Interfering with the CCL2-glycosaminoglycan axis as a potential approach to modulate neuroinflammation by Gschwandtner, M, Piccinini, A, Gerlza, T, Adage, T, Kungl, A

“…Multiple Sclerosis, a chronic inflammatory demyelinating disease of the central nervous system, involves increased expression of monocyte chemotactic protein 1 MCP1-/CCL2. …”

Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis. by Pomeroy, I, Matthews, P, Frank, J, Jordan, E, Esiri, M

“…We believe that this tool can be exploited in future studies to investigate the aetiology, development and clinical significance of cortical lesions in demyelinating disease.…”

The contribution of demyelination to axonal loss in multiple sclerosis. by DeLuca, G, Williams, K, Evangelou, N, Ebers, G, Esiri, M

“…The traditional notion that multiple sclerosis is a primary demyelinating disease has led to a plaque-centred view of both aetiology and the pathogenesis of disease progression. …”

Multiparametric MRI dataset for susceptibility-based radiomic feature extraction and analysis by Fiscone, C, Sighinolfi, G, Manners, DN, Motta, L, Venturi, G, Panzera, I, Zaccagna, F, Rundo, L, Lugaresi, A, Lodi, R, Tonon, C, Castelli, M

“…Multiple sclerosis (MS) is a progressive demyelinating disease impacting the central nervous system. …”

Demyelinated neocortical lesions in marmoset autoimmune encephalomyelitis mimic those in multiple sclerosis. by Pomeroy, I, Matthews, P, Frank, J, Jordan, E, Esiri, M

“…We believe that this tool can be exploited in future studies to investigate the aetiology, development and clinical significance of cortical lesions in demyelinating disease.…”

Comprehensive proteomic analysis of JC polyomavirus-infected human astrocytes and their extracellular vesicles by Larise Oberholster, Amandine Mathias, Sylvain Perriot, Emma Blaser, Mathieu Canales, Samuel Jones, Lucas Culebras, Marie Gimenez, G. Campbell Kaynor, Alexey Sapozhnik, Kevin Richetin, Susan Goelz, Renaud Du Pasquier

“…IMPORTANCE Progressive multifocal leukoencephalopathy is a crimpling demyelinating disease of the central nervous system caused by JC polyomavirus (JCPyV). …”
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Auditory central pathways in children and adolescents with multiple sclerosis by Dayane Aparecida Nascimento Barbosa, Liliane Aparecida Fagundes Silva, Alessandra Giannella Samelli, José Albino da Paz, Carla Gentile Matas

“… Background Multiple sclerosis (MS) is an inflammatory demyelinating disease. Auditory evoked potential studies have demonstrated conduction and neural processing deficits in adults with MS, but little is known about the electrophysiological responses in children and adolescents.…”
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Pattern Clustering of Symmetric Regional Cerebral Edema on Brain MRI in Patients with Hepatic Encephalopathy by Chun Geun Lim, Hui Joong Lee

“…Purpose Metabolic abnormalities in hepatic encephalopathy (HE) cause brain edema or demyelinating disease, resulting in symmetric regional cerebral edema (SRCE) on MRI. …”
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Neuromyelitis Optica: A Case Report by Wei-Chia Chia, Jian-Nan Wang, Ming-Chi Lai

“…Neuromyelitis optica (NMO, Devic's syndrome) is a demyelinating disease of the central nervous system that predominantly affects the spinal cord and optic nerves. …”
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Health Disparities in Multiple Sclerosis among Hispanic and Black Populations in the United States by Michael Z. Moore, Carlos A. Pérez, George J. Hutton, Hemali Patel, Fernando X. Cuascut

“…Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS). …”
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MS and Environmental Factors (ORP-61) by Mehdi Moghadasi

“…Introduction: Multiple sclerosis (MS) is a potentially disabling acquired demyelinating disease of central nervous system. We do not know for certain what causes multiple sclerosis. …”
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Depressive disorders in comorbidity with Multiple Sclerosis. Case study by E. Shaska

“… Introduction Multiple Sclerosis is a neurodegenerative, demyelinating disease that affects the Central Nervous System. …”
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The importance of mouse models to define immunovirologic determinants of progressive multifocal leukoencephalopathy by Aron eLukacher, Elizabeth eFrost

“…Progressive multifocal leukoencephalopathy (PML) is a severely debilitating and often fatal demyelinating disease of the central nervous system (CNS) in immunosuppressed individuals caused by JC polyomavirus (JCV), a ubiquitous human pathogen. …”
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Cerebrovascular disease, multiple sclerosis, or both? Case report and review of the challenging distinction between two potentially synergistic syndromes by Paola Suarez, Lucas Restrepo

“…Very often, the finding of WMC presents physicians with a very practical problem, which is to determine whether the underlying etiology is an autoimmune demyelinating disease such as multiple sclerosis (MS), or a vasculopathy such as small vessel cerebrovascular disease (SVCVD). …”
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Elevated Fecal Calprotectin Accompanied by Intestinal Neutrophil Infiltration and Goblet Cell Hyperplasia in a Murine Model of Multiple Sclerosis by Mehrnaz Nouri, Björn Weström, Shahram Lavasani

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system caused by myelin-specific autoreactive T cells. …”
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Human iPSC-derived astrocytes generated from donors with globoid cell leukodystrophy display phenotypes associated with disease. by Richard Lieberman, Leslie K Cortes, Grace Gao, Hyejung Park, Bing Wang, Patrick L Jones, R Bridge Hunter, John P Leonard, Robert H Barker

“…Globoid cell leukodystrophy (Krabbe disease) is a fatal neurodegenerative, demyelinating disease caused by dysfunctional activity of galactosylceramidase (GALC), leading to the accumulation of glycosphingolipids including psychosine. …”
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Acute-Onset Retinal Conditions Mimicking Acute Optic Neuritis: Overview and Differential Diagnosis by Emanuela Interlandi, Francesco Pellegrini, Chiara Giuffrè, Daniele Cirone, Daniele Brocca, Andrew G. Lee, Giuseppe Casalino

“…Because of the risk of demyelinating disease, patients affected by unilateral or bilateral optic neuritis should be evaluated and treated accordingly. …”
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CLINICAL EFFECTIVENESS OF HIGH-DOSE IMMUNOSUPPRESSIVE THERAPY WITH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION IN MULTIPLE SCLEROSIS PATIENTS by D. A. Fedorenko, V. Ya. Melnichenko, T. I. Ionova, E. B. Yaroshenko

“…Multiple sclerosis (MS) is a major infl ammatory and demyelinating disease of the central nervous system (CNS), associated with a broad spectrum of physical, psychological, and social impairments. …”
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An Elusive Target: Inhibitors of JC Polyomavirus Infection and Their Development as Therapeutics for the Treatment of Progressive Multifocal Leukoencephalopathy by Jacob Kaiserman, Bethany A. O’Hara, Sheila A. Haley, Walter J. Atwood

“…Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating disease caused by infection with JC Polyomavirus (JCPyV). …”
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MRI features of myelin oligodendrocyte glycoprotein antibody disease: a descriptive study—how it differs from neuromyelitis optica spectrum disorders and multiple sclerosis by J. Tom Mishael, S. Sandeep, Arun George, Babu Philip, Saikanth Deepalam

“…Abstract Background Myelin oligodendrocyte glycoprotein antibody disease (MOGAD) is a novel inflammatory demyelinating disease of the central nervous system. This study aims to characterize the MRI features of MOGAD and contrast our results with the findings previously described in the literature and its close differential diagnoses. …”
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