In vivo tensor-valued diffusion MRI of focal demyelination in white and deep grey matter of rodents by Yi He, Susana Aznar, Hartwig R. Siebner, Tim B. Dyrby

“…Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease leading to damage of white matter (WM) and grey matter (GM). …”
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IL-33 polymorphism rs1929992 and its association with susceptibility to different pattern of multiple sclerosis by Mitra Jamali, Mehdi Rostami Rad, Gholamreza Anani Sarab, Roya Mahdavi

“…Background: Multiple sclerosis is the most common autoimmune demyelinating disease of the central nervous system (CNS). …”
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Sequence analysis of the non-coding control region of John Cunningham virus isolates from patients with multiple sclerosis treated with natalizumab by Marina A. Tyumentseva, Aleksandr I. Tyumentsev, Maria N. Zakharova, Lola S. Askarova, Taras O. Simaniv, Mikhail A. Piradov, Vasily G. Akimkin

“…The John Cunningham virus (JCPyV) causes a fatal demyelinating disease of the central nervous system known as progressive multifocal leukoencephalopathy (PML). …”
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Influence of Genetic Polymorphisms on Clinical Outcomes of Glatiramer Acetate in Multiple Sclerosis Patients by María José Zarzuelo-Romero, Cristina Pérez-Ramírez, Yasmín Cura, María Isabel Carrasco-Campos, Luciana María Marangoni-Iglecias, María Carmen Ramírez-Tortosa, Alberto Jiménez-Morales

“…Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease of autoimmune origin, in which inflammation and demyelination lead to neurodegeneration and progressive disability. …”
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Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod by Yasuyuki Kihara, Yunjiao Zhu, Deepa Jonnalagadda, William Romanow, Carter Palmer, Carter Palmer, Benjamin Siddoway, Richard Rivera, Ranjan Dutta, Bruce D. Trapp, Jerold Chun

“…Multiple sclerosis (MS) is an immune-mediated demyelinating disease that alters central nervous system (CNS) functions. …”
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Epidemiology of multiple sclerosis in the Bryansk Region by Yu. N. Yurchenko, A. N. Yurchenko, I. V. Smagina

“…All the patients are followed up at the Demyelinating Disease Office, Neurology Department, Bryansk Regional Hospital One. …”
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A novel cell-free intrathecal approach with PRP for the treatment of spinal cord multiple sclerosis in cats by Mariam F. Farid, Yara S. Abouelela, Noha A. E. Yasin, Mohamed R. Mousa, Marwa A. Ibrahim, Abdelbary Prince, Hamdy Rizk

“…Abstract Background Multiple sclerosis (MS) is a progressive autoimmune demyelinating disease of the central nervous system. To date, there is no effective therapy for it. …”
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Amide proton transfer MRI differentiates between progressive multifocal leukoencephalopathy and malignant brain tumors: a pilot study by Hirofumi Koike, Minoru Morikawa, Hideki Ishimaru, Reiko Ideguchi, Masataka Uetani, Takeshi Hiu, Takayuki Matsuo, Mitsuharu Miyoshi

“…Abstract Background Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nerve system caused by the John Cunningham virus. …”
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Сauses of Dizziness in Patients with Suspected Stroke by E. V. Shevchenko, G. R. Ramazanov, S. S. Petrikov

“…In 6.9% patients (n=11), the cause of dizziness was hypertensive encephalopathy, 1.9% of patients (n=3) had heart rhythm disturbance, 9.4% of patients (n=15) had psychogenic dizziness, 0.6% of patients (n=1) had demyelinating disease, and 0.6% of patients (n=1) had hemic hypoxia associated with iron deficiency anemia.Conclusion In 70.6% patients with acute dizziness, admitted to hospital with a suspected stroke, peripheral vestibulopathy was revealed. …”
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Blood pressure-related white matter microstructural disintegrity and associated cognitive function impairment in asymptomatic adults by Kevin N Sheth, Guido J Falcone, Seyedmehdi Payabvash, Julián N Acosta, Stefan P Haider, Cyprien Rivier, Audrey C Leasure

“…Background and objectives We aimed to investigate the white matter (WM) microstructural/cytostructural disintegrity patterns related to higher systolic blood pressure (SBP), and whether they mediate SBP effects on cognitive performance in middle-aged adults.Methods Using the UK Biobank study of community-dwelling volunteers aged 40–69 years, we included participants without a history of stroke, dementia, demyelinating disease or traumatic brain injury. We investigated the association of SBP with MRI diffusion metrics: fractional anisotropy (FA), mean diffusivity (MD), intracellular volume fraction (a measure of neurite density), isotropic (free) water volume fraction (ISOVF) and orientation dispersion across WM tracts. …”
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TAAR1 Expression in Human Macrophages and Brain Tissue: A Potential Novel Facet of MS Neuroinflammation by David A. Barnes, Dylan A. Galloway, Marius C. Hoener, Mark D. Berry, Craig S. Moore

“…Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system. Here, we investigate TAAR1 expression in human primary monocytes, peripherally-derived macrophages, and MS brain tissue. …”
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Co-modulation of TNFR1 and TNFR2 in an animal model of multiple sclerosis by Timon Fiedler, Richard Fairless, Kira Pichi, Roman Fischer, Fabian Richter, Roland E. Kontermann, Klaus Pfizenmaier, Ricarda Diem, Sarah K. Williams

“…Conclusion These results further support the potential of regulating the balance of TNFR signalling, through the co-modulation of TNFR1 and TNFR2 activity, as a novel therapeutic approach in treating inflammatory demyelinating disease.…”
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Key role of the gut–microbiota–brain axis via the subdiaphragmatic vagus nerve in demyelination of the cuprizone-treated mouse brain by Xingming Wang, Akifumi Eguchi, Yong Yang, Lijia Chang, Xiayun Wan, Jiajing Shan, Youge Qu, Li Ma, Chisato Mori, Jianjun Yang, Kenji Hashimoto

“…Multiple sclerosis (MS) is the most common demyelinating disease that attacks the central nervous system. …”
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Comparing the Impact of Bariatric Surgery and Diet Therapy on MS Disease-Related Symptoms: A Systematic Review Study (PP-12) by Neda Ramezani, Elahe Ahmadikhonsaraki, Atoosa Khosravi, Alireza Taghdisi Kashani, Azam Eshaghian-Dorcheh, Zahra Karimi, Saba Naghavi, Ghazal Zandieh, Ahmad Pourmohammadi, Amirhossein Davarpanah Jazi, Iman Adibi

“…Multiple sclerosis is a chronic demyelinating disease of the central nervous system that can be exacerbated by obesity-induced systemic inflammation. …”
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Impact of the Voltage-Gated Calcium Channel Antagonist Nimodipine on the Development of Oligodendrocyte Precursor Cells by Michael Enders, Alicia Weier, Rittika Chunder, Young An, Franziska Bremm, Andreas Feigenspan, Christian Buettner, Arif Bülent Ekici, Enrico Mingardo, Benjamin Odermatt, Stefanie Kuerten

“…Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). …”
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Case report: Identification of Hepatitis B Virus in the cerebrospinal fluid of neuromyelitis optica spectrum disorders and successful treatment with ofatumumab and inebilizumab by Linjun Cai, Xu Liu, Hongyu Zhou, Jinmei Li, Dong Zhou, Dong Zhou, Zhen Hong, Zhen Hong, Zhen Hong

“…Neuromyelitis optica spectrum disorder (NMOSD) is a rare demyelinating disease of the central nervous system primarily affecting the optic nerves, spinal cord, and brainstem. …”
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Lethal adulthood myelin breakdown by oligodendrocyte-specific Ddx54 knockout by Hiroaki Oizumi, Yuki Miyamoto, Chika Seiwa, Masahiro Yamamoto, Nozomu Yoshioka, Seiichi Iizuka, Tomohiro Torii, Katsuya Ohbuchi, Kazushige Mizoguchi, Junji Yamauchi, Hiroaki Asou

“…Our results demonstrate that Ddx54 is indispensable for myelin homeostasis, and they provide a demyelinating disease model based on intrinsic disintegration of adult myelin.…”
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<i>Candida tropicalis</i> Systemic Infection Redirects Leukocyte Infiltration to the Kidneys Attenuating Encephalomyelitis by Natália Munhoz-Alves, Luiza Ayumi Nishiyama Mimura, Rosa Marlene Viero, Eduardo Bagagli, Jean Pierre Schatzmann Peron, Alexandrina Sartori, Thais Fernanda de Campos Fraga-Silva

“…Environmental factors, including infections, are strongly associated with the pathogenesis of multiple sclerosis (MS), which is an autoimmune and demyelinating disease of the central nervous system (CNS). …”
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Predictive value of brain atrophy, serum biomarkers and information processing speed for early disease progression in multiple sclerosis by Magdalena Oset, Małgorzata Domowicz, Paula Wildner, Małgorzata Siger, Iwona Karlińska, Mariusz Stasiołek, Mariola Świderek-Matysiak

“…IntroductionMultiple sclerosis (MS) is a chronic autoimmune-mediated demyelinating disease of the central nervous system (CNS). …”
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Acute disseminated encephalomyelitis in children and adolescents - 20-year single-center experience in Serbia by Ostojić Slavica, Kravljanac Ružica, Kovačević Gordana, Vučetić-Tadić Biljana, Gazikalović Slobodan, Sarajlija Adrijan

“…Acute disseminated encephalomyelitis (ADEM) is the most common demyelinating disease of the central nervous system in pediatric patients. …”
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