an amino acid change from cysteine to tyrosine. …”
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MOG antibody associated disorder (MOGAD) by Lilley Kate, Sudarshini Ramanathan, Russell C Dale, Fabienne Brilot, Simon Broadley

“…The existence of antibodies to myelin oligodendrocyte glycoprotein (MOG) in some patients with CNS demyelinating disease has been recognised for 30 years, but their clinical utility as biomarkers, and potential pathogenicity in humans has only become apparent in the past 15 years. …”
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Recurrent tumefactive demyelinating lesions in an elderly woman by Erika L. Weil, MD, Mohammad Obadah Nakawah, MD

“…This case highlights several atypical features associated with tumefactive demyelinating disease, including an older age of onset and recurrent, treatment-resistant lesions. …”
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Update on immunopathogenesis and immunotherapy in multiple sclerosis by Selter RC, Hemmer B

“…Rebecca C Selter,1 Bernhard Hemmer1&ndash;3 1Department of Neurology, Klinikum Rechts der Isar, Technische Universit&auml;t M&uuml;nchen, Munich, Germany; 2Munich Cluster for Systems Neurology (SyNergy), Munich, Germany; 3Competence Network on Multiple Sklerosis, Munich, Germany Abstract: Multiple sclerosis is a chronic inflammatory demyelinating disease of the central nervous system. Both genetic and environmental factors are believed to contribute to the pathogenesis of the disease. …”
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AIDS-related progressive multifocal leukoencephalopathy by Carolina de Oliveira Abrão, Lissa Rodrigues Machado da Silva, Luiz Carlos Silva Souza, Nathalia de Mello Bisso, Marília Dalva Turchi, Adriana Oliveira Guilarde

“…Abstract INTRODUCTION: Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by reactivation of JC virus (JCV). …”
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Risk factors increasing the incidence of multiple sclerosis (MS) by Monika Kuc, Agnieszka Siedlak, Katarzyna Cyboran, Dominik Machaj, Alicja Płaczek

“… Multiple sclerosis is a chronic demyelinating disease. The etiology of MS is complex and can be associated with many different factors acting simultaneously or in a cascade. …”
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Newly Diagnosed Multiple Sclerosis Presenting as Brown-Séquard Syndrome: A Case Report by Shelby Hoebee, Levi Howard, James Komara, Megan McElhinny

“…Conclusion: This case highlights the need to have demyelinating disease on the differential as an exceedingly rare, but important, possible cause of Brown-Séquard syndrome.…”
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Leucoencefalopatía hipóxica tardía Delayed Hypoxic Leukoencephalopathy by Pablo Sartori, Rolando Giannaula, Gabriela Orzuza

“…<br>Delayed Hypoxic Leukoencephalopathy (DHL) is a rare demyelinating disease. This condition occurs days or weeks after a hypoxic-anoxic injury. …”
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Double Filtration Plasmapheresis in the Treatment of a Case with Acute Disseminated Encephalomyelitis by Mehmet Uğur Çevik, Mehmet Guli Çetinçakmak, Sefer Varol, Eşref Akıl

“…Acute disseminated encephalomyelitis (ADEM), is a monophasic autoimmune demyelinating disease of the central nervous system. Although high-dose steroid management has been considered the mainstay of treatment for ADEM, some patients are unresponsive to steroid therapy. …”
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