Sociodemographic and Illness-Related Indicators to Predict the Status of Neuromyelitis Optica Spectrum Disorder (NMOSD) Five Years after Disease Onset by Dena Sadeghi-Bahmani, Mahdi Barzegar, Omid Mirmosayyeb, Saeed Vaheb, Nasim Nehzat, Vahid Shaygannejad, Serge Brand

“…Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system. Currently, no factors have been identified to predict the long-term course of NMOSD. …”
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Association between vitamin D deficiency and multiple sclerosis- MRI significance: A scoping review by Shorouk Hajeer, Farah Nasr, Sanaa Nabha, Marie-belle Saab, Hayat Harati, Alban Desoutter, Elie Al Ahmar, Elias Estephan

“…Background/Objective: Multiple Sclerosis is a common demyelinating disease of the central nervous system. Several studies suggested a link between vitamin D deficiency and multiple sclerosis disease activity, which can be evaluated by magnetic resonance imaging. …”
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Personality traits of patients with multiple sclerosis and their correlation with anxiety and depression levels: A cross‐sectional case–control study by Amirali Ghahremani, Sahar Mosa Farkhani, Mahsa Baniasadi, Seyed Kaveh Hojjat, Hasan Namdar Ahmadabad, Davoud Salarbashi, Sepideh Elyasi, Najmeh Davoodian

“…Abstract Objective Multiple sclerosis is a chronic demyelinating disease of the central nervous system that can cause severe disability and impair the quality of life (QoL). …”
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Preclinical Therapy with Vitamin D3 in Experimental Encephalomyelitis: Efficacy and Comparison with Paricalcitol by Luiza Ayumi Nishiyama Mimura, Thais Fernanda de Campos Fraga-Silva, Larissa Ragozzo Cardoso de Oliveira, Larissa Lumi Watanabe Ishikawa, Patrícia Aparecida Borim, Carla de Moraes Machado, José de Anchieta de Castro e Horta Júnior, Denise Morais da Fonseca, Alexandrina Sartori

“…Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system (CNS). …”
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Polysialic acid promotes remyelination in cerebellar slice cultures by Siglec-E-dependent modulation of microglia polarization by Lara-Jasmin Schröder, Lara-Jasmin Schröder, Hauke Thiesler, Lina Gretenkort, Thiemo Malte Möllenkamp, Martin Stangel, Martin Stangel, Viktoria Gudi, Herbert Hildebrandt, Herbert Hildebrandt

“…Multiple sclerosis is an inflammatory demyelinating disease of the central nervous system. Spontaneous restoration of myelin after demyelination occurs, but its efficiency declines during disease progression. …”
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Cellular inhibitor of apoptosis 2 (cIAP2) restricts neuroinflammation during experimental autoimmune encephalomyelitis by Debolina D. Biswas, Rebecca K. Martin, LaShardai N. Brown, Karli Mockenhaupt, Angela S. Gupta, Michael J. Surace, Anuj Tharakan, Jessie W. Yester, Reetika Bhardwaj, Daniel H. Conrad, Tomasz Kordula

“…Abstract Background Immune activation, neuroinflammation, and cell death are the hallmarks of multiple sclerosis (MS), which is an autoimmune demyelinating disease of the central nervous system (CNS). …”
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Brain region dependent molecular signatures and myelin repair following chronic demyelination by Grace Samtani, Grace Samtani, Sunja Kim, Danielle Michaud, Andrew E. Hillhouse, Joseph A. Szule, Kranti Konganti, Jianrong Li, Jianrong Li

“…Multiple sclerosis (MS) is the most prevalent demyelinating disease of the central nervous system, characterized by myelin destruction, axonal degeneration, and progressive loss of neurological functions. …”
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Locked‐in syndrome after central pontine myelinolysis, an outstanding outcome of two patients by Maïlys Chabert, Corentin Dauleac, Maude Beaudoin‐Gobert, Mélaine De‐Quelen, Sophie Ciancia, Timothée Jacquesson, Simon Bertrand, Emmanuel Vivier, Donatien De‐Marignan, Julien Jung, Nathalie Andre‐Obadia, Florent Gobert, François Cotton, Jacques Luauté

“…Abstract Objective Central pontine myelinolysis (CPM) is a rare demyelinating disease that affects the pons and which can cause extreme disabilities such as locked‐in syndrome (LIS) in the initial phase. …”
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Teriflunomide Inhibits JCPyV Infection and Spread in Glial Cells and Choroid Plexus Epithelial Cells by Bethany A. O’Hara, Gretchen V. Gee, Sheila A. Haley, Jenna Morris-Love, Charlotte Nyblade, Chris Nieves, Barbara A. Hanson, Xin Dang, Timothy J. Turner, Jeffrey M. Chavin, Alex Lublin, Igor J. Koralnik, Walter J. Atwood

“…Most of these disease-modifying therapies, except teriflunomide, carry the risk of progressive multifocal leukoencephalopathy (PML), a severely debilitating, often fatal virus-induced demyelinating disease. Because teriflunomide has been shown to have antiviral activity against DNA viruses, we investigated whether treatment of cells with teriflunomide inhibits infection and spread of JC polyomavirus (JCPyV), the causative agent of PML. …”
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Assessing ‘no evidence of disease activity’ status in patients with relapsing–remitting multiple sclerosis: a long-term follow-up by Chiara Zilli, Pietro Scribani Rossi, Arianna Di Stadio, Mariangela Fratino, Giada Giuliani, Rosanna Annecca, Gaetano Russo, Vittorio Di Piero, Marta Altieri

“…IntroductionMultiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the CNS with an autoimmune pathogenesis. …”
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CD4+ T cell mitochondrial genotype in Multiple Sclerosis: a cross-sectional and longitudinal analysis by Filipe Cortes-Figueiredo, Susanna Asseyer, Claudia Chien, Hanna G. Zimmermann, Klemens Ruprecht, Tanja Schmitz-Hübsch, Judith Bellmann-Strobl, Friedemann Paul, Vanessa A. Morais

“…Abstract Multiple Sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system (CNS), with a largely unknown etiology, where mitochondrial dysfunction likely contributes to neuroaxonal loss and brain atrophy. …”
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Case report: A case of acute disseminated encephalomyelitis after SARS-CoV-2 infection in pediatric patients by Francesca Cautilli, Mariavittoria Feleppa, Massimiliano Valeriani, Laura Papetti, Gabriele Monte, Fabio Midulla, Alberto Spalice

“…Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disease of the central nervous system. Typically, it presents in childhood and occurs 1 or 2 weeks after infection or vaccination.Case presentationWe present the case of a 12-year-old boy who developed ADEM, 10 days after an asymptomatic SARS-CoV-2 infection. …”
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Siponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways by Mikel Gurrea-Rubio, Qin Wang, Elizabeth A. Mills, Qi Wu, David Pitt, Pei-Suen Tsou, David A. Fox, Yang Mao-Draayer

“…Multiple sclerosis (MS) is the most common autoimmune demyelinating disease of the central nervous system (CNS), consisting of heterogeneous clinical courses varying from relapsing-remitting MS (RRMS), in which disability is linked to bouts of inflammation, to progressive disease such as primary progressive MS (PPMS) and secondary progressive MS (SPMS), in which neurological disability is thought to be linked to neurodegeneration. …”
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ACT001 Relieves NMOSD Symptoms by Reducing Astrocyte Damage with an Autoimmune Antibody by Hongen Li, Mo Yang, Honglu Song, Mingming Sun, Huanfen Zhou, Junxia Fu, Di Zhou, Wenhao Bai, Biyue Chen, Mengying Lai, Hao Kang, Shihui Wei

“…Neuromyelitis optica spectrum disorder (NMOSD) is a central nervous system inflammatory demyelinating disease, the pathogenesis of which involves autoantibodies targeting the extracellular epitopes of aquaporin-4 on astrocytes. …”
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Two case reports and a systematic review of the literature on adult cerebral cortical encephalitis with anti-myelin oligodendrocyte glycoprotein antibody by Meihui Xu, Chi Ma, Ming Dong, Chunjie Guo, Simin Yang, Yue Liu, Xu Wang

“…Background and purposeMyelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has gained recognition in recent years as an immune-mediated inflammatory demyelinating disease of the central nervous system. The clinical features and prognosis of MOGAD adult cerebral cortical encephalitis (adult CCE) have not been fully elucidated. …”
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Obesity induced gut dysbiosis contributes to disease severity in an animal model of multiple sclerosis by Shailesh K. Shahi, Sudeep Ghimire, Peter Lehman, Ashutosh K. Mangalam, Ashutosh K. Mangalam, Ashutosh K. Mangalam

“…BackgroundMultiple sclerosis (MS) is an inflammatory and demyelinating disease of the CNS. The etiology of MS is complex, and results from the interaction of multiple environmental and genetic factors. …”
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Alpha-asaronol promoted oligodendrocyte precursor cell differentiation and improved myelination as an activator PPARγ by Zhaowei Feng, Zixuan Gao, Renyu Kong, Tao Zhuang, Jing Liu, Ting Liu, Xiaohui Zheng, Yajun Bai, Ruiqin Yao

“…Preterm white matter injury (PWMI), characterized by oligodendrocyte precursor cell (OPC) differentiation disorder and dysmyelination, is a prevalent demyelinating disease of the central nervous system in premature infants, necessitating the development of mitigating strategies. …”
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Characterisation of astrocyte diversity in the multiple sclerosis motor cortex by Yee, S

“…<p>Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system where neurodegeneration often leads to irreversible disability. …”

Clinical and Radiological Characterization of Progressive Multifocal Leukoencephalopathy in HIV-Infected Patients: A Retrospective Analysis and Review of the Literature by Luís Augusto, Nélia Neves, Carina Reis, Cândida Abreu, António Sarmento

“… Introduction: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by John Cunningham virus, mostly associated with immunodeficiency conditions, such as the human immunodeficiency virus infection. …”
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Value contribution of blood-based neurofilament light chain as a biomarker in multiple sclerosis using multi-criteria decision analysis by Enric Monreal, Pilar Díaz Ruiz, Isabel López San Román, Alfredo Rodríguez-Antigüedad, Miguel Ángel Moya-Molina, Ana Álvarez, Elena García-Arcelay, Jorge Maurino, John Shepherd, Álvaro Pérez Cabrera, Luisa María Villar

“…IntroductionMultiple sclerosis (MS) is a chronic autoimmune demyelinating disease that represents a leading cause of non-traumatic disability among young and middle-aged adults. …”
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