Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays. by Waters, P, McKeon, A, Leite, M, Rajasekharan, S, Lennon, V, Villalobos, A, Palace, J, Mandrekar, J, Vincent, A, Bar-Or, A, Pittock, S

“… OBJECTIVES: Neuromyelitis optica (NMO) immunoglobulin G (IgG) (aquaporin-4 [AQP4] IgG) is highly specific for NMO and related disorders, and autoantibody detection has become an essential investigation in patients with demyelinating disease. However, although different techniques are now used, no multicenter comparisons have been performed. …”

Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. by Emily Leibovitch, Jillian E Wohler, Sheila M Cummings Macri, Kelsey Motanic, Erin Harberts, María I Gaitán, Pietro Maggi, Mary Ellis, Susan Westmoreland, Afonso Silva, Daniel S Reich, Steven Jacobson

“…HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the CNS. Animal models of HHV-6 infection would help clarify its role in human disease but have been slow to develop because rodents lack CD46, the receptor for cellular entry. …”
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PSEUDOTUMORAL FORM OF MULTIPLE SCLEROSIS WITH SYMPTOMATIC CONVULSIVE SEIZURES (A CLINICAL CASE) by Yu. A. Belova, T. I. Yakushina, I. G. Rudakova

“…The authors provide a clinical case of the pseudotumoral form of MS with convulsive seizures at the onset of demyelinating disease. The problems of diagnosis and therapeutic approaches are discussed.…”
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JCPyV T-Antigen Activation of the Anti-Apoptotic Survivin Promoter—Its Role in the Development of Progressive Multifocal Leukoencephalopathy by Luis Del Valle, Thersa Sweet, Amanda Parker-Struckhoff, Georgina Perez-Liz, Sergio Piña-Oviedo

“…Progressive Multifocal Leukoencephalopathy (PML) is a fatal demyelinating disease of the CNS, resulting from the lytic infection of oligodendrocytes by the human neurotropic polyomavirus JC (JCPyV), typically associated with severe immunocompromised states and, in recent years, with the use of immunotherapies. …”
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Glatiramer acetate 40 mg/ml: A review of the results of GALA and GLACIER clinical studies by N. Yu. Lashch, A. N. Boiko

“…Multiple sclerosis (MS) is a demyelinating disease of the CNS, which affects mainly young able-bodied people; in this connection the problem of MS treatment assumes particular relevance. …”
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Case report: A disconjugate pattern in video head impulse testing hints toward a central cause of acute vertigo by Vincent G. Wettstein, Bertram Feil, Marie-Luise Mono

“…The hypothesis of an inflammatory demyelinating disease of the central nervous system (CNS) was made. …”
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Regulation of CTLA-4 and PD-L1 Expression in Relapsing-Remitting Multiple Sclerosis Patients after Treatment with Fingolimod, IFNβ-1α, Glatiramer Acetate, and Dimethyl Fumarate Dru... by Afshin Derakhshani, Zahra Asadzadeh, Hossein Safarpour, Patrizia Leone, Mahdi Abdoli Shadbad, Ali Heydari, Behzad Baradaran, Vito Racanelli

“…Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS) that is characterized by inflammation which typically results in significant impairment in most patients. …”
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Vitamin D as a Potential Therapy for Multiple Sclerosis: Where Are We? by Samiksha Wasnik, Isha Sharma, David J. Baylink, Xiaolei Tang

“…Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system and is caused by an aberrant immune response to myelin sheath. …”
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Hesperidin plays beneficial roles in disorders associated with the central nervous system: a review by Ayomide Victor Atoki, Patrick Maduabuchi Aja, Tijjani Salihu Shinkafi, Erick Nyakundi Ondari, Chinaza Godswill Awuchi

“…Although the biological activities of hesperidin in neurodegenerative diseases have been evaluated, more investigation into its underlying mechanisms is required to understand its function in a number of central nervous system disorders, including autoimmune demyelinating disease and neurodegenerative diseases. Thus, this study focuses on the potential role of hesperidin in several models of central nervous system neuroinflammation, such as experimental autoimmune encephalomyelitis, and on the potential role of hesperidin in various neurodegenerative diseases, with a focus on its antioxidant, anti-apoptotic, and anti-inflammatory properties. …”
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Association of vitamin D level and CYP27B1 gene polymorphism with multiple sclerosis in Turkish population by Muhsin Elmas, Mustafa Solak, Mehmet Yaman, Saliha Handan Yildiz, Mujgan Erdogan, Tulay Koken

“…Background: Multiple sclerosis (MS) is a demyelinating disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. …”
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Exploring predictors of depressive symptoms in patients with multiple sclerosis: The effect of neuropathic pain, shame, and mindfulness by T. Carvalho, L. Benedito, C. Gomes

“… Introduction Multiple Sclerosis (MS) is a chronic inflammatory, immune-mediated, demyelinating disease of the central nervous system, with a progressive course. …”
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Motor pathway abnormality in multiple sclerosis by Orest Bolbocean, Valentin Bohotin, Cristian Dinu Popescu

“…Background: Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. Motor symptoms represent one of the most frequent and disabling syndrome of MS. …”
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Characterization of JC Polyomavirus Entry by Serotonin Receptors by Melissa Maginnis, Colleen L. Mayberry, Kashif Mehmood, Matthew Parent, Samuel Hess

“…The viral infection and cytolytic destruction of glial cells leads to the development of the fatal demyelinating disease progressive multifocal leukoencephalopathy (PML), for which there are currently no approved treatment options. …”
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Neuromyelitis Optica Spectrum Disorder with Sick Sinus Syndrome: Two Cases and a Literature Review by Huiting Lin, Xinyi Duan, Lina Li, Jinhao Ye, Haibing Xiao

“…Background and objective: Neuromyelitis optica spectrum disorder (NMOSD) is a rare immune-mediated demyelinating disease of the central nervous system (CNS). …”
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Gene expression profiles in Finnish twins with multiple sclerosis by Kaprio Jaakko, Lehtimäki Terho, Airla Nina, Levula Mari, Paalavuo Raija, Kuusisto Hanna, Särkijärvi Silja, Koskenvuo Markku, Elovaara Irina

“…<p>Abstract</p> <p>Background</p> <p>Since genetic alterations influencing susceptibility to multiple sclerosis (MS), the most common autoimmune demyelinating disease of the central nervous system (CNS), are as yet poorly understood, the purpose of this study was to identify genes responsible for MS by studying monozygotic (MZ) twin pairs discordant for MS.…”
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The prevalence of IgG antibodies against milk and milk antigens in patients with multiple sclerosis by Rittika Chunder, Thorsten Heider, Stefanie Kuerten

“…IntroductionMultiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS). …”
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Hormones in experimental autoimmune encephalomyelitis (EAE) animal models by Ghareghani Majid, Ghanbari Amir, Eid Ali, Shaito Abdullah, Mohamed Wael, Mondello Stefania, Zibara Kazem

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) in which activated immune cells attack the CNS and cause inflammation and demyelination. …”
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A Comparison of Sagittal Sections of Short T1inversion Recovery and T2 Weighted Fast Spin Echo Magnetic Resonance Sequences for Detection of Multiple Sclerosis Spinal Cord Lesions by Qusay Abed Fahad, Ameer Shaker Hadi, Shaymaa Fadhil Obaid

“… Background: Multiple sclerosis is a chronic autoimmune inflammatory demyelinating disease of the central nervous system of unknown etiology. …”
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Complex interaction between mutant HNRNPA1 and gE of varicella zoster virus in pathogenesis of multiple sclerosis by Yogita Kattimani, Avinash M. Veerappa

“…Multiple sclerosis (MS) is a demyelinating disease of the central nervous system causing axonal injury, neuronal loss, and atrophy of the central nervous system leading to permanent neurological and clinical disability. …”
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The Predictive Role of Neurobiochemical Markers in Multiple Sclerosis by Esra Fırat Oğuz, Semra Mungan, Fatma Meriç Yılmaz, Müjgan Ercan, Sema Uysal

“…Introduction:Multiple sclerosis (MS) is the most common, chronic, inflammatory, demyelinating disease of the central nervous system. We aimed to evaluate the levels of some neurobiochemical markers in order to evaluate their predictive role in MS.Methods:Fifty-one patients with a diagnosis of MS and 37 healthy subjects were included in the study. …”
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