Long‐term clinical, imaging and cognitive outcomes association with MS immunopathology by Alicja Kalinowska‐Lyszczarz, Jan‐Mendelt Tillema, William Oliver Tobin, Yong Guo, Stephen D. Weigand, Imke Metz, Wolfgang Brück, Hans Lassmann, Monica Giraldo‐Chica, John D. Port, Claudia F. Lucchinetti

“…Abstract Objective In this observational study on a cohort of biopsy‐proven central nervous system demyelinating disease consistent with MS, we examined the relationship between early‐active demyelinating lesion immunopattern (IP) with subsequent clinical course, radiographic progression, and cognitive function. …”
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IFNα and β Mediated JCPyV Suppression through C/EBPβ-LIP Isoform by Dana May, Anna Bellizzi, Workineh Kassa, John M. Cipriaso, Maurizio Caocci, Hassen S. Wollebo

“…Polyomavirus JC (JCPyV) causes the demyelinating disease progressive multifocal leukoencephalopathy (PML). …”
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piRNA and miRNA Can Suppress the Expression of Multiple Sclerosis Candidate Genes by Saltanat Kamenova, Aksholpan Sharapkhanova, Aigul Akimniyazova, Karlygash Kuzhybayeva, Aida Kondybayeva, Aizhan Rakhmetullina, Anna Pyrkova, Anatoliy Ivashchenko

“…Multiple sclerosis (MS) is a common inflammatory demyelinating disease with a high mortality rate. MS is caused by many candidate genes whose specific involvement has yet to be established. …”
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G Protein Coupled Receptors Potentially Involved in Oligodendrogenesis: A Gene Expression Analysis by Neda Karami, Hadi Aligholi, Moosa Rahimi, Hassan Azari, Tahereh kalantari

“… Background: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system characterized by infiltration of inflammatory leukocytes to the CNS followed by oligodendrocyte cell death, myelin sheath destruction, and axonal injury. …”
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Neurological Benefits, Clinical Challenges, and Neuropathologic Promise of Medical Marijuana: A Systematic Review of Cannabinoid Effects in Multiple Sclerosis and Experimental Mode... by Victor Longoria, Hannah Parcel, Bameelia Toma, Annu Minhas, Rana Zeine

“…A systematic review was conducted by a literature search through PubMed, ProQuest, and EBSCO electronic databases for studies reported since 2007 on the use of cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) in MS and in experimental autoimmune encephalomyelitis (EAE), Theiler’s murine encephalomyelitis virus-induced demyelinating disease (TMEV-IDD), and toxin-induced demyelination models. …”
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The Effect of Peripheral Immune Cell Counts on the Risk of Multiple Sclerosis: A Mendelian Randomization Study by Di He, Liyang Liu, Dongchao Shen, Peng Zou, Liying Cui, Liying Cui

“…ObjectivesMultiple sclerosis (MS) is a complex central nervous system (CNS) demyelinating disease, the etiology of which involves the interplay between genetic and environmental factors. …”
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Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation. by Athanasia Mouzaki, Maria Rodi, Nikolaos Dimisianos, Andreas Emmanuil, Dimitra Kalavrizioti, Rosa Lagoudaki, Nikolaos C Grigoriadis, Panagiotis Papathanasopoulos

“…Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central nervous system. Effector T helper cells, mainly Th1 and Th17, cytotoxic T-cells, B-cells, macrophages, microglia, and the cytokines they secrete, are implicated in the initiation and maintenance of a deregulated immune response to myelin antigens and the ensuing immune-mediated demyelination. …”
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Recent Considerations on Gaming Console Based Training for Multiple Sclerosis Rehabilitation by Antonio Celesti, Vincenzo Cimino, Antonino Naro, Simona Portaro, Maria Fazio, Massimo Villari, Rocco Salvatore Calabró

“…Multiple Sclerosis (MS) is a well-known, chronic demyelinating disease of the Central Nervous System (CNS) and one of the most common causes of disability in young adults. …”
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Acute Necrotizing Hemorrhagic Leukoencephalitis by Fatma Ece Bayam, Gülgün Ersöz, Eren Demirtaş, Gülgün Yılmaz Ovalı, Ayşe Sağduyu Kocaman

“…Scientific BACKGROUND: Acute necrotizing hemorrhagic leukoencephalitis (ANHL) is a rare, demyelinating disease of white matter, characterized with fibrinoid necrozis. …”
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TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells by Haritha L. Desu, Placido Illiano, James S. Choi, Maureen C. Ascona, Han Gao, Jae K. Lee, Roberta Brambilla

“…Furthermore, we demonstrated that TNFR2 plays a key role in this process, suggesting that boosting TNFR2 activation or its downstream signals could be an effective strategy to restore OPC reparative capacity in demyelinating disease.…”
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Multiple sclerosis disease-modifying drug use by immigrants: a real-world study by Jonas Graf, Huah Shin Ng, Feng Zhu, Yinshan Zhao, José M. A. Wijnands, Charity Evans, John D. Fisk, Ruth Ann Marrie, Helen Tremlett

“…The index date was the first MS-related healthcare encounter (MS/demyelinating disease-related diagnosis or DMD prescription filled), and ranged from 01/January/1996 to 31/December/2012. …”
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Predictors of severity and outcome of multiple sclerosis relapses by Hassan Saad Hosny, Hatem Samir Shehata, Sandra Ahmed, Ismail Ramadan, Sarah Sherif Abdo, Amr Mohamed Fouad

“…Abstract Background Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS). …”
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Progressive Multifocal Leukoencephalopathy in Systemic Lupus Erythematosus: A Consequence of Patient-Intrinsic or -Extrinsic Factors? by Evgenia Emmanouilidou, Despoina Kosmara, Efrosini Papadaki, Vasileios Mastorodemos, Pantelis Constantoulakis, Argyro Repa, Georgia Christopoulou, Christina Kalpadakis, Nestor Avgoustidis, Konstantinos Thomas, Dimitrios Boumpas, Prodromos Sidiropoulos, George Bertsias

“…Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the central nervous system (CNS) caused by reactivation of the polyomavirus JC (JCV) typically in immunocompromised individuals. …”
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The Sexual Dimorphism in Cerebrospinal Fluid Protein Content Does Not Affect Intrathecal IgG Synthesis in Multiple Sclerosis by Massimiliano Castellazzi, Caterina Ferri, Ginevra Tecilla, André Huss, Paola Crociani, Gaetano Desina, Gianvito Barbella, Alice Piola, Samantha Permunian, Makbule Senel, Maurizio Leone, Hayrettin Tumani, Maura Pugliatti

“…(1) Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) that mainly affects young adults and females more than males. …”
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The effects of neuroinflammation on the subventricular zone neurogenic compartment following Theiler's Murine Encephalomyelitis virus infection and its regulation by Galectin-3 by James, RE

“…Theiler's murine encephalomyelitis virus (TMEV) induces a demyelinating disease in susceptible SJL/J mice, due to persistence of the virus, which models the chronic progressive form of multiple sclerosis. …”

Coexistence of Myelin Oligodendrocyte Glycoprotein Immunoglobulin G and Neuronal or Glial Antibodies in the Central Nervous System: A Systematic Review by Cong Zhao, Pei Liu, Daidi Zhao, Jiaqi Ding, Guangyun Zhang, Hongzeng Li, Jun Guo

“…Background: Myelin oligodendrocyte glycoprotein immunoglobulin G (MOG-IgG) has been considered a diagnostic marker for patients with demyelinating disease, termed “MOG-IgG associated disorder” (MOGAD). …”
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Investigating Serum sHLA-G Cooperation With MRI Activity and Disease-Modifying Treatment Outcome in Relapsing-Remitting Multiple Sclerosis by Roberta Amoriello, Roberta Rizzo, Alice Mariottini, Daria Bortolotti, Valentina Gentili, Elena Bonechi, Alessandra Aldinucci, Alberto Carnasciali, Benedetta Peruzzi, Anna Maria Repice, Luca Massacesi, Luca Massacesi, Enrico Fainardi, Clara Ballerini

“…Relapsing-remitting multiple sclerosis (RRMS) is a demyelinating disease in which pathogenesis T cells have a major role. …”
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Assessment of PD-1 gene variation in patients with multiple sclerosis by Shadmehri AA, Nicknam MH, Shokrgozar MA, Mahmoudi M, Sarial Sh, Ahmadi Shadmehri A, Moradi B, Farhadi E, Amirzargar AA

“…"n Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;} Background: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with presumed autoimmune origin. …”
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CNS demyelinating events in primary Sjögren's syndrome: A single-center case series on the clinical phenotype by Ali M. Afzali, Ali M. Afzali, Philipp Moog, Sudhakar Reddy Kalluri, Benedikt Hofauer, Andreas Knopf, Andreas Knopf, Jan Stefan Kirschke, Bernhard Hemmer, Bernhard Hemmer, Achim Berthele

“…ObjectiveThe study aimed to assess the prevalence, clinical characteristics, and therapeutic outcomes of the central nervous system (CNS) demyelinating disease in a large cohort of primary Sjögren's syndrome (pSS).MethodsThis is an explorative cross-sectional study of patients with pSS seen in the departments of rheumatology, otorhinolaryngology, or neurology of a tertiary university center between January 2015 and September 2021.ResultsIn a cohort of 194 pSS patients, 22 patients had a CNS manifestation. …”
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Ursolic acid derivative UAOS-Na treats experimental autoimmune encephalomyelitis by immunoregulation and protecting myelin by Maolin Wang, Maolin Wang, Chenming Gu, Yifu Yang, Liang Chen, Kaixian Chen, Jun Du, Huali Wu, Yiming Li

“…IntroductionMultiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS). …”
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